ZNF84

 

Full name: zinc finger protein 84 Alias Symbol: HPF2
Type: protein-coding gene Cytoband: 12q24.33
Entrez ID: 7637 HGNC ID: HGNC:13159 Ensembl Gene: ENSG00000198040 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZNF84:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF84 7637 204453_at 0.1138 0.9107
GSE20347 ZNF84 7637 204453_at 0.6323 0.0007
GSE23400 ZNF84 7637 204453_at 0.2482 0.0000
GSE26886 ZNF84 7637 228630_at 0.0384 0.9400
GSE29001 ZNF84 7637 204453_at 0.3142 0.4470
GSE38129 ZNF84 7637 204453_at 0.4306 0.0011
GSE45670 ZNF84 7637 204453_at 0.1882 0.1830
GSE53622 ZNF84 7637 13693 0.1153 0.2127
GSE53624 ZNF84 7637 13693 0.3654 0.0000
GSE63941 ZNF84 7637 204453_at -1.0630 0.0388
GSE77861 ZNF84 7637 204453_at 0.3829 0.0830
GSE97050 ZNF84 7637 A_23_P105276 -0.2883 0.1852
SRP007169 ZNF84 7637 RNAseq 1.2705 0.0038
SRP008496 ZNF84 7637 RNAseq 1.3859 0.0000
SRP064894 ZNF84 7637 RNAseq 0.1712 0.3888
SRP133303 ZNF84 7637 RNAseq -0.2495 0.3258
SRP159526 ZNF84 7637 RNAseq 0.5071 0.2566
SRP193095 ZNF84 7637 RNAseq 0.2166 0.0822
SRP219564 ZNF84 7637 RNAseq -0.4382 0.1294
TCGA ZNF84 7637 RNAseq -0.1722 0.0312

Upregulated datasets: 2; Downregulated datasets: 1.  


 

Survival by ZNF84 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF84:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF84 7637 4 5 21
GSE20123 ZNF84 7637 4 5 21
GSE43470 ZNF84 7637 3 3 37
GSE46452 ZNF84 7637 8 3 48
GSE47630 ZNF84 7637 9 3 28
GSE54993 ZNF84 7637 0 6 64
GSE54994 ZNF84 7637 4 8 41
GSE60625 ZNF84 7637 1 0 10
GSE74703 ZNF84 7637 2 3 31
GSE74704 ZNF84 7637 2 3 15
TCGA ZNF84 7637 21 15 60

Total number of gains: 58; Total number of losses: 54; Total Number of normals: 376.  


 

Somatic mutations of ZNF84:

 

Generating mutation plots.

 

Highly correlated genes for ZNF84:

 

Showing top 20/82 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF84ZNF3290.727876404
ZNF84ZNF5010.688136303
ZNF84EFR3A0.641391404
ZNF84CCDC1220.63227403
ZNF84BRAF0.627295303
ZNF84VAMP40.618392504
ZNF84ZNF260.611091107
ZNF84CCDC890.608409303
ZNF84BPTF0.607125403
ZNF84ZNF6050.606393806
ZNF84AUTS20.602914604
ZNF84PRPF180.596562303
ZNF84FAM50B0.593454403
ZNF84BRD10.593285504
ZNF84ZNF7770.58543403
ZNF84HIVEP20.581704303
ZNF84UVRAG0.578495605
ZNF84TMEM2600.575568705
ZNF84ZNF2320.5753531108
ZNF84MAGEA110.573562403

For details and further investigation, click here