| Full name: host cell factor C1 | Alias Symbol: HCF-1|HCF1|CFF|VCAF|MGC70925|PPP1R89 | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 3054 | HGNC ID: HGNC:4839 | Ensembl Gene: ENSG00000172534 | OMIM ID: 300019 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
HCFC1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05168 | Herpes simplex infection |
Expression of HCFC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HCFC1 | 3054 | 202474_s_at | 0.2739 | 0.3864 | |
| GSE20347 | HCFC1 | 3054 | 202474_s_at | 0.2645 | 0.0003 | |
| GSE23400 | HCFC1 | 3054 | 202474_s_at | 0.2090 | 0.0000 | |
| GSE26886 | HCFC1 | 3054 | 202474_s_at | 0.4543 | 0.0009 | |
| GSE29001 | HCFC1 | 3054 | 202474_s_at | 0.1922 | 0.2168 | |
| GSE38129 | HCFC1 | 3054 | 202474_s_at | 0.1915 | 0.0643 | |
| GSE45670 | HCFC1 | 3054 | 202474_s_at | 0.1773 | 0.0075 | |
| GSE53622 | HCFC1 | 3054 | 80018 | 0.3055 | 0.0000 | |
| GSE53624 | HCFC1 | 3054 | 80018 | 0.4388 | 0.0000 | |
| GSE63941 | HCFC1 | 3054 | 202474_s_at | 0.5479 | 0.0122 | |
| GSE77861 | HCFC1 | 3054 | 202474_s_at | 0.2227 | 0.0743 | |
| GSE97050 | HCFC1 | 3054 | A_23_P125771 | 0.1815 | 0.4426 | |
| SRP007169 | HCFC1 | 3054 | RNAseq | 1.6694 | 0.0003 | |
| SRP008496 | HCFC1 | 3054 | RNAseq | 1.4758 | 0.0000 | |
| SRP064894 | HCFC1 | 3054 | RNAseq | 0.5865 | 0.0004 | |
| SRP133303 | HCFC1 | 3054 | RNAseq | 0.5038 | 0.0040 | |
| SRP159526 | HCFC1 | 3054 | RNAseq | 0.4895 | 0.0214 | |
| SRP193095 | HCFC1 | 3054 | RNAseq | 0.4997 | 0.0000 | |
| SRP219564 | HCFC1 | 3054 | RNAseq | 0.1926 | 0.4035 | |
| TCGA | HCFC1 | 3054 | RNAseq | 0.0262 | 0.5184 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by HCFC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HCFC1:
No record found for this gene.
Somatic mutations of HCFC1:
Generating mutation plots.
Highly correlated genes for HCFC1:
Showing top 20/1177 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HCFC1 | PACS1 | 0.765951 | 3 | 0 | 3 |
| HCFC1 | SLC39A3 | 0.761057 | 4 | 0 | 4 |
| HCFC1 | NOC3L | 0.74954 | 3 | 0 | 3 |
| HCFC1 | FHL3 | 0.746602 | 4 | 0 | 4 |
| HCFC1 | LNP1 | 0.742459 | 3 | 0 | 3 |
| HCFC1 | ZNF18 | 0.732831 | 3 | 0 | 3 |
| HCFC1 | KCNMB4 | 0.731033 | 3 | 0 | 3 |
| HCFC1 | TTLL1 | 0.729393 | 3 | 0 | 3 |
| HCFC1 | ZSCAN21 | 0.721894 | 3 | 0 | 3 |
| HCFC1 | SREBF1 | 0.713072 | 3 | 0 | 3 |
| HCFC1 | RNASEH2C | 0.703394 | 4 | 0 | 4 |
| HCFC1 | DEDD | 0.702504 | 4 | 0 | 3 |
| HCFC1 | TRAF7 | 0.701356 | 4 | 0 | 4 |
| HCFC1 | IDS | 0.701042 | 3 | 0 | 3 |
| HCFC1 | MAP3K7 | 0.7007 | 3 | 0 | 3 |
| HCFC1 | GNA11 | 0.699398 | 5 | 0 | 4 |
| HCFC1 | GTPBP1 | 0.698487 | 3 | 0 | 3 |
| HCFC1 | DHDH | 0.698183 | 3 | 0 | 3 |
| HCFC1 | SSBP4 | 0.697864 | 5 | 0 | 4 |
| HCFC1 | TTYH2 | 0.693894 | 3 | 0 | 3 |
For details and further investigation, click here
