| Full name: Rho related BTB domain containing 2 | Alias Symbol: KIAA0717|DBC2 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 23221 | HGNC ID: HGNC:18756 | Ensembl Gene: ENSG00000008853 | OMIM ID: 607352 |
| Drug and gene relationship at DGIdb | |||
Expression of RHOBTB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHOBTB2 | 23221 | 209441_at | 0.0692 | 0.8113 | |
| GSE20347 | RHOBTB2 | 23221 | 209441_at | 0.1146 | 0.2618 | |
| GSE23400 | RHOBTB2 | 23221 | 209441_at | -0.0427 | 0.1922 | |
| GSE26886 | RHOBTB2 | 23221 | 209441_at | 0.5047 | 0.0004 | |
| GSE29001 | RHOBTB2 | 23221 | 209441_at | 0.0040 | 0.9781 | |
| GSE38129 | RHOBTB2 | 23221 | 209441_at | -0.1976 | 0.0918 | |
| GSE45670 | RHOBTB2 | 23221 | 209441_at | -0.0492 | 0.5727 | |
| GSE53622 | RHOBTB2 | 23221 | 43833 | 0.1214 | 0.3125 | |
| GSE53624 | RHOBTB2 | 23221 | 43833 | 0.3002 | 0.0003 | |
| GSE63941 | RHOBTB2 | 23221 | 209441_at | -0.7409 | 0.0262 | |
| GSE77861 | RHOBTB2 | 23221 | 209441_at | 0.0928 | 0.5658 | |
| GSE97050 | RHOBTB2 | 23221 | A_23_P20427 | -0.1175 | 0.7046 | |
| SRP007169 | RHOBTB2 | 23221 | RNAseq | 1.4740 | 0.0136 | |
| SRP008496 | RHOBTB2 | 23221 | RNAseq | 1.8734 | 0.0001 | |
| SRP064894 | RHOBTB2 | 23221 | RNAseq | 0.7452 | 0.0007 | |
| SRP133303 | RHOBTB2 | 23221 | RNAseq | -0.0025 | 0.9914 | |
| SRP159526 | RHOBTB2 | 23221 | RNAseq | 0.8040 | 0.0820 | |
| SRP193095 | RHOBTB2 | 23221 | RNAseq | 0.5128 | 0.0455 | |
| SRP219564 | RHOBTB2 | 23221 | RNAseq | 0.7702 | 0.2870 | |
| TCGA | RHOBTB2 | 23221 | RNAseq | -0.4181 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RHOBTB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHOBTB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHOBTB2 | 23221 | 4 | 10 | 16 | |
| GSE20123 | RHOBTB2 | 23221 | 4 | 10 | 16 | |
| GSE43470 | RHOBTB2 | 23221 | 4 | 9 | 30 | |
| GSE46452 | RHOBTB2 | 23221 | 13 | 13 | 33 | |
| GSE47630 | RHOBTB2 | 23221 | 10 | 8 | 22 | |
| GSE54993 | RHOBTB2 | 23221 | 2 | 14 | 54 | |
| GSE54994 | RHOBTB2 | 23221 | 8 | 18 | 27 | |
| GSE60625 | RHOBTB2 | 23221 | 3 | 0 | 8 | |
| GSE74703 | RHOBTB2 | 23221 | 4 | 7 | 25 | |
| GSE74704 | RHOBTB2 | 23221 | 3 | 7 | 10 | |
| TCGA | RHOBTB2 | 23221 | 14 | 43 | 39 |
Total number of gains: 69; Total number of losses: 139; Total Number of normals: 280.
Somatic mutations of RHOBTB2:
Generating mutation plots.
Highly correlated genes for RHOBTB2:
Showing top 20/813 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHOBTB2 | RFTN2 | 0.78108 | 3 | 0 | 3 |
| RHOBTB2 | TRIM47 | 0.7726 | 3 | 0 | 3 |
| RHOBTB2 | DNAJC11 | 0.761442 | 3 | 0 | 3 |
| RHOBTB2 | GALNT6 | 0.75805 | 3 | 0 | 3 |
| RHOBTB2 | SETD1A | 0.755187 | 3 | 0 | 3 |
| RHOBTB2 | GTPBP10 | 0.754906 | 3 | 0 | 3 |
| RHOBTB2 | LENG8 | 0.732963 | 3 | 0 | 3 |
| RHOBTB2 | MPG | 0.732256 | 3 | 0 | 3 |
| RHOBTB2 | ITGA8 | 0.731514 | 4 | 0 | 4 |
| RHOBTB2 | SYNC | 0.730639 | 3 | 0 | 3 |
| RHOBTB2 | CISH | 0.729832 | 3 | 0 | 3 |
| RHOBTB2 | VAC14 | 0.728951 | 3 | 0 | 3 |
| RHOBTB2 | FRY | 0.723207 | 3 | 0 | 3 |
| RHOBTB2 | SGCA | 0.722202 | 4 | 0 | 3 |
| RHOBTB2 | MMP15 | 0.720058 | 4 | 0 | 3 |
| RHOBTB2 | TSHZ3 | 0.718041 | 5 | 0 | 5 |
| RHOBTB2 | SERPINF2 | 0.715816 | 4 | 0 | 4 |
| RHOBTB2 | GSTO1 | 0.715052 | 3 | 0 | 3 |
| RHOBTB2 | KIAA0895L | 0.713371 | 3 | 0 | 3 |
| RHOBTB2 | SNAPC4 | 0.712894 | 3 | 0 | 3 |
For details and further investigation, click here
