| Full name: ring finger protein 222 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 643904 | HGNC ID: HGNC:34517 | Ensembl Gene: ENSG00000189051 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNF222:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | RNF222 | 643904 | 24139 | -1.2963 | 0.0000 | |
| GSE53624 | RNF222 | 643904 | 24139 | -1.8383 | 0.0000 | |
| GSE97050 | RNF222 | 643904 | A_33_P3318444 | -0.3143 | 0.4794 | |
| SRP007169 | RNF222 | 643904 | RNAseq | -5.4819 | 0.0000 | |
| SRP008496 | RNF222 | 643904 | RNAseq | -5.2905 | 0.0000 | |
| SRP064894 | RNF222 | 643904 | RNAseq | -3.6932 | 0.0000 | |
| SRP133303 | RNF222 | 643904 | RNAseq | -2.9606 | 0.0000 | |
| SRP159526 | RNF222 | 643904 | RNAseq | -4.7608 | 0.0000 | |
| SRP193095 | RNF222 | 643904 | RNAseq | -3.0011 | 0.0000 | |
| SRP219564 | RNF222 | 643904 | RNAseq | -5.0940 | 0.0000 | |
| TCGA | RNF222 | 643904 | RNAseq | 0.3536 | 0.4679 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by RNF222 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF222:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF222 | 643904 | 4 | 2 | 24 | |
| GSE20123 | RNF222 | 643904 | 4 | 3 | 23 | |
| GSE43470 | RNF222 | 643904 | 1 | 6 | 36 | |
| GSE46452 | RNF222 | 643904 | 34 | 1 | 24 | |
| GSE47630 | RNF222 | 643904 | 7 | 1 | 32 | |
| GSE54993 | RNF222 | 643904 | 4 | 3 | 63 | |
| GSE54994 | RNF222 | 643904 | 5 | 8 | 40 | |
| GSE60625 | RNF222 | 643904 | 4 | 0 | 7 | |
| GSE74703 | RNF222 | 643904 | 1 | 3 | 32 | |
| GSE74704 | RNF222 | 643904 | 2 | 1 | 17 | |
| TCGA | RNF222 | 643904 | 18 | 20 | 58 |
Total number of gains: 84; Total number of losses: 48; Total Number of normals: 356.
Somatic mutations of RNF222:
Generating mutation plots.
Highly correlated genes for RNF222:
Showing top 20/355 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF222 | IVL | 0.892135 | 3 | 0 | 3 |
| RNF222 | GPR62 | 0.879642 | 3 | 0 | 3 |
| RNF222 | NOTO | 0.865959 | 3 | 0 | 3 |
| RNF222 | HAMP | 0.864461 | 3 | 0 | 3 |
| RNF222 | NHLRC4 | 0.86079 | 3 | 0 | 3 |
| RNF222 | ATP2B3 | 0.855847 | 3 | 0 | 3 |
| RNF222 | KCNA7 | 0.852095 | 3 | 0 | 3 |
| RNF222 | DCD | 0.84928 | 3 | 0 | 3 |
| RNF222 | CYP11A1 | 0.84217 | 3 | 0 | 3 |
| RNF222 | FAM163B | 0.833387 | 3 | 0 | 3 |
| RNF222 | APOA1 | 0.831947 | 3 | 0 | 3 |
| RNF222 | PRSS27 | 0.830138 | 3 | 0 | 3 |
| RNF222 | HMGB4 | 0.828457 | 3 | 0 | 3 |
| RNF222 | DEGS2 | 0.826778 | 3 | 0 | 3 |
| RNF222 | ACER1 | 0.82584 | 3 | 0 | 3 |
| RNF222 | KPRP | 0.825361 | 3 | 0 | 3 |
| RNF222 | NCCRP1 | 0.8189 | 3 | 0 | 3 |
| RNF222 | KLK2 | 0.818406 | 3 | 0 | 3 |
| RNF222 | ALS2CL | 0.810955 | 3 | 0 | 3 |
| RNF222 | GPHB5 | 0.809551 | 3 | 0 | 3 |
For details and further investigation, click here
