| Full name: chromosome 1 open reading frame 50 | Alias Symbol: MGC955 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 79078 | HGNC ID: HGNC:28795 | Ensembl Gene: ENSG00000164008 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C1orf50:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1orf50 | 79078 | 219406_at | 0.0350 | 0.9437 | |
| GSE20347 | C1orf50 | 79078 | 219406_at | -0.1066 | 0.4666 | |
| GSE23400 | C1orf50 | 79078 | 219406_at | 0.0873 | 0.0892 | |
| GSE26886 | C1orf50 | 79078 | 219406_at | 0.5995 | 0.0195 | |
| GSE29001 | C1orf50 | 79078 | 219406_at | -0.0680 | 0.8391 | |
| GSE38129 | C1orf50 | 79078 | 219406_at | -0.0588 | 0.5697 | |
| GSE45670 | C1orf50 | 79078 | 219406_at | 0.2173 | 0.0724 | |
| GSE53622 | C1orf50 | 79078 | 49016 | 0.0276 | 0.7527 | |
| GSE53624 | C1orf50 | 79078 | 49016 | 0.1056 | 0.2764 | |
| GSE63941 | C1orf50 | 79078 | 219406_at | -0.3575 | 0.3275 | |
| GSE77861 | C1orf50 | 79078 | 219406_at | -0.1735 | 0.5503 | |
| GSE97050 | C1orf50 | 79078 | A_23_P74435 | 0.0844 | 0.7036 | |
| SRP007169 | C1orf50 | 79078 | RNAseq | -0.7615 | 0.0802 | |
| SRP008496 | C1orf50 | 79078 | RNAseq | -0.5532 | 0.1013 | |
| SRP064894 | C1orf50 | 79078 | RNAseq | 0.3666 | 0.1273 | |
| SRP133303 | C1orf50 | 79078 | RNAseq | -0.0622 | 0.6109 | |
| SRP159526 | C1orf50 | 79078 | RNAseq | 0.3904 | 0.4594 | |
| SRP193095 | C1orf50 | 79078 | RNAseq | -0.0973 | 0.3535 | |
| SRP219564 | C1orf50 | 79078 | RNAseq | 0.1945 | 0.5720 | |
| TCGA | C1orf50 | 79078 | RNAseq | 0.0000 | 0.9997 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C1orf50 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1orf50:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1orf50 | 79078 | 4 | 3 | 23 | |
| GSE20123 | C1orf50 | 79078 | 3 | 2 | 25 | |
| GSE43470 | C1orf50 | 79078 | 7 | 2 | 34 | |
| GSE46452 | C1orf50 | 79078 | 3 | 1 | 55 | |
| GSE47630 | C1orf50 | 79078 | 9 | 2 | 29 | |
| GSE54993 | C1orf50 | 79078 | 0 | 2 | 68 | |
| GSE54994 | C1orf50 | 79078 | 14 | 2 | 37 | |
| GSE60625 | C1orf50 | 79078 | 0 | 0 | 11 | |
| GSE74703 | C1orf50 | 79078 | 6 | 1 | 29 | |
| GSE74704 | C1orf50 | 79078 | 1 | 0 | 19 | |
| TCGA | C1orf50 | 79078 | 13 | 16 | 67 |
Total number of gains: 60; Total number of losses: 31; Total Number of normals: 397.
Somatic mutations of C1orf50:
Generating mutation plots.
Highly correlated genes for C1orf50:
Showing top 20/400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1orf50 | CEP57 | 0.821652 | 3 | 0 | 3 |
| C1orf50 | COG1 | 0.805717 | 3 | 0 | 3 |
| C1orf50 | ZNF764 | 0.795075 | 3 | 0 | 3 |
| C1orf50 | ZNF766 | 0.773993 | 3 | 0 | 3 |
| C1orf50 | TDP2 | 0.760941 | 3 | 0 | 3 |
| C1orf50 | PIGH | 0.759432 | 5 | 0 | 5 |
| C1orf50 | ELP3 | 0.757437 | 3 | 0 | 3 |
| C1orf50 | UHRF1BP1 | 0.754464 | 3 | 0 | 3 |
| C1orf50 | ESCO1 | 0.752063 | 3 | 0 | 3 |
| C1orf50 | SYNE2 | 0.751319 | 3 | 0 | 3 |
| C1orf50 | ISY1 | 0.742414 | 3 | 0 | 3 |
| C1orf50 | ZFYVE26 | 0.742231 | 5 | 0 | 5 |
| C1orf50 | ZNF121 | 0.740934 | 3 | 0 | 3 |
| C1orf50 | ATG2B | 0.739477 | 3 | 0 | 3 |
| C1orf50 | BTBD6 | 0.736846 | 4 | 0 | 4 |
| C1orf50 | GPATCH1 | 0.73549 | 3 | 0 | 3 |
| C1orf50 | ACVR1B | 0.729607 | 3 | 0 | 3 |
| C1orf50 | INPP5B | 0.728655 | 6 | 0 | 6 |
| C1orf50 | MED26 | 0.723316 | 4 | 0 | 3 |
| C1orf50 | EIF2B2 | 0.718377 | 5 | 0 | 5 |
For details and further investigation, click here
