| Full name: FAM20B glycosaminoglycan xylosylkinase | Alias Symbol: KIAA0475|GXK1 | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 9917 | HGNC ID: HGNC:23017 | Ensembl Gene: ENSG00000116199 | OMIM ID: 611063 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM20B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM20B | 9917 | 202916_s_at | 0.2957 | 0.6789 | |
| GSE20347 | FAM20B | 9917 | 202915_s_at | 0.2784 | 0.1257 | |
| GSE23400 | FAM20B | 9917 | 202916_s_at | 0.1977 | 0.0442 | |
| GSE26886 | FAM20B | 9917 | 202916_s_at | 0.2690 | 0.4173 | |
| GSE29001 | FAM20B | 9917 | 202916_s_at | 0.6361 | 0.0904 | |
| GSE38129 | FAM20B | 9917 | 202916_s_at | 0.3726 | 0.0109 | |
| GSE45670 | FAM20B | 9917 | 202916_s_at | -0.1152 | 0.5987 | |
| GSE53622 | FAM20B | 9917 | 62681 | -0.2407 | 0.0067 | |
| GSE53624 | FAM20B | 9917 | 62681 | 0.2975 | 0.0000 | |
| GSE63941 | FAM20B | 9917 | 202915_s_at | 0.2306 | 0.5101 | |
| GSE77861 | FAM20B | 9917 | 202915_s_at | 1.0525 | 0.0040 | |
| GSE97050 | FAM20B | 9917 | A_24_P148043 | -0.5752 | 0.2371 | |
| SRP007169 | FAM20B | 9917 | RNAseq | 0.2587 | 0.5199 | |
| SRP008496 | FAM20B | 9917 | RNAseq | 0.7579 | 0.0098 | |
| SRP064894 | FAM20B | 9917 | RNAseq | 0.1653 | 0.1948 | |
| SRP133303 | FAM20B | 9917 | RNAseq | 0.4182 | 0.0157 | |
| SRP159526 | FAM20B | 9917 | RNAseq | 0.9333 | 0.0100 | |
| SRP193095 | FAM20B | 9917 | RNAseq | 0.3853 | 0.0009 | |
| SRP219564 | FAM20B | 9917 | RNAseq | -0.0064 | 0.9879 | |
| TCGA | FAM20B | 9917 | RNAseq | -0.0284 | 0.6198 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FAM20B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM20B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM20B | 9917 | 12 | 0 | 18 | |
| GSE20123 | FAM20B | 9917 | 12 | 0 | 18 | |
| GSE43470 | FAM20B | 9917 | 9 | 1 | 33 | |
| GSE46452 | FAM20B | 9917 | 3 | 1 | 55 | |
| GSE47630 | FAM20B | 9917 | 14 | 0 | 26 | |
| GSE54993 | FAM20B | 9917 | 0 | 6 | 64 | |
| GSE54994 | FAM20B | 9917 | 15 | 0 | 38 | |
| GSE60625 | FAM20B | 9917 | 0 | 0 | 11 | |
| GSE74703 | FAM20B | 9917 | 8 | 1 | 27 | |
| GSE74704 | FAM20B | 9917 | 5 | 0 | 15 | |
| TCGA | FAM20B | 9917 | 40 | 4 | 52 |
Total number of gains: 118; Total number of losses: 13; Total Number of normals: 357.
Somatic mutations of FAM20B:
Generating mutation plots.
Highly correlated genes for FAM20B:
Showing top 20/929 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM20B | SLC39A13 | 0.799613 | 3 | 0 | 3 |
| FAM20B | PRICKLE1 | 0.782184 | 3 | 0 | 3 |
| FAM20B | BRD2 | 0.77409 | 3 | 0 | 3 |
| FAM20B | PRRC2C | 0.764606 | 3 | 0 | 3 |
| FAM20B | GTPBP6 | 0.764436 | 3 | 0 | 3 |
| FAM20B | FAN1 | 0.760705 | 3 | 0 | 3 |
| FAM20B | TFDP2 | 0.741065 | 3 | 0 | 3 |
| FAM20B | ZNF689 | 0.739271 | 3 | 0 | 3 |
| FAM20B | ZNF18 | 0.732773 | 3 | 0 | 3 |
| FAM20B | KBTBD7 | 0.731783 | 4 | 0 | 4 |
| FAM20B | ZNF791 | 0.725815 | 3 | 0 | 3 |
| FAM20B | ZNF579 | 0.72383 | 3 | 0 | 3 |
| FAM20B | THOC1 | 0.719753 | 3 | 0 | 3 |
| FAM20B | TMEM181 | 0.715418 | 4 | 0 | 4 |
| FAM20B | EIF5B | 0.713861 | 3 | 0 | 3 |
| FAM20B | CRKL | 0.707933 | 4 | 0 | 3 |
| FAM20B | VMA21 | 0.705109 | 3 | 0 | 3 |
| FAM20B | VRK3 | 0.700225 | 3 | 0 | 3 |
| FAM20B | NXF1 | 0.696919 | 4 | 0 | 4 |
| FAM20B | TNRC18 | 0.695003 | 4 | 0 | 3 |
For details and further investigation, click here
