| Full name: SEC23 interacting protein | Alias Symbol: p125 | ||
| Type: protein-coding gene | Cytoband: 10q26.11-q26.12 | ||
| Entrez ID: 11196 | HGNC ID: HGNC:17018 | Ensembl Gene: ENSG00000107651 | OMIM ID: 617852 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SEC23IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC23IP | 11196 | 216392_s_at | -0.2061 | 0.5537 | |
| GSE20347 | SEC23IP | 11196 | 209175_at | 0.0832 | 0.6701 | |
| GSE23400 | SEC23IP | 11196 | 216392_s_at | 0.1151 | 0.0242 | |
| GSE26886 | SEC23IP | 11196 | 209175_at | -0.8629 | 0.0027 | |
| GSE29001 | SEC23IP | 11196 | 209176_at | -0.0672 | 0.7258 | |
| GSE38129 | SEC23IP | 11196 | 209175_at | 0.1624 | 0.2802 | |
| GSE45670 | SEC23IP | 11196 | 209175_at | 0.0253 | 0.8915 | |
| GSE53622 | SEC23IP | 11196 | 23642 | 0.0622 | 0.3562 | |
| GSE53624 | SEC23IP | 11196 | 23642 | 0.0609 | 0.5465 | |
| GSE63941 | SEC23IP | 11196 | 216392_s_at | -0.0715 | 0.8113 | |
| GSE77861 | SEC23IP | 11196 | 216392_s_at | 0.0428 | 0.8544 | |
| GSE97050 | SEC23IP | 11196 | A_23_P202602 | 0.2428 | 0.3926 | |
| SRP007169 | SEC23IP | 11196 | RNAseq | 0.1419 | 0.6898 | |
| SRP008496 | SEC23IP | 11196 | RNAseq | 0.2572 | 0.2709 | |
| SRP064894 | SEC23IP | 11196 | RNAseq | -0.0053 | 0.9721 | |
| SRP133303 | SEC23IP | 11196 | RNAseq | 0.1911 | 0.0270 | |
| SRP159526 | SEC23IP | 11196 | RNAseq | -0.2135 | 0.4940 | |
| SRP193095 | SEC23IP | 11196 | RNAseq | -0.0656 | 0.5312 | |
| SRP219564 | SEC23IP | 11196 | RNAseq | 0.1415 | 0.5258 | |
| TCGA | SEC23IP | 11196 | RNAseq | -0.2162 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEC23IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC23IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC23IP | 11196 | 2 | 8 | 20 | |
| GSE20123 | SEC23IP | 11196 | 2 | 8 | 20 | |
| GSE43470 | SEC23IP | 11196 | 0 | 9 | 34 | |
| GSE46452 | SEC23IP | 11196 | 0 | 11 | 48 | |
| GSE47630 | SEC23IP | 11196 | 2 | 14 | 24 | |
| GSE54993 | SEC23IP | 11196 | 8 | 0 | 62 | |
| GSE54994 | SEC23IP | 11196 | 1 | 9 | 43 | |
| GSE60625 | SEC23IP | 11196 | 0 | 0 | 11 | |
| GSE74703 | SEC23IP | 11196 | 0 | 6 | 30 | |
| GSE74704 | SEC23IP | 11196 | 1 | 3 | 16 | |
| TCGA | SEC23IP | 11196 | 4 | 28 | 64 |
Total number of gains: 20; Total number of losses: 96; Total Number of normals: 372.
Somatic mutations of SEC23IP:
Generating mutation plots.
Highly correlated genes for SEC23IP:
Showing top 20/556 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC23IP | HIPK1 | 0.798052 | 3 | 0 | 3 |
| SEC23IP | SAMD8 | 0.767543 | 3 | 0 | 3 |
| SEC23IP | SENP3 | 0.76742 | 3 | 0 | 3 |
| SEC23IP | PRKAB1 | 0.749071 | 3 | 0 | 3 |
| SEC23IP | SWAP70 | 0.748144 | 3 | 0 | 3 |
| SEC23IP | FYTTD1 | 0.74274 | 3 | 0 | 3 |
| SEC23IP | LMO2 | 0.726894 | 3 | 0 | 3 |
| SEC23IP | CTTNBP2NL | 0.718707 | 4 | 0 | 4 |
| SEC23IP | ZDHHC3 | 0.716563 | 3 | 0 | 3 |
| SEC23IP | ARPC2 | 0.714573 | 3 | 0 | 3 |
| SEC23IP | PPCS | 0.709615 | 3 | 0 | 3 |
| SEC23IP | PI4K2B | 0.701436 | 3 | 0 | 3 |
| SEC23IP | PAIP2 | 0.697005 | 3 | 0 | 3 |
| SEC23IP | AHCY | 0.687962 | 3 | 0 | 3 |
| SEC23IP | TIA1 | 0.686771 | 3 | 0 | 3 |
| SEC23IP | TUBGCP4 | 0.686548 | 3 | 0 | 3 |
| SEC23IP | MTUS1 | 0.683752 | 4 | 0 | 3 |
| SEC23IP | TAB3 | 0.683368 | 3 | 0 | 3 |
| SEC23IP | TMX3 | 0.679454 | 3 | 0 | 3 |
| SEC23IP | ETF1 | 0.677533 | 3 | 0 | 3 |
For details and further investigation, click here
