| Full name: zinc finger MIZ-type containing 1 | Alias Symbol: RP11-519K18.1|KIAA1224|FLJ13541|hZIMP10|Zimp10|MIZ | ||
| Type: protein-coding gene | Cytoband: 10q22.3 | ||
| Entrez ID: 57178 | HGNC ID: HGNC:16493 | Ensembl Gene: ENSG00000108175 | OMIM ID: 607159 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZMIZ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZMIZ1 | 57178 | 212124_at | -0.8848 | 0.0488 | |
| GSE20347 | ZMIZ1 | 57178 | 212124_at | -0.5267 | 0.0044 | |
| GSE23400 | ZMIZ1 | 57178 | 212124_at | -0.5264 | 0.0000 | |
| GSE26886 | ZMIZ1 | 57178 | 212124_at | -0.3121 | 0.3002 | |
| GSE29001 | ZMIZ1 | 57178 | 212124_at | -0.4917 | 0.1087 | |
| GSE38129 | ZMIZ1 | 57178 | 212124_at | -0.4688 | 0.0005 | |
| GSE45670 | ZMIZ1 | 57178 | 212124_at | -0.4694 | 0.0001 | |
| GSE53622 | ZMIZ1 | 57178 | 37260 | -0.6492 | 0.0000 | |
| GSE53624 | ZMIZ1 | 57178 | 37260 | -0.5546 | 0.0000 | |
| GSE63941 | ZMIZ1 | 57178 | 212124_at | -1.6318 | 0.0474 | |
| GSE77861 | ZMIZ1 | 57178 | 212124_at | -0.1680 | 0.5937 | |
| GSE97050 | ZMIZ1 | 57178 | A_23_P138435 | -0.6395 | 0.0866 | |
| SRP007169 | ZMIZ1 | 57178 | RNAseq | -0.0303 | 0.9502 | |
| SRP008496 | ZMIZ1 | 57178 | RNAseq | 0.1215 | 0.7142 | |
| SRP064894 | ZMIZ1 | 57178 | RNAseq | -0.8460 | 0.0017 | |
| SRP133303 | ZMIZ1 | 57178 | RNAseq | -0.2826 | 0.1895 | |
| SRP159526 | ZMIZ1 | 57178 | RNAseq | -1.1353 | 0.0014 | |
| SRP193095 | ZMIZ1 | 57178 | RNAseq | -0.1512 | 0.3170 | |
| SRP219564 | ZMIZ1 | 57178 | RNAseq | -0.9943 | 0.0201 | |
| TCGA | ZMIZ1 | 57178 | RNAseq | -0.1009 | 0.0177 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ZMIZ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZMIZ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZMIZ1 | 57178 | 2 | 5 | 23 | |
| GSE20123 | ZMIZ1 | 57178 | 2 | 4 | 24 | |
| GSE43470 | ZMIZ1 | 57178 | 1 | 7 | 35 | |
| GSE46452 | ZMIZ1 | 57178 | 0 | 11 | 48 | |
| GSE47630 | ZMIZ1 | 57178 | 2 | 14 | 24 | |
| GSE54993 | ZMIZ1 | 57178 | 7 | 0 | 63 | |
| GSE54994 | ZMIZ1 | 57178 | 1 | 11 | 41 | |
| GSE60625 | ZMIZ1 | 57178 | 0 | 0 | 11 | |
| GSE74703 | ZMIZ1 | 57178 | 1 | 4 | 31 | |
| GSE74704 | ZMIZ1 | 57178 | 1 | 2 | 17 | |
| TCGA | ZMIZ1 | 57178 | 10 | 24 | 62 |
Total number of gains: 27; Total number of losses: 82; Total Number of normals: 379.
Somatic mutations of ZMIZ1:
Generating mutation plots.
Highly correlated genes for ZMIZ1:
Showing top 20/931 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZMIZ1 | CCNDBP1 | 0.770759 | 4 | 0 | 4 |
| ZMIZ1 | ANKRD37 | 0.769627 | 3 | 0 | 3 |
| ZMIZ1 | IDH3G | 0.762454 | 3 | 0 | 3 |
| ZMIZ1 | TMEM109 | 0.759811 | 3 | 0 | 3 |
| ZMIZ1 | PDE8B | 0.754776 | 3 | 0 | 3 |
| ZMIZ1 | VPS25 | 0.725446 | 3 | 0 | 3 |
| ZMIZ1 | TMEM19 | 0.723786 | 3 | 0 | 3 |
| ZMIZ1 | CETN2 | 0.714443 | 3 | 0 | 3 |
| ZMIZ1 | ZNF528 | 0.707628 | 3 | 0 | 3 |
| ZMIZ1 | LIFR | 0.704906 | 4 | 0 | 4 |
| ZMIZ1 | NTAN1 | 0.704321 | 3 | 0 | 3 |
| ZMIZ1 | PRKCA | 0.70334 | 3 | 0 | 3 |
| ZMIZ1 | RNF14 | 0.701643 | 3 | 0 | 3 |
| ZMIZ1 | C1orf50 | 0.700611 | 3 | 0 | 3 |
| ZMIZ1 | C2orf42 | 0.699173 | 3 | 0 | 3 |
| ZMIZ1 | RHOBTB2 | 0.697033 | 3 | 0 | 3 |
| ZMIZ1 | SLITRK4 | 0.696974 | 3 | 0 | 3 |
| ZMIZ1 | PAQR8 | 0.69647 | 5 | 0 | 4 |
| ZMIZ1 | KCTD6 | 0.696418 | 5 | 0 | 5 |
| ZMIZ1 | SLC46A2 | 0.692712 | 5 | 0 | 4 |
For details and further investigation, click here
