ZNF18

 

Full name: zinc finger protein 18 Alias Symbol: ZKSCAN6|KOX11|HDSG1|Zfp535|ZNF535|ZSCAN38
Type: protein-coding gene Cytoband: 17p12
Entrez ID: 7566 HGNC ID: HGNC:12969 Ensembl Gene: ENSG00000154957 OMIM ID: 194524
Drug and gene relationship at DGIdb

 

Expression of ZNF18:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF18 7566 226787_at 0.0852 0.7383
GSE26886 ZNF18 7566 226787_at 0.5870 0.0178
GSE45670 ZNF18 7566 226787_at 0.2795 0.0158
GSE53622 ZNF18 7566 39283 0.2948 0.0001
GSE53624 ZNF18 7566 39283 0.2662 0.0000
GSE63941 ZNF18 7566 226787_at -0.4222 0.3327
GSE77861 ZNF18 7566 226787_at 0.3652 0.0577
GSE97050 ZNF18 7566 A_23_P141302 0.0656 0.7546
SRP007169 ZNF18 7566 RNAseq -0.1761 0.6661
SRP008496 ZNF18 7566 RNAseq 0.1064 0.6841
SRP064894 ZNF18 7566 RNAseq 0.8334 0.0001
SRP133303 ZNF18 7566 RNAseq 0.0893 0.5765
SRP159526 ZNF18 7566 RNAseq 0.0982 0.7509
SRP193095 ZNF18 7566 RNAseq 0.1371 0.1933
SRP219564 ZNF18 7566 RNAseq 0.8095 0.0591
TCGA ZNF18 7566 RNAseq 0.0989 0.1297

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by ZNF18 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF18:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF18 7566 3 4 23
GSE20123 ZNF18 7566 3 5 22
GSE43470 ZNF18 7566 2 5 36
GSE46452 ZNF18 7566 34 1 24
GSE47630 ZNF18 7566 7 1 32
GSE54993 ZNF18 7566 3 2 65
GSE54994 ZNF18 7566 6 6 41
GSE60625 ZNF18 7566 4 0 7
GSE74703 ZNF18 7566 2 4 30
GSE74704 ZNF18 7566 2 2 16
TCGA ZNF18 7566 18 21 57

Total number of gains: 84; Total number of losses: 51; Total Number of normals: 353.  


 

Somatic mutations of ZNF18:

 

Generating mutation plots.

 

Highly correlated genes for ZNF18:

 

Showing top 20/621 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF18TLR10.779972303
ZNF18ZNF3220.768486303
ZNF18C20orf1940.756376303
ZNF18IL13RA20.751357303
ZNF18ATP11C0.751082303
ZNF18HAUS10.747257303
ZNF18SH2B30.746883303
ZNF18RNF144A0.745207303
ZNF18TMEM185B0.735914404
ZNF18HCFC10.732831303
ZNF18FAM20B0.732773303
ZNF18PTPRJ0.732739303
ZNF18CD930.731694303
ZNF18TOR1A0.725414303
ZNF18UVRAG0.721816303
ZNF18PSPC10.721595404
ZNF18PJA10.716761404
ZNF18PSMA50.71494303
ZNF18BORA0.710351303
ZNF18EID20.708745303

For details and further investigation, click here