| Full name: UV radiation resistance associated | Alias Symbol: VPS38 | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 7405 | HGNC ID: HGNC:12640 | Ensembl Gene: ENSG00000198382 | OMIM ID: 602493 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UVRAG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UVRAG | 7405 | 203241_at | 0.1770 | 0.7799 | |
| GSE20347 | UVRAG | 7405 | 203241_at | 0.5574 | 0.0204 | |
| GSE23400 | UVRAG | 7405 | 203241_at | 0.5215 | 0.0000 | |
| GSE26886 | UVRAG | 7405 | 203241_at | 0.6590 | 0.0088 | |
| GSE29001 | UVRAG | 7405 | 203241_at | 0.3609 | 0.1017 | |
| GSE38129 | UVRAG | 7405 | 203241_at | 0.4233 | 0.0210 | |
| GSE45670 | UVRAG | 7405 | 203241_at | 0.0305 | 0.9254 | |
| GSE53622 | UVRAG | 7405 | 71354 | -0.0086 | 0.9182 | |
| GSE53624 | UVRAG | 7405 | 71354 | -1.0089 | 0.0000 | |
| GSE63941 | UVRAG | 7405 | 203241_at | 0.6119 | 0.3779 | |
| GSE77861 | UVRAG | 7405 | 203241_at | 0.4625 | 0.1324 | |
| GSE97050 | UVRAG | 7405 | A_33_P3260722 | -0.1720 | 0.5287 | |
| SRP007169 | UVRAG | 7405 | RNAseq | 0.9825 | 0.0285 | |
| SRP008496 | UVRAG | 7405 | RNAseq | 1.2709 | 0.0002 | |
| SRP064894 | UVRAG | 7405 | RNAseq | 0.4670 | 0.0549 | |
| SRP133303 | UVRAG | 7405 | RNAseq | -0.0669 | 0.5685 | |
| SRP159526 | UVRAG | 7405 | RNAseq | 0.3388 | 0.0841 | |
| SRP193095 | UVRAG | 7405 | RNAseq | 0.2929 | 0.1313 | |
| SRP219564 | UVRAG | 7405 | RNAseq | 0.2430 | 0.5899 | |
| TCGA | UVRAG | 7405 | RNAseq | -0.0251 | 0.6749 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by UVRAG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UVRAG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UVRAG | 7405 | 6 | 8 | 16 | |
| GSE20123 | UVRAG | 7405 | 6 | 7 | 17 | |
| GSE43470 | UVRAG | 7405 | 3 | 4 | 36 | |
| GSE46452 | UVRAG | 7405 | 7 | 22 | 30 | |
| GSE47630 | UVRAG | 7405 | 7 | 14 | 19 | |
| GSE54993 | UVRAG | 7405 | 8 | 2 | 60 | |
| GSE54994 | UVRAG | 7405 | 7 | 17 | 29 | |
| GSE60625 | UVRAG | 7405 | 4 | 3 | 4 | |
| GSE74703 | UVRAG | 7405 | 2 | 3 | 31 | |
| GSE74704 | UVRAG | 7405 | 4 | 3 | 13 | |
| TCGA | UVRAG | 7405 | 20 | 32 | 44 |
Total number of gains: 74; Total number of losses: 115; Total Number of normals: 299.
Somatic mutations of UVRAG:
Generating mutation plots.
Highly correlated genes for UVRAG:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UVRAG | CCDC51 | 0.764511 | 4 | 0 | 3 |
| UVRAG | DPY19L2 | 0.7624 | 3 | 0 | 3 |
| UVRAG | ZNF18 | 0.721816 | 3 | 0 | 3 |
| UVRAG | C20orf194 | 0.713513 | 3 | 0 | 3 |
| UVRAG | CRTC3 | 0.699292 | 4 | 0 | 4 |
| UVRAG | HERC2 | 0.685862 | 4 | 0 | 4 |
| UVRAG | TMTC1 | 0.684275 | 4 | 0 | 4 |
| UVRAG | PPP1R21 | 0.671835 | 3 | 0 | 3 |
| UVRAG | KIAA1257 | 0.669495 | 3 | 0 | 3 |
| UVRAG | MLH3 | 0.652017 | 3 | 0 | 3 |
| UVRAG | ZFHX3 | 0.650805 | 4 | 0 | 4 |
| UVRAG | GOLGA3 | 0.650774 | 3 | 0 | 3 |
| UVRAG | NUDCD3 | 0.65008 | 3 | 0 | 3 |
| UVRAG | RBM17 | 0.637529 | 3 | 0 | 3 |
| UVRAG | RASSF8 | 0.631973 | 4 | 0 | 3 |
| UVRAG | SGTB | 0.627901 | 3 | 0 | 3 |
| UVRAG | AP3B2 | 0.625613 | 3 | 0 | 3 |
| UVRAG | RAMP1 | 0.625322 | 4 | 0 | 3 |
| UVRAG | TMTC4 | 0.624039 | 4 | 0 | 3 |
| UVRAG | TMED8 | 0.619634 | 3 | 0 | 3 |
For details and further investigation, click here
