| Full name: vesicle associated membrane protein 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q24.3 | ||
| Entrez ID: 8674 | HGNC ID: HGNC:12645 | Ensembl Gene: ENSG00000117533 | OMIM ID: 606909 |
| Drug and gene relationship at DGIdb | |||
Expression of VAMP4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VAMP4 | 8674 | 213480_at | -0.3218 | 0.3066 | |
| GSE20347 | VAMP4 | 8674 | 213480_at | -0.1417 | 0.3546 | |
| GSE23400 | VAMP4 | 8674 | 213480_at | -0.0101 | 0.8920 | |
| GSE26886 | VAMP4 | 8674 | 213480_at | 0.4952 | 0.0652 | |
| GSE29001 | VAMP4 | 8674 | 213480_at | 0.0750 | 0.8381 | |
| GSE38129 | VAMP4 | 8674 | 213480_at | -0.2757 | 0.0344 | |
| GSE45670 | VAMP4 | 8674 | 213480_at | -0.6015 | 0.0000 | |
| GSE53622 | VAMP4 | 8674 | 83770 | -0.2734 | 0.0003 | |
| GSE53624 | VAMP4 | 8674 | 59270 | -0.0205 | 0.8113 | |
| GSE63941 | VAMP4 | 8674 | 213480_at | -1.6364 | 0.0023 | |
| GSE77861 | VAMP4 | 8674 | 213480_at | 0.4726 | 0.0305 | |
| GSE97050 | VAMP4 | 8674 | A_24_P942030 | -0.2104 | 0.4510 | |
| SRP007169 | VAMP4 | 8674 | RNAseq | -0.7196 | 0.0391 | |
| SRP008496 | VAMP4 | 8674 | RNAseq | 0.2253 | 0.5142 | |
| SRP064894 | VAMP4 | 8674 | RNAseq | 0.0136 | 0.9413 | |
| SRP133303 | VAMP4 | 8674 | RNAseq | 0.1955 | 0.2026 | |
| SRP159526 | VAMP4 | 8674 | RNAseq | -0.2315 | 0.3829 | |
| SRP193095 | VAMP4 | 8674 | RNAseq | 0.0922 | 0.3422 | |
| SRP219564 | VAMP4 | 8674 | RNAseq | 0.0243 | 0.8962 | |
| TCGA | VAMP4 | 8674 | RNAseq | -0.0994 | 0.0682 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VAMP4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAMP4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAMP4 | 8674 | 12 | 1 | 17 | |
| GSE20123 | VAMP4 | 8674 | 12 | 1 | 17 | |
| GSE43470 | VAMP4 | 8674 | 7 | 2 | 34 | |
| GSE46452 | VAMP4 | 8674 | 3 | 1 | 55 | |
| GSE47630 | VAMP4 | 8674 | 14 | 0 | 26 | |
| GSE54993 | VAMP4 | 8674 | 0 | 6 | 64 | |
| GSE54994 | VAMP4 | 8674 | 16 | 0 | 37 | |
| GSE60625 | VAMP4 | 8674 | 0 | 0 | 11 | |
| GSE74703 | VAMP4 | 8674 | 7 | 2 | 27 | |
| GSE74704 | VAMP4 | 8674 | 6 | 0 | 14 | |
| TCGA | VAMP4 | 8674 | 42 | 3 | 51 |
Total number of gains: 119; Total number of losses: 16; Total Number of normals: 353.
Somatic mutations of VAMP4:
Generating mutation plots.
Highly correlated genes for VAMP4:
Showing top 20/213 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAMP4 | INSC | 0.790398 | 3 | 0 | 3 |
| VAMP4 | GPR146 | 0.743478 | 3 | 0 | 3 |
| VAMP4 | MGARP | 0.717588 | 3 | 0 | 3 |
| VAMP4 | GATA2 | 0.715941 | 3 | 0 | 3 |
| VAMP4 | PPP1R14A | 0.713589 | 3 | 0 | 3 |
| VAMP4 | RNF180 | 0.711488 | 3 | 0 | 3 |
| VAMP4 | UCK1 | 0.70955 | 3 | 0 | 3 |
| VAMP4 | BRD1 | 0.696416 | 3 | 0 | 3 |
| VAMP4 | RWDD3 | 0.691045 | 3 | 0 | 3 |
| VAMP4 | FGF14 | 0.688449 | 4 | 0 | 3 |
| VAMP4 | BCL2L13 | 0.685072 | 4 | 0 | 3 |
| VAMP4 | TBX5-AS1 | 0.682949 | 3 | 0 | 3 |
| VAMP4 | NPPC | 0.680705 | 3 | 0 | 3 |
| VAMP4 | DVL2 | 0.680376 | 3 | 0 | 3 |
| VAMP4 | MAGI2-AS3 | 0.67586 | 4 | 0 | 4 |
| VAMP4 | SMIM10 | 0.671402 | 5 | 0 | 4 |
| VAMP4 | NEXN | 0.669994 | 4 | 0 | 4 |
| VAMP4 | CNTN3 | 0.669113 | 4 | 0 | 3 |
| VAMP4 | C14orf28 | 0.667604 | 3 | 0 | 3 |
| VAMP4 | CCDC8 | 0.66425 | 3 | 0 | 3 |
For details and further investigation, click here
