| Full name: WD repeat domain 83 | Alias Symbol: MORG1 | ||
| Type: protein-coding gene | Cytoband: 19p13.13 | ||
| Entrez ID: 84292 | HGNC ID: HGNC:32672 | Ensembl Gene: ENSG00000123154 | OMIM ID: 616850 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of WDR83:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR83 | 84292 | 224434_s_at | 0.3066 | 0.3318 | |
| GSE26886 | WDR83 | 84292 | 224434_s_at | 0.0648 | 0.7280 | |
| GSE45670 | WDR83 | 84292 | 224434_s_at | 0.1044 | 0.2580 | |
| GSE53622 | WDR83 | 84292 | 86749 | 0.0735 | 0.1926 | |
| GSE53624 | WDR83 | 84292 | 86749 | 0.3242 | 0.0000 | |
| GSE63941 | WDR83 | 84292 | 224434_s_at | 0.5876 | 0.1101 | |
| GSE77861 | WDR83 | 84292 | 224434_s_at | -0.0298 | 0.8842 | |
| GSE97050 | WDR83 | 84292 | A_23_P39024 | 0.1023 | 0.6882 | |
| SRP007169 | WDR83 | 84292 | RNAseq | 0.8938 | 0.2185 | |
| SRP064894 | WDR83 | 84292 | RNAseq | 0.8352 | 0.0012 | |
| SRP133303 | WDR83 | 84292 | RNAseq | -0.1740 | 0.2810 | |
| SRP159526 | WDR83 | 84292 | RNAseq | 0.2933 | 0.2982 | |
| SRP193095 | WDR83 | 84292 | RNAseq | 0.1741 | 0.1388 | |
| SRP219564 | WDR83 | 84292 | RNAseq | 0.4461 | 0.3213 | |
| TCGA | WDR83 | 84292 | RNAseq | 0.0793 | 0.3329 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR83 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR83:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR83 | 84292 | 4 | 2 | 24 | |
| GSE20123 | WDR83 | 84292 | 3 | 1 | 26 | |
| GSE43470 | WDR83 | 84292 | 2 | 6 | 35 | |
| GSE46452 | WDR83 | 84292 | 47 | 1 | 11 | |
| GSE47630 | WDR83 | 84292 | 4 | 7 | 29 | |
| GSE54993 | WDR83 | 84292 | 16 | 3 | 51 | |
| GSE54994 | WDR83 | 84292 | 6 | 13 | 34 | |
| GSE60625 | WDR83 | 84292 | 9 | 0 | 2 | |
| GSE74703 | WDR83 | 84292 | 2 | 4 | 30 | |
| GSE74704 | WDR83 | 84292 | 0 | 1 | 19 | |
| TCGA | WDR83 | 84292 | 16 | 13 | 67 |
Total number of gains: 109; Total number of losses: 51; Total Number of normals: 328.
Somatic mutations of WDR83:
Generating mutation plots.
Highly correlated genes for WDR83:
Showing top 20/158 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR83 | ITGA2B | 0.890847 | 3 | 0 | 3 |
| WDR83 | MIIP | 0.868613 | 3 | 0 | 3 |
| WDR83 | TRIM31 | 0.809415 | 3 | 0 | 3 |
| WDR83 | ABHD11 | 0.789317 | 3 | 0 | 3 |
| WDR83 | COPS7B | 0.787498 | 3 | 0 | 3 |
| WDR83 | ING5 | 0.784442 | 3 | 0 | 3 |
| WDR83 | RBM28 | 0.780624 | 3 | 0 | 3 |
| WDR83 | USP27X | 0.744336 | 3 | 0 | 3 |
| WDR83 | ZBTB17 | 0.743989 | 3 | 0 | 3 |
| WDR83 | CEP104 | 0.736515 | 3 | 0 | 3 |
| WDR83 | OTOP2 | 0.732913 | 3 | 0 | 3 |
| WDR83 | CD247 | 0.728763 | 3 | 0 | 3 |
| WDR83 | SPC24 | 0.72833 | 3 | 0 | 3 |
| WDR83 | NUBP2 | 0.724197 | 3 | 0 | 3 |
| WDR83 | FAM24B | 0.711612 | 4 | 0 | 3 |
| WDR83 | TMEM52 | 0.708664 | 3 | 0 | 3 |
| WDR83 | ZNF221 | 0.708402 | 3 | 0 | 3 |
| WDR83 | TULP1 | 0.703738 | 3 | 0 | 3 |
| WDR83 | LRFN4 | 0.701545 | 4 | 0 | 3 |
| WDR83 | SIL1 | 0.701168 | 3 | 0 | 3 |
For details and further investigation, click here
