| Full name: EFR3 homolog A | Alias Symbol: KIAA0143 | ||
| Type: protein-coding gene | Cytoband: 8q24.22 | ||
| Entrez ID: 23167 | HGNC ID: HGNC:28970 | Ensembl Gene: ENSG00000132294 | OMIM ID: 611798 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EFR3A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFR3A | 23167 | 212149_at | 0.4748 | 0.2248 | |
| GSE20347 | EFR3A | 23167 | 212149_at | 0.2250 | 0.0475 | |
| GSE23400 | EFR3A | 23167 | 212149_at | 0.4136 | 0.0000 | |
| GSE26886 | EFR3A | 23167 | 212149_at | -0.0485 | 0.8573 | |
| GSE29001 | EFR3A | 23167 | 212149_at | 0.3084 | 0.0194 | |
| GSE38129 | EFR3A | 23167 | 212149_at | 0.1504 | 0.1700 | |
| GSE45670 | EFR3A | 23167 | 212149_at | 0.4481 | 0.0039 | |
| GSE63941 | EFR3A | 23167 | 212149_at | -0.1594 | 0.7156 | |
| GSE77861 | EFR3A | 23167 | 212149_at | 0.0516 | 0.6971 | |
| GSE97050 | EFR3A | 23167 | A_23_P71513 | -0.1236 | 0.7743 | |
| SRP007169 | EFR3A | 23167 | RNAseq | 0.7077 | 0.0630 | |
| SRP008496 | EFR3A | 23167 | RNAseq | 0.8058 | 0.0002 | |
| SRP064894 | EFR3A | 23167 | RNAseq | 0.4890 | 0.0455 | |
| SRP133303 | EFR3A | 23167 | RNAseq | 0.6454 | 0.0000 | |
| SRP159526 | EFR3A | 23167 | RNAseq | -0.0160 | 0.9607 | |
| SRP193095 | EFR3A | 23167 | RNAseq | 0.2592 | 0.0139 | |
| SRP219564 | EFR3A | 23167 | RNAseq | -0.0303 | 0.8958 | |
| TCGA | EFR3A | 23167 | RNAseq | 0.0259 | 0.5976 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EFR3A expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EFR3A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFR3A | 23167 | 18 | 0 | 12 | |
| GSE20123 | EFR3A | 23167 | 18 | 0 | 12 | |
| GSE43470 | EFR3A | 23167 | 23 | 0 | 20 | |
| GSE46452 | EFR3A | 23167 | 27 | 0 | 32 | |
| GSE47630 | EFR3A | 23167 | 24 | 0 | 16 | |
| GSE54993 | EFR3A | 23167 | 0 | 24 | 46 | |
| GSE54994 | EFR3A | 23167 | 39 | 1 | 13 | |
| GSE60625 | EFR3A | 23167 | 0 | 7 | 4 | |
| GSE74703 | EFR3A | 23167 | 20 | 0 | 16 | |
| GSE74704 | EFR3A | 23167 | 12 | 0 | 8 | |
| TCGA | EFR3A | 23167 | 67 | 2 | 27 |
Total number of gains: 248; Total number of losses: 34; Total Number of normals: 206.
Somatic mutations of EFR3A:
Generating mutation plots.
Highly correlated genes for EFR3A:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFR3A | ZNF133 | 0.77214 | 3 | 0 | 3 |
| EFR3A | IL12RB2 | 0.702228 | 3 | 0 | 3 |
| EFR3A | CCDC122 | 0.680414 | 3 | 0 | 3 |
| EFR3A | TMEM9 | 0.673435 | 3 | 0 | 3 |
| EFR3A | HSD11B1L | 0.669943 | 3 | 0 | 3 |
| EFR3A | ZNF84 | 0.641391 | 4 | 0 | 4 |
| EFR3A | GPR180 | 0.632888 | 4 | 0 | 3 |
| EFR3A | MED20 | 0.628192 | 4 | 0 | 3 |
| EFR3A | PLEKHA1 | 0.62806 | 3 | 0 | 3 |
| EFR3A | GIT2 | 0.627951 | 3 | 0 | 3 |
| EFR3A | FBXL2 | 0.618481 | 4 | 0 | 3 |
| EFR3A | MRPS17 | 0.618165 | 4 | 0 | 3 |
| EFR3A | MTERF3 | 0.614285 | 7 | 0 | 6 |
| EFR3A | XCL1 | 0.610161 | 4 | 0 | 3 |
| EFR3A | TMEM182 | 0.607643 | 3 | 0 | 3 |
| EFR3A | CDK12 | 0.605969 | 3 | 0 | 3 |
| EFR3A | SHARPIN | 0.600956 | 5 | 0 | 3 |
| EFR3A | YEATS2 | 0.600875 | 5 | 0 | 4 |
| EFR3A | RIMS3 | 0.600474 | 4 | 0 | 3 |
| EFR3A | BEND3 | 0.595159 | 3 | 0 | 3 |
For details and further investigation, click here
