| Full name: zinc finger DHHC-type containing 3 | Alias Symbol: ZNF373|GODZ|DHHC3 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 51304 | HGNC ID: HGNC:18470 | Ensembl Gene: ENSG00000163812 | OMIM ID: 617150 |
| Drug and gene relationship at DGIdb | |||
Expression of ZDHHC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZDHHC3 | 51304 | 218078_s_at | -0.8386 | 0.0559 | |
| GSE20347 | ZDHHC3 | 51304 | 218078_s_at | -1.0929 | 0.0000 | |
| GSE23400 | ZDHHC3 | 51304 | 218078_s_at | -0.5690 | 0.0000 | |
| GSE26886 | ZDHHC3 | 51304 | 218078_s_at | -1.3633 | 0.0000 | |
| GSE29001 | ZDHHC3 | 51304 | 218078_s_at | -0.5468 | 0.0057 | |
| GSE38129 | ZDHHC3 | 51304 | 218078_s_at | -0.8334 | 0.0000 | |
| GSE45670 | ZDHHC3 | 51304 | 218078_s_at | -0.3340 | 0.0438 | |
| GSE53622 | ZDHHC3 | 51304 | 75524 | -0.7287 | 0.0000 | |
| GSE53624 | ZDHHC3 | 51304 | 75524 | -0.7945 | 0.0000 | |
| GSE63941 | ZDHHC3 | 51304 | 218078_s_at | -0.4356 | 0.3722 | |
| GSE77861 | ZDHHC3 | 51304 | 218078_s_at | -0.3347 | 0.1214 | |
| GSE97050 | ZDHHC3 | 51304 | A_24_P351420 | -0.7477 | 0.0620 | |
| SRP007169 | ZDHHC3 | 51304 | RNAseq | -0.7940 | 0.0090 | |
| SRP008496 | ZDHHC3 | 51304 | RNAseq | -0.5183 | 0.0089 | |
| SRP064894 | ZDHHC3 | 51304 | RNAseq | -0.6501 | 0.0000 | |
| SRP133303 | ZDHHC3 | 51304 | RNAseq | -0.5265 | 0.0129 | |
| SRP159526 | ZDHHC3 | 51304 | RNAseq | -0.5005 | 0.0585 | |
| SRP193095 | ZDHHC3 | 51304 | RNAseq | -0.9121 | 0.0000 | |
| SRP219564 | ZDHHC3 | 51304 | RNAseq | -1.1205 | 0.0005 | |
| TCGA | ZDHHC3 | 51304 | RNAseq | -0.1583 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ZDHHC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZDHHC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZDHHC3 | 51304 | 0 | 17 | 13 | |
| GSE20123 | ZDHHC3 | 51304 | 0 | 17 | 13 | |
| GSE43470 | ZDHHC3 | 51304 | 0 | 21 | 22 | |
| GSE46452 | ZDHHC3 | 51304 | 2 | 17 | 40 | |
| GSE47630 | ZDHHC3 | 51304 | 1 | 24 | 15 | |
| GSE54993 | ZDHHC3 | 51304 | 7 | 2 | 61 | |
| GSE54994 | ZDHHC3 | 51304 | 0 | 35 | 18 | |
| GSE60625 | ZDHHC3 | 51304 | 5 | 0 | 6 | |
| GSE74703 | ZDHHC3 | 51304 | 0 | 16 | 20 | |
| GSE74704 | ZDHHC3 | 51304 | 0 | 12 | 8 | |
| TCGA | ZDHHC3 | 51304 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 235; Total Number of normals: 237.
Somatic mutations of ZDHHC3:
Generating mutation plots.
Highly correlated genes for ZDHHC3:
Showing top 20/1604 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZDHHC3 | ANKRD37 | 0.786002 | 3 | 0 | 3 |
| ZDHHC3 | RBPJL | 0.784893 | 3 | 0 | 3 |
| ZDHHC3 | GBP6 | 0.754286 | 4 | 0 | 4 |
| ZDHHC3 | SMO | 0.747938 | 3 | 0 | 3 |
| ZDHHC3 | HIGD1A | 0.743579 | 10 | 0 | 10 |
| ZDHHC3 | ZNF585A | 0.740798 | 3 | 0 | 3 |
| ZDHHC3 | AK3 | 0.737394 | 6 | 0 | 5 |
| ZDHHC3 | ZFC3H1 | 0.734772 | 3 | 0 | 3 |
| ZDHHC3 | CCDC7 | 0.734219 | 3 | 0 | 3 |
| ZDHHC3 | SYTL4 | 0.733997 | 3 | 0 | 3 |
| ZDHHC3 | CLEC3B | 0.731011 | 3 | 0 | 3 |
| ZDHHC3 | MPP7 | 0.72685 | 7 | 0 | 6 |
| ZDHHC3 | SAMD5 | 0.724959 | 7 | 0 | 7 |
| ZDHHC3 | CCNYL1 | 0.721919 | 5 | 0 | 4 |
| ZDHHC3 | DYNLT3 | 0.719948 | 11 | 0 | 10 |
| ZDHHC3 | ARGLU1 | 0.719203 | 3 | 0 | 3 |
| ZDHHC3 | ABLIM1 | 0.717784 | 11 | 0 | 11 |
| ZDHHC3 | CA13 | 0.71753 | 3 | 0 | 3 |
| ZDHHC3 | MGST2 | 0.716736 | 11 | 0 | 11 |
| ZDHHC3 | SEC23IP | 0.716563 | 3 | 0 | 3 |
For details and further investigation, click here
