| Full name: recombination signal binding protein for immunoglobulin kappa J region like | Alias Symbol: RBP-L|SUH|SUHL | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 11317 | HGNC ID: HGNC:13761 | Ensembl Gene: ENSG00000124232 | OMIM ID: 616104 |
| Drug and gene relationship at DGIdb | |||
RBPJL involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04330 | Notch signaling pathway | |
| hsa05169 | Epstein-Barr virus infection |
Expression of RBPJL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBPJL | 11317 | 221377_s_at | -0.1090 | 0.5725 | |
| GSE20347 | RBPJL | 11317 | 221377_s_at | -0.0724 | 0.3867 | |
| GSE23400 | RBPJL | 11317 | 221377_s_at | -0.0624 | 0.0297 | |
| GSE26886 | RBPJL | 11317 | 221377_s_at | 0.0194 | 0.8695 | |
| GSE29001 | RBPJL | 11317 | 221377_s_at | -0.1394 | 0.2221 | |
| GSE38129 | RBPJL | 11317 | 221377_s_at | -0.1133 | 0.0787 | |
| GSE45670 | RBPJL | 11317 | 221377_s_at | -0.0362 | 0.7364 | |
| GSE53622 | RBPJL | 11317 | 27283 | -0.0931 | 0.5540 | |
| GSE53624 | RBPJL | 11317 | 27283 | -0.2607 | 0.1072 | |
| GSE63941 | RBPJL | 11317 | 221377_s_at | 0.1757 | 0.2319 | |
| GSE77861 | RBPJL | 11317 | 221377_s_at | -0.1135 | 0.2142 | |
| GSE97050 | RBPJL | 11317 | A_23_P346884 | -0.2036 | 0.5534 | |
| TCGA | RBPJL | 11317 | RNAseq | -4.2846 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RBPJL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBPJL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBPJL | 11317 | 13 | 1 | 16 | |
| GSE20123 | RBPJL | 11317 | 13 | 1 | 16 | |
| GSE43470 | RBPJL | 11317 | 12 | 1 | 30 | |
| GSE46452 | RBPJL | 11317 | 29 | 0 | 30 | |
| GSE47630 | RBPJL | 11317 | 24 | 1 | 15 | |
| GSE54993 | RBPJL | 11317 | 0 | 17 | 53 | |
| GSE54994 | RBPJL | 11317 | 25 | 0 | 28 | |
| GSE60625 | RBPJL | 11317 | 0 | 0 | 11 | |
| GSE74703 | RBPJL | 11317 | 10 | 1 | 25 | |
| GSE74704 | RBPJL | 11317 | 9 | 0 | 11 | |
| TCGA | RBPJL | 11317 | 45 | 3 | 48 |
Total number of gains: 180; Total number of losses: 25; Total Number of normals: 283.
Somatic mutations of RBPJL:
Generating mutation plots.
Highly correlated genes for RBPJL:
Showing top 20/765 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBPJL | ALKBH7 | 0.794082 | 3 | 0 | 3 |
| RBPJL | ZDHHC3 | 0.784893 | 3 | 0 | 3 |
| RBPJL | TPRG1L | 0.780167 | 3 | 0 | 3 |
| RBPJL | ZFAND2B | 0.770788 | 3 | 0 | 3 |
| RBPJL | MSRA | 0.767189 | 3 | 0 | 3 |
| RBPJL | SREBF2 | 0.75582 | 4 | 0 | 4 |
| RBPJL | VPS37B | 0.752325 | 3 | 0 | 3 |
| RBPJL | ZNF358 | 0.749827 | 3 | 0 | 3 |
| RBPJL | AKR7A2 | 0.747326 | 3 | 0 | 3 |
| RBPJL | PITHD1 | 0.746394 | 3 | 0 | 3 |
| RBPJL | PPCS | 0.74164 | 3 | 0 | 3 |
| RBPJL | DUSP22 | 0.73581 | 4 | 0 | 4 |
| RBPJL | CRYL1 | 0.730672 | 3 | 0 | 3 |
| RBPJL | TWF2 | 0.728815 | 3 | 0 | 3 |
| RBPJL | MKRN2 | 0.724447 | 3 | 0 | 3 |
| RBPJL | KIR3DL2 | 0.721079 | 3 | 0 | 3 |
| RBPJL | MTUS2-AS1 | 0.721013 | 3 | 0 | 3 |
| RBPJL | COMTD1 | 0.716367 | 4 | 0 | 4 |
| RBPJL | POLR2L | 0.714889 | 4 | 0 | 3 |
| RBPJL | HCFC2 | 0.714155 | 3 | 0 | 3 |
For details and further investigation, click here
