TOR1A

 

Full name: torsin family 1 member A Alias Symbol: DQ2
Type: protein-coding gene Cytoband: 9q34.11
Entrez ID: 1861 HGNC ID: HGNC:3098 Ensembl Gene: ENSG00000136827 OMIM ID: 605204
Drug and gene relationship at DGIdb

 

Expression of TOR1A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TOR1A 1861 202348_s_at 0.1855 0.3963
GSE20347 TOR1A 1861 202349_at 0.1420 0.3968
GSE23400 TOR1A 1861 202348_s_at 0.4063 0.0000
GSE26886 TOR1A 1861 202349_at 0.3932 0.0155
GSE29001 TOR1A 1861 202349_at 0.5043 0.0089
GSE38129 TOR1A 1861 202348_s_at 0.3347 0.0155
GSE45670 TOR1A 1861 202348_s_at 0.2922 0.0376
GSE63941 TOR1A 1861 202348_s_at -0.1826 0.6267
GSE77861 TOR1A 1861 202348_s_at 0.4902 0.0017
GSE97050 TOR1A 1861 A_33_P3313889 0.1098 0.6253
SRP007169 TOR1A 1861 RNAseq 0.7867 0.0510
SRP008496 TOR1A 1861 RNAseq 0.9066 0.0004
SRP064894 TOR1A 1861 RNAseq 0.8872 0.0000
SRP133303 TOR1A 1861 RNAseq 0.5949 0.0002
SRP159526 TOR1A 1861 RNAseq 0.7121 0.0000
SRP193095 TOR1A 1861 RNAseq 0.3634 0.0031
SRP219564 TOR1A 1861 RNAseq 0.1928 0.4531
TCGA TOR1A 1861 RNAseq 0.1037 0.0514

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TOR1A expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of TOR1A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TOR1A 1861 6 9 15
GSE20123 TOR1A 1861 6 9 15
GSE43470 TOR1A 1861 5 7 31
GSE46452 TOR1A 1861 6 13 40
GSE47630 TOR1A 1861 3 16 21
GSE54993 TOR1A 1861 3 3 64
GSE54994 TOR1A 1861 12 9 32
GSE60625 TOR1A 1861 0 0 11
GSE74703 TOR1A 1861 5 5 26
GSE74704 TOR1A 1861 3 7 10
TCGA TOR1A 1861 27 26 43

Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.  


 

Somatic mutations of TOR1A:

 

Generating mutation plots.

 

Highly correlated genes for TOR1A:

 

Showing top 20/1328 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TOR1ASAFB20.841203303
TOR1ASLC25A360.827242303
TOR1AWDR810.80837303
TOR1AALG20.807368404
TOR1ASLC37A30.802874303
TOR1ADUS3L0.797542303
TOR1AALKBH60.776019303
TOR1ANF20.749208303
TOR1ADNAH140.749166303
TOR1ASP40.738863303
TOR1ACD99L20.738347303
TOR1ALMLN0.735681303
TOR1AHEATR60.735542404
TOR1ATMEM1380.735264404
TOR1ACOQ30.734412303
TOR1AIRF2BPL0.734135303
TOR1ATRIB10.732952303
TOR1AAAK10.732054303
TOR1AINTS90.729867303
TOR1ANOM10.72956303

For details and further investigation, click here