| Full name: C-type lectin domain family 3 member B | Alias Symbol: TN | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 7123 | HGNC ID: HGNC:11891 | Ensembl Gene: ENSG00000163815 | OMIM ID: 187520 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC3B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | CLEC3B | 7123 | 45429 | -2.9563 | 0.0000 | |
| GSE53624 | CLEC3B | 7123 | 45429 | -2.4512 | 0.0000 | |
| GSE97050 | CLEC3B | 7123 | A_23_P69497 | -1.7763 | 0.0620 | |
| SRP007169 | CLEC3B | 7123 | RNAseq | -2.0168 | 0.0039 | |
| SRP064894 | CLEC3B | 7123 | RNAseq | -2.1632 | 0.0016 | |
| SRP133303 | CLEC3B | 7123 | RNAseq | -2.8438 | 0.0000 | |
| SRP159526 | CLEC3B | 7123 | RNAseq | -1.6142 | 0.0079 | |
| SRP193095 | CLEC3B | 7123 | RNAseq | -0.6938 | 0.0392 | |
| SRP219564 | CLEC3B | 7123 | RNAseq | -0.3758 | 0.7120 | |
| TCGA | CLEC3B | 7123 | RNAseq | -1.5912 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by CLEC3B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC3B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC3B | 7123 | 0 | 17 | 13 | |
| GSE20123 | CLEC3B | 7123 | 0 | 17 | 13 | |
| GSE43470 | CLEC3B | 7123 | 0 | 21 | 22 | |
| GSE46452 | CLEC3B | 7123 | 2 | 17 | 40 | |
| GSE47630 | CLEC3B | 7123 | 1 | 24 | 15 | |
| GSE54993 | CLEC3B | 7123 | 7 | 2 | 61 | |
| GSE54994 | CLEC3B | 7123 | 0 | 35 | 18 | |
| GSE60625 | CLEC3B | 7123 | 5 | 0 | 6 | |
| GSE74703 | CLEC3B | 7123 | 0 | 16 | 20 | |
| GSE74704 | CLEC3B | 7123 | 0 | 12 | 8 | |
| TCGA | CLEC3B | 7123 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 235; Total Number of normals: 237.
Somatic mutations of CLEC3B:
Generating mutation plots.
Highly correlated genes for CLEC3B:
Showing top 20/752 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC3B | CFD | 0.930322 | 3 | 0 | 3 |
| CLEC3B | CYP21A2 | 0.925927 | 3 | 0 | 3 |
| CLEC3B | RCAN2 | 0.910701 | 3 | 0 | 3 |
| CLEC3B | ASPA | 0.9077 | 3 | 0 | 3 |
| CLEC3B | ANGPTL1 | 0.899345 | 3 | 0 | 3 |
| CLEC3B | PLAC9 | 0.8969 | 3 | 0 | 3 |
| CLEC3B | LDB3 | 0.891693 | 3 | 0 | 3 |
| CLEC3B | ABCA8 | 0.883199 | 3 | 0 | 3 |
| CLEC3B | OGN | 0.883135 | 3 | 0 | 3 |
| CLEC3B | TGFBR3 | 0.881561 | 3 | 0 | 3 |
| CLEC3B | HSPB6 | 0.880148 | 3 | 0 | 3 |
| CLEC3B | F10 | 0.876247 | 3 | 0 | 3 |
| CLEC3B | SORCS1 | 0.876006 | 3 | 0 | 3 |
| CLEC3B | ITGA8 | 0.873528 | 3 | 0 | 3 |
| CLEC3B | FHL5 | 0.869156 | 3 | 0 | 3 |
| CLEC3B | C1QTNF7 | 0.865598 | 3 | 0 | 3 |
| CLEC3B | ATP1A2 | 0.863577 | 3 | 0 | 3 |
| CLEC3B | HLF | 0.863476 | 3 | 0 | 3 |
| CLEC3B | NFIA | 0.861517 | 3 | 0 | 3 |
| CLEC3B | MFAP4 | 0.859232 | 3 | 0 | 3 |
For details and further investigation, click here
