| Full name: zinc finger and BTB domain containing 17 | Alias Symbol: MIZ1|pHZ-67 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 7709 | HGNC ID: HGNC:12936 | Ensembl Gene: ENSG00000116809 | OMIM ID: 604084 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
ZBTB17 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04110 | Cell cycle |
Expression of ZBTB17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB17 | 7709 | 203602_s_at | 0.4091 | 0.1907 | |
| GSE20347 | ZBTB17 | 7709 | 203602_s_at | 0.0901 | 0.2710 | |
| GSE23400 | ZBTB17 | 7709 | 203602_s_at | 0.1158 | 0.0333 | |
| GSE26886 | ZBTB17 | 7709 | 203602_s_at | 0.2217 | 0.2466 | |
| GSE29001 | ZBTB17 | 7709 | 203602_s_at | 0.0889 | 0.6703 | |
| GSE38129 | ZBTB17 | 7709 | 203602_s_at | 0.1155 | 0.1454 | |
| GSE45670 | ZBTB17 | 7709 | 203602_s_at | 0.3596 | 0.0075 | |
| GSE53622 | ZBTB17 | 7709 | 72296 | -1.7284 | 0.0000 | |
| GSE53624 | ZBTB17 | 7709 | 72296 | -1.1778 | 0.0000 | |
| GSE63941 | ZBTB17 | 7709 | 203602_s_at | -0.3375 | 0.1642 | |
| GSE77861 | ZBTB17 | 7709 | 203601_s_at | -0.1278 | 0.3906 | |
| GSE97050 | ZBTB17 | 7709 | A_23_P654 | -0.1485 | 0.5940 | |
| SRP007169 | ZBTB17 | 7709 | RNAseq | -0.5871 | 0.2047 | |
| SRP008496 | ZBTB17 | 7709 | RNAseq | -0.4155 | 0.2012 | |
| SRP064894 | ZBTB17 | 7709 | RNAseq | 0.4660 | 0.0093 | |
| SRP133303 | ZBTB17 | 7709 | RNAseq | 0.1491 | 0.3972 | |
| SRP159526 | ZBTB17 | 7709 | RNAseq | 0.2158 | 0.6056 | |
| SRP193095 | ZBTB17 | 7709 | RNAseq | 0.3578 | 0.0018 | |
| SRP219564 | ZBTB17 | 7709 | RNAseq | -0.1073 | 0.5801 | |
| TCGA | ZBTB17 | 7709 | RNAseq | -0.0261 | 0.6256 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZBTB17 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB17 | 7709 | 1 | 5 | 24 | |
| GSE20123 | ZBTB17 | 7709 | 1 | 4 | 25 | |
| GSE43470 | ZBTB17 | 7709 | 1 | 8 | 34 | |
| GSE46452 | ZBTB17 | 7709 | 7 | 1 | 51 | |
| GSE47630 | ZBTB17 | 7709 | 8 | 3 | 29 | |
| GSE54993 | ZBTB17 | 7709 | 3 | 1 | 66 | |
| GSE54994 | ZBTB17 | 7709 | 10 | 4 | 39 | |
| GSE60625 | ZBTB17 | 7709 | 0 | 0 | 11 | |
| GSE74703 | ZBTB17 | 7709 | 1 | 5 | 30 | |
| GSE74704 | ZBTB17 | 7709 | 1 | 0 | 19 | |
| TCGA | ZBTB17 | 7709 | 12 | 23 | 61 |
Total number of gains: 45; Total number of losses: 54; Total Number of normals: 389.
Somatic mutations of ZBTB17:
Generating mutation plots.
Highly correlated genes for ZBTB17:
Showing top 20/179 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB17 | FAM163B | 0.82884 | 3 | 0 | 3 |
| ZBTB17 | MFSD2B | 0.805923 | 3 | 0 | 3 |
| ZBTB17 | IQCF1 | 0.80488 | 4 | 0 | 4 |
| ZBTB17 | KRTAP20-1 | 0.798522 | 3 | 0 | 3 |
| ZBTB17 | OTOP3 | 0.778444 | 3 | 0 | 3 |
| ZBTB17 | OR2Z1 | 0.778084 | 3 | 0 | 3 |
| ZBTB17 | MUC22 | 0.773905 | 3 | 0 | 3 |
| ZBTB17 | FAM24B | 0.769224 | 3 | 0 | 3 |
| ZBTB17 | KPRP | 0.748354 | 3 | 0 | 3 |
| ZBTB17 | TMPRSS11A | 0.745706 | 3 | 0 | 3 |
| ZBTB17 | WDR83 | 0.743989 | 3 | 0 | 3 |
| ZBTB17 | APOA1 | 0.743284 | 4 | 0 | 3 |
| ZBTB17 | RNF222 | 0.742598 | 3 | 0 | 3 |
| ZBTB17 | ANKRD24 | 0.741554 | 4 | 0 | 3 |
| ZBTB17 | BTBD19 | 0.739479 | 4 | 0 | 4 |
| ZBTB17 | OR10G8 | 0.738412 | 3 | 0 | 3 |
| ZBTB17 | ARHGAP40 | 0.738115 | 3 | 0 | 3 |
| ZBTB17 | GPX6 | 0.733176 | 3 | 0 | 3 |
| ZBTB17 | YJEFN3 | 0.721463 | 3 | 0 | 3 |
| ZBTB17 | NCCRP1 | 0.714711 | 4 | 0 | 3 |
For details and further investigation, click here
