| Full name: keratinocyte proline rich protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 448834 | HGNC ID: HGNC:31823 | Ensembl Gene: ENSG00000203786 | OMIM ID: 613260 |
| Drug and gene relationship at DGIdb | |||
Expression of KPRP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | KPRP | 448834 | 18900 | -2.2058 | 0.0000 | |
| GSE53624 | KPRP | 448834 | 18900 | -2.8513 | 0.0000 | |
| GSE97050 | KPRP | 448834 | A_33_P3312519 | -0.8300 | 0.2119 | |
| SRP007169 | KPRP | 448834 | RNAseq | -7.1280 | 0.0000 | |
| SRP064894 | KPRP | 448834 | RNAseq | -4.6082 | 0.0000 | |
| SRP133303 | KPRP | 448834 | RNAseq | -5.2863 | 0.0000 | |
| SRP159526 | KPRP | 448834 | RNAseq | -3.0282 | 0.0620 | |
| TCGA | KPRP | 448834 | RNAseq | 0.2210 | 0.7291 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by KPRP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KPRP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KPRP | 448834 | 15 | 0 | 15 | |
| GSE20123 | KPRP | 448834 | 15 | 0 | 15 | |
| GSE43470 | KPRP | 448834 | 6 | 2 | 35 | |
| GSE46452 | KPRP | 448834 | 3 | 1 | 55 | |
| GSE47630 | KPRP | 448834 | 15 | 0 | 25 | |
| GSE54993 | KPRP | 448834 | 0 | 4 | 66 | |
| GSE54994 | KPRP | 448834 | 15 | 0 | 38 | |
| GSE60625 | KPRP | 448834 | 0 | 0 | 11 | |
| GSE74703 | KPRP | 448834 | 6 | 1 | 29 | |
| GSE74704 | KPRP | 448834 | 7 | 0 | 13 | |
| TCGA | KPRP | 448834 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of KPRP:
Generating mutation plots.
Highly correlated genes for KPRP:
Showing top 20/379 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KPRP | VSIG10L | 0.84999 | 3 | 0 | 3 |
| KPRP | RAET1E | 0.849165 | 3 | 0 | 3 |
| KPRP | ZNF365 | 0.847028 | 3 | 0 | 3 |
| KPRP | APOA1 | 0.84312 | 3 | 0 | 3 |
| KPRP | ACER1 | 0.83393 | 3 | 0 | 3 |
| KPRP | IL36A | 0.833512 | 3 | 0 | 3 |
| KPRP | ARID5A | 0.830046 | 3 | 0 | 3 |
| KPRP | ECM1 | 0.827122 | 3 | 0 | 3 |
| KPRP | EPS8L2 | 0.826676 | 3 | 0 | 3 |
| KPRP | RNF222 | 0.825361 | 3 | 0 | 3 |
| KPRP | C3orf20 | 0.823829 | 3 | 0 | 3 |
| KPRP | DEGS2 | 0.82351 | 3 | 0 | 3 |
| KPRP | TGM3 | 0.821824 | 3 | 0 | 3 |
| KPRP | UPK1A | 0.821656 | 3 | 0 | 3 |
| KPRP | MXD1 | 0.821508 | 3 | 0 | 3 |
| KPRP | IQCF1 | 0.818498 | 3 | 0 | 3 |
| KPRP | NCR1 | 0.81628 | 3 | 0 | 3 |
| KPRP | PMM1 | 0.816101 | 3 | 0 | 3 |
| KPRP | HES5 | 0.811459 | 3 | 0 | 3 |
| KPRP | CRABP2 | 0.810324 | 3 | 0 | 3 |
For details and further investigation, click here
