| Full name: transmembrane protein 185B | Alias Symbol: FLJ20979 | ||
| Type: protein-coding gene | Cytoband: 2q14.2 | ||
| Entrez ID: 79134 | HGNC ID: HGNC:18896 | Ensembl Gene: ENSG00000226479 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM185B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM185B | 79134 | 219253_at | 1.1617 | 0.0359 | |
| GSE20347 | TMEM185B | 79134 | 219253_at | 1.0846 | 0.0000 | |
| GSE23400 | TMEM185B | 79134 | 219253_at | 1.2044 | 0.0000 | |
| GSE26886 | TMEM185B | 79134 | 219253_at | 0.5332 | 0.0735 | |
| GSE29001 | TMEM185B | 79134 | 219253_at | 1.0574 | 0.0001 | |
| GSE38129 | TMEM185B | 79134 | 219253_at | 1.2162 | 0.0000 | |
| GSE45670 | TMEM185B | 79134 | 219253_at | 1.1363 | 0.0000 | |
| GSE53622 | TMEM185B | 79134 | 1343 | 0.9225 | 0.0000 | |
| GSE53624 | TMEM185B | 79134 | 1343 | 1.2095 | 0.0000 | |
| GSE63941 | TMEM185B | 79134 | 219253_at | 1.0099 | 0.0137 | |
| GSE77861 | TMEM185B | 79134 | 219253_at | 1.0950 | 0.0117 | |
| GSE97050 | TMEM185B | 79134 | A_23_P119789 | 0.7358 | 0.1313 | |
| SRP007169 | TMEM185B | 79134 | RNAseq | 1.8657 | 0.0001 | |
| SRP008496 | TMEM185B | 79134 | RNAseq | 2.2662 | 0.0000 | |
| SRP064894 | TMEM185B | 79134 | RNAseq | 0.8560 | 0.0000 | |
| SRP133303 | TMEM185B | 79134 | RNAseq | 0.6778 | 0.0001 | |
| SRP159526 | TMEM185B | 79134 | RNAseq | 1.1638 | 0.0016 | |
| SRP193095 | TMEM185B | 79134 | RNAseq | 0.8218 | 0.0000 | |
| SRP219564 | TMEM185B | 79134 | RNAseq | 0.1851 | 0.4724 | |
| TCGA | TMEM185B | 79134 | RNAseq | 0.2449 | 0.0001 |
Upregulated datasets: 12; Downregulated datasets: 0.
Survival by TMEM185B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM185B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM185B | 79134 | 6 | 2 | 22 | |
| GSE20123 | TMEM185B | 79134 | 6 | 2 | 22 | |
| GSE43470 | TMEM185B | 79134 | 3 | 1 | 39 | |
| GSE46452 | TMEM185B | 79134 | 2 | 3 | 54 | |
| GSE47630 | TMEM185B | 79134 | 6 | 0 | 34 | |
| GSE54993 | TMEM185B | 79134 | 0 | 6 | 64 | |
| GSE54994 | TMEM185B | 79134 | 12 | 0 | 41 | |
| GSE60625 | TMEM185B | 79134 | 0 | 3 | 8 | |
| GSE74703 | TMEM185B | 79134 | 3 | 1 | 32 | |
| GSE74704 | TMEM185B | 79134 | 3 | 1 | 16 | |
| TCGA | TMEM185B | 79134 | 32 | 6 | 58 |
Total number of gains: 73; Total number of losses: 25; Total Number of normals: 390.
Somatic mutations of TMEM185B:
Generating mutation plots.
Highly correlated genes for TMEM185B:
Showing top 20/1953 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM185B | PPP1R16A | 0.81202 | 3 | 0 | 3 |
| TMEM185B | TNFRSF1A | 0.79398 | 3 | 0 | 3 |
| TMEM185B | LRRC58 | 0.785861 | 5 | 0 | 5 |
| TMEM185B | GMPS | 0.769371 | 11 | 0 | 11 |
| TMEM185B | TMEM138 | 0.759837 | 7 | 0 | 7 |
| TMEM185B | HAT1 | 0.754856 | 12 | 0 | 12 |
| TMEM185B | LRP12 | 0.753944 | 11 | 0 | 11 |
| TMEM185B | SLC36A4 | 0.753189 | 3 | 0 | 3 |
| TMEM185B | HSPD1 | 0.746387 | 11 | 0 | 11 |
| TMEM185B | ZNF114 | 0.746342 | 3 | 0 | 3 |
| TMEM185B | ATP6V1C1 | 0.743708 | 12 | 0 | 12 |
| TMEM185B | FBXO45 | 0.743175 | 3 | 0 | 3 |
| TMEM185B | MTBP | 0.742515 | 6 | 0 | 6 |
| TMEM185B | WDR54 | 0.739422 | 5 | 0 | 5 |
| TMEM185B | PSME4 | 0.73593 | 11 | 0 | 11 |
| TMEM185B | ZNF18 | 0.735914 | 4 | 0 | 4 |
| TMEM185B | HMGB3 | 0.735689 | 11 | 0 | 11 |
| TMEM185B | FAM89A | 0.734772 | 3 | 0 | 3 |
| TMEM185B | SLC2A9 | 0.733072 | 3 | 0 | 3 |
| TMEM185B | U2SURP | 0.730833 | 9 | 0 | 8 |
For details and further investigation, click here
