| Full name: transmembrane protein 109 | Alias Symbol: MGC5508 | ||
| Type: protein-coding gene | Cytoband: 11q12.2 | ||
| Entrez ID: 79073 | HGNC ID: HGNC:28771 | Ensembl Gene: ENSG00000110108 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM109:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM109 | 79073 | 201361_at | -0.2398 | 0.3715 | |
| GSE20347 | TMEM109 | 79073 | 201361_at | -0.2036 | 0.2286 | |
| GSE23400 | TMEM109 | 79073 | 201361_at | -0.1935 | 0.0012 | |
| GSE26886 | TMEM109 | 79073 | 201361_at | -0.5808 | 0.0071 | |
| GSE29001 | TMEM109 | 79073 | 201361_at | -0.2991 | 0.3489 | |
| GSE38129 | TMEM109 | 79073 | 201361_at | -0.3119 | 0.0077 | |
| GSE45670 | TMEM109 | 79073 | 201361_at | -0.3718 | 0.0121 | |
| GSE53622 | TMEM109 | 79073 | 36429 | -0.4947 | 0.0000 | |
| GSE53624 | TMEM109 | 79073 | 36429 | -0.1328 | 0.0428 | |
| GSE63941 | TMEM109 | 79073 | 201361_at | -0.9602 | 0.0612 | |
| GSE77861 | TMEM109 | 79073 | 201361_at | 0.0325 | 0.8782 | |
| GSE97050 | TMEM109 | 79073 | A_24_P47467 | -0.5930 | 0.0832 | |
| SRP007169 | TMEM109 | 79073 | RNAseq | -0.7817 | 0.0130 | |
| SRP008496 | TMEM109 | 79073 | RNAseq | -0.7512 | 0.0023 | |
| SRP064894 | TMEM109 | 79073 | RNAseq | -0.3654 | 0.0430 | |
| SRP133303 | TMEM109 | 79073 | RNAseq | -0.2853 | 0.2158 | |
| SRP159526 | TMEM109 | 79073 | RNAseq | -0.2125 | 0.4406 | |
| SRP193095 | TMEM109 | 79073 | RNAseq | -0.0248 | 0.8907 | |
| SRP219564 | TMEM109 | 79073 | RNAseq | -0.1621 | 0.6978 | |
| TCGA | TMEM109 | 79073 | RNAseq | 0.0539 | 0.2506 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM109 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM109:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM109 | 79073 | 2 | 5 | 23 | |
| GSE20123 | TMEM109 | 79073 | 2 | 5 | 23 | |
| GSE43470 | TMEM109 | 79073 | 2 | 6 | 35 | |
| GSE46452 | TMEM109 | 79073 | 8 | 4 | 47 | |
| GSE47630 | TMEM109 | 79073 | 3 | 8 | 29 | |
| GSE54993 | TMEM109 | 79073 | 3 | 0 | 67 | |
| GSE54994 | TMEM109 | 79073 | 5 | 5 | 43 | |
| GSE60625 | TMEM109 | 79073 | 0 | 3 | 8 | |
| GSE74703 | TMEM109 | 79073 | 2 | 3 | 31 | |
| GSE74704 | TMEM109 | 79073 | 2 | 3 | 15 | |
| TCGA | TMEM109 | 79073 | 15 | 10 | 71 |
Total number of gains: 44; Total number of losses: 52; Total Number of normals: 392.
Somatic mutations of TMEM109:
Generating mutation plots.
Highly correlated genes for TMEM109:
Showing top 20/571 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM109 | ZMIZ1 | 0.759811 | 3 | 0 | 3 |
| TMEM109 | STXBP3 | 0.730124 | 3 | 0 | 3 |
| TMEM109 | PCBP2 | 0.717619 | 3 | 0 | 3 |
| TMEM109 | RAB5A | 0.717554 | 3 | 0 | 3 |
| TMEM109 | NCOR1 | 0.715843 | 3 | 0 | 3 |
| TMEM109 | COX5A | 0.707696 | 3 | 0 | 3 |
| TMEM109 | SORT1 | 0.705189 | 4 | 0 | 4 |
| TMEM109 | FBXW5 | 0.701155 | 5 | 0 | 4 |
| TMEM109 | OCRL | 0.700286 | 3 | 0 | 3 |
| TMEM109 | USP25 | 0.699723 | 3 | 0 | 3 |
| TMEM109 | ARL1 | 0.694757 | 4 | 0 | 4 |
| TMEM109 | YIPF3 | 0.694182 | 3 | 0 | 3 |
| TMEM109 | FGD4 | 0.685681 | 3 | 0 | 3 |
| TMEM109 | MORC3 | 0.683058 | 3 | 0 | 3 |
| TMEM109 | DPP8 | 0.681479 | 3 | 0 | 3 |
| TMEM109 | ATG7 | 0.681361 | 3 | 0 | 3 |
| TMEM109 | GGA3 | 0.680498 | 3 | 0 | 3 |
| TMEM109 | ZMYND11 | 0.679542 | 3 | 0 | 3 |
| TMEM109 | SERF2 | 0.679291 | 3 | 0 | 3 |
| TMEM109 | CGNL1 | 0.678181 | 4 | 0 | 3 |
For details and further investigation, click here
