| Full name: carbonic anhydrase 13 | Alias Symbol: CAXIII|FLJ37995|MGC59868 | ||
| Type: protein-coding gene | Cytoband: 8q21.2 | ||
| Entrez ID: 377677 | HGNC ID: HGNC:14914 | Ensembl Gene: ENSG00000185015 | OMIM ID: 611436 |
| Drug and gene relationship at DGIdb | |||
Expression of CA13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CA13 | 377677 | 9812 | -2.1194 | 0.0000 | |
| GSE53624 | CA13 | 377677 | 9812 | -2.5741 | 0.0000 | |
| GSE97050 | CA13 | 377677 | A_23_P381714 | -0.8074 | 0.1592 | |
| SRP007169 | CA13 | 377677 | RNAseq | -2.8400 | 0.0000 | |
| SRP008496 | CA13 | 377677 | RNAseq | -2.7442 | 0.0000 | |
| SRP064894 | CA13 | 377677 | RNAseq | -1.5001 | 0.0000 | |
| SRP133303 | CA13 | 377677 | RNAseq | -1.7322 | 0.0000 | |
| SRP159526 | CA13 | 377677 | RNAseq | -1.3989 | 0.0002 | |
| SRP193095 | CA13 | 377677 | RNAseq | -1.4900 | 0.0000 | |
| SRP219564 | CA13 | 377677 | RNAseq | -1.7611 | 0.0016 | |
| TCGA | CA13 | 377677 | RNAseq | -0.8239 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by CA13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CA13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CA13 | 377677 | 13 | 2 | 15 | |
| GSE20123 | CA13 | 377677 | 15 | 2 | 13 | |
| GSE43470 | CA13 | 377677 | 18 | 1 | 24 | |
| GSE46452 | CA13 | 377677 | 21 | 0 | 38 | |
| GSE47630 | CA13 | 377677 | 23 | 0 | 17 | |
| GSE54993 | CA13 | 377677 | 0 | 19 | 51 | |
| GSE54994 | CA13 | 377677 | 29 | 1 | 23 | |
| GSE60625 | CA13 | 377677 | 0 | 4 | 7 | |
| GSE74703 | CA13 | 377677 | 15 | 1 | 20 | |
| GSE74704 | CA13 | 377677 | 10 | 0 | 10 | |
| TCGA | CA13 | 377677 | 54 | 2 | 40 |
Total number of gains: 198; Total number of losses: 32; Total Number of normals: 258.
Somatic mutations of CA13:
Generating mutation plots.
Highly correlated genes for CA13:
Showing top 20/709 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CA13 | RNF141 | 0.858821 | 3 | 0 | 3 |
| CA13 | SLC16A6 | 0.852775 | 3 | 0 | 3 |
| CA13 | TAB3 | 0.849831 | 3 | 0 | 3 |
| CA13 | HPGD | 0.84791 | 3 | 0 | 3 |
| CA13 | SLC10A5 | 0.847256 | 3 | 0 | 3 |
| CA13 | C18orf25 | 0.842983 | 3 | 0 | 3 |
| CA13 | SASH1 | 0.842647 | 3 | 0 | 3 |
| CA13 | CCNG2 | 0.840792 | 3 | 0 | 3 |
| CA13 | SIM2 | 0.83918 | 3 | 0 | 3 |
| CA13 | RAB11A | 0.839165 | 3 | 0 | 3 |
| CA13 | SH3BGRL2 | 0.837449 | 3 | 0 | 3 |
| CA13 | ANXA9 | 0.835779 | 3 | 0 | 3 |
| CA13 | CDKN2AIP | 0.835703 | 3 | 0 | 3 |
| CA13 | RMND5B | 0.835309 | 3 | 0 | 3 |
| CA13 | CAST | 0.831333 | 3 | 0 | 3 |
| CA13 | THSD4 | 0.830497 | 3 | 0 | 3 |
| CA13 | WDR26 | 0.82825 | 3 | 0 | 3 |
| CA13 | USP6NL | 0.826547 | 3 | 0 | 3 |
| CA13 | VPS4B | 0.824091 | 3 | 0 | 3 |
| CA13 | MGLL | 0.8236 | 3 | 0 | 3 |
For details and further investigation, click here
