| Full name: proteasome subunit alpha 5 | Alias Symbol: ZETA | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 5686 | HGNC ID: HGNC:9534 | Ensembl Gene: ENSG00000143106 | OMIM ID: 176844 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMA5 | 5686 | 201274_at | 0.1912 | 0.6816 | |
| GSE20347 | PSMA5 | 5686 | 201274_at | -0.0093 | 0.9679 | |
| GSE23400 | PSMA5 | 5686 | 201274_at | 0.2982 | 0.0000 | |
| GSE26886 | PSMA5 | 5686 | 201274_at | 0.0761 | 0.7674 | |
| GSE29001 | PSMA5 | 5686 | 201274_at | 0.0534 | 0.9018 | |
| GSE38129 | PSMA5 | 5686 | 201274_at | 0.2949 | 0.0406 | |
| GSE45670 | PSMA5 | 5686 | 201274_at | 0.3702 | 0.0067 | |
| GSE53622 | PSMA5 | 5686 | 18919 | 0.2277 | 0.0008 | |
| GSE53624 | PSMA5 | 5686 | 18919 | 0.3460 | 0.0000 | |
| GSE63941 | PSMA5 | 5686 | 201274_at | 0.4707 | 0.2054 | |
| GSE77861 | PSMA5 | 5686 | 201274_at | 0.2054 | 0.4878 | |
| GSE97050 | PSMA5 | 5686 | A_23_P86216 | 0.3407 | 0.3008 | |
| SRP007169 | PSMA5 | 5686 | RNAseq | -0.2235 | 0.5333 | |
| SRP008496 | PSMA5 | 5686 | RNAseq | -0.6510 | 0.0028 | |
| SRP064894 | PSMA5 | 5686 | RNAseq | 0.2226 | 0.2369 | |
| SRP133303 | PSMA5 | 5686 | RNAseq | 0.4156 | 0.0323 | |
| SRP159526 | PSMA5 | 5686 | RNAseq | -0.2153 | 0.4085 | |
| SRP193095 | PSMA5 | 5686 | RNAseq | -0.2036 | 0.1137 | |
| SRP219564 | PSMA5 | 5686 | RNAseq | 0.3521 | 0.4700 | |
| TCGA | PSMA5 | 5686 | RNAseq | 0.1723 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMA5 | 5686 | 0 | 12 | 18 | |
| GSE20123 | PSMA5 | 5686 | 0 | 11 | 19 | |
| GSE43470 | PSMA5 | 5686 | 0 | 8 | 35 | |
| GSE46452 | PSMA5 | 5686 | 2 | 1 | 56 | |
| GSE47630 | PSMA5 | 5686 | 9 | 6 | 25 | |
| GSE54993 | PSMA5 | 5686 | 0 | 1 | 69 | |
| GSE54994 | PSMA5 | 5686 | 7 | 4 | 42 | |
| GSE60625 | PSMA5 | 5686 | 0 | 0 | 11 | |
| GSE74703 | PSMA5 | 5686 | 0 | 6 | 30 | |
| GSE74704 | PSMA5 | 5686 | 0 | 7 | 13 | |
| TCGA | PSMA5 | 5686 | 8 | 26 | 62 |
Total number of gains: 26; Total number of losses: 82; Total Number of normals: 380.
Somatic mutations of PSMA5:
Generating mutation plots.
Highly correlated genes for PSMA5:
Showing top 20/951 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMA5 | MAP2K1 | 0.776481 | 3 | 0 | 3 |
| PSMA5 | ASB7 | 0.773878 | 3 | 0 | 3 |
| PSMA5 | CD163L1 | 0.772401 | 3 | 0 | 3 |
| PSMA5 | VAMP3 | 0.768073 | 3 | 0 | 3 |
| PSMA5 | CDC26 | 0.759688 | 3 | 0 | 3 |
| PSMA5 | IL10RB | 0.749422 | 3 | 0 | 3 |
| PSMA5 | CALCRL | 0.747864 | 3 | 0 | 3 |
| PSMA5 | LRRC28 | 0.744009 | 3 | 0 | 3 |
| PSMA5 | TMEM54 | 0.736288 | 3 | 0 | 3 |
| PSMA5 | USP3 | 0.733746 | 3 | 0 | 3 |
| PSMA5 | REST | 0.7308 | 3 | 0 | 3 |
| PSMA5 | ACAP2 | 0.730582 | 3 | 0 | 3 |
| PSMA5 | ATP11B | 0.726815 | 3 | 0 | 3 |
| PSMA5 | GAPT | 0.725226 | 3 | 0 | 3 |
| PSMA5 | APH1B | 0.72371 | 3 | 0 | 3 |
| PSMA5 | MRPS35 | 0.716972 | 6 | 0 | 5 |
| PSMA5 | ZNF18 | 0.71494 | 3 | 0 | 3 |
| PSMA5 | DYRK2 | 0.714358 | 3 | 0 | 3 |
| PSMA5 | NUB1 | 0.711816 | 3 | 0 | 3 |
| PSMA5 | EFCAB7 | 0.705758 | 3 | 0 | 3 |
For details and further investigation, click here
