| Full name: solute carrier family 46 member 2 | Alias Symbol: Ly110 | ||
| Type: protein-coding gene | Cytoband: 9q32 | ||
| Entrez ID: 57864 | HGNC ID: HGNC:16055 | Ensembl Gene: ENSG00000119457 | OMIM ID: 608956 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC46A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC46A2 | 57864 | 223816_at | -0.8404 | 0.1378 | |
| GSE26886 | SLC46A2 | 57864 | 223816_at | -1.0729 | 0.0000 | |
| GSE45670 | SLC46A2 | 57864 | 223816_at | -0.6706 | 0.0152 | |
| GSE53622 | SLC46A2 | 57864 | 123798 | -2.8887 | 0.0000 | |
| GSE53624 | SLC46A2 | 57864 | 123798 | -3.5421 | 0.0000 | |
| GSE63941 | SLC46A2 | 57864 | 223816_at | 0.0902 | 0.5643 | |
| GSE77861 | SLC46A2 | 57864 | 223816_at | -0.5131 | 0.0020 | |
| GSE97050 | SLC46A2 | 57864 | A_23_P31996 | -0.4460 | 0.1833 | |
| SRP007169 | SLC46A2 | 57864 | RNAseq | -4.5404 | 0.0000 | |
| SRP064894 | SLC46A2 | 57864 | RNAseq | -1.9765 | 0.0000 | |
| SRP133303 | SLC46A2 | 57864 | RNAseq | -1.8778 | 0.0000 | |
| SRP159526 | SLC46A2 | 57864 | RNAseq | -1.4509 | 0.0186 | |
| TCGA | SLC46A2 | 57864 | RNAseq | -0.1496 | 0.6576 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by SLC46A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC46A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC46A2 | 57864 | 5 | 10 | 15 | |
| GSE20123 | SLC46A2 | 57864 | 5 | 10 | 15 | |
| GSE43470 | SLC46A2 | 57864 | 4 | 3 | 36 | |
| GSE46452 | SLC46A2 | 57864 | 6 | 13 | 40 | |
| GSE47630 | SLC46A2 | 57864 | 3 | 16 | 21 | |
| GSE54993 | SLC46A2 | 57864 | 3 | 3 | 64 | |
| GSE54994 | SLC46A2 | 57864 | 9 | 10 | 34 | |
| GSE60625 | SLC46A2 | 57864 | 0 | 0 | 11 | |
| GSE74703 | SLC46A2 | 57864 | 4 | 3 | 29 | |
| GSE74704 | SLC46A2 | 57864 | 2 | 8 | 10 | |
| TCGA | SLC46A2 | 57864 | 26 | 22 | 48 |
Total number of gains: 67; Total number of losses: 98; Total Number of normals: 323.
Somatic mutations of SLC46A2:
Generating mutation plots.
Highly correlated genes for SLC46A2:
Showing top 20/1750 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC46A2 | GYS2 | 0.874044 | 6 | 0 | 6 |
| SLC46A2 | GDPD3 | 0.870307 | 6 | 0 | 6 |
| SLC46A2 | TP53I3 | 0.86168 | 6 | 0 | 6 |
| SLC46A2 | KRT78 | 0.859928 | 6 | 0 | 6 |
| SLC46A2 | SFTA2 | 0.859583 | 4 | 0 | 4 |
| SLC46A2 | ECM1 | 0.853118 | 6 | 0 | 6 |
| SLC46A2 | SLC16A6 | 0.85289 | 7 | 0 | 7 |
| SLC46A2 | FAM3D | 0.848729 | 6 | 0 | 6 |
| SLC46A2 | HCG22 | 0.84677 | 6 | 0 | 6 |
| SLC46A2 | CYSRT1 | 0.846642 | 6 | 0 | 6 |
| SLC46A2 | SCNN1B | 0.843381 | 6 | 0 | 6 |
| SLC46A2 | RMND5B | 0.841232 | 7 | 0 | 7 |
| SLC46A2 | TMEM40 | 0.840423 | 6 | 0 | 6 |
| SLC46A2 | DOCK9 | 0.836443 | 7 | 0 | 7 |
| SLC46A2 | A2ML1 | 0.836084 | 6 | 0 | 6 |
| SLC46A2 | ULK3 | 0.833747 | 7 | 0 | 7 |
| SLC46A2 | EPS8L1 | 0.833642 | 6 | 0 | 6 |
| SLC46A2 | CXCR2 | 0.832488 | 7 | 0 | 7 |
| SLC46A2 | ACPP | 0.831621 | 6 | 0 | 6 |
| SLC46A2 | ABHD5 | 0.831287 | 7 | 0 | 7 |
For details and further investigation, click here
