TMEM260

 

Full name: transmembrane protein 260 Alias Symbol: FLJ20392
Type: protein-coding gene Cytoband: 14q22.3
Entrez ID: 54916 HGNC ID: HGNC:20185 Ensembl Gene: ENSG00000070269 OMIM ID: 617449
Drug and gene relationship at DGIdb

 

Expression of TMEM260:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM260 54916 225675_at 0.7025 0.1541
GSE20347 TMEM260 54916 219757_s_at 0.4999 0.0106
GSE23400 TMEM260 54916 219757_s_at 0.4643 0.0000
GSE26886 TMEM260 54916 225675_at 0.8322 0.0059
GSE29001 TMEM260 54916 219757_s_at 0.7739 0.0718
GSE38129 TMEM260 54916 219757_s_at 0.6332 0.0547
GSE45670 TMEM260 54916 225675_at 0.5959 0.0014
GSE53622 TMEM260 54916 158402 0.7331 0.0000
GSE53624 TMEM260 54916 93889 0.5203 0.0000
GSE63941 TMEM260 54916 219757_s_at 0.4905 0.3263
GSE77861 TMEM260 54916 225675_at 0.3643 0.0991
SRP007169 TMEM260 54916 RNAseq 0.8881 0.0260
SRP008496 TMEM260 54916 RNAseq 1.2610 0.0000
SRP064894 TMEM260 54916 RNAseq 0.7705 0.0000
SRP133303 TMEM260 54916 RNAseq 0.4234 0.0420
SRP159526 TMEM260 54916 RNAseq 0.3233 0.0528
SRP193095 TMEM260 54916 RNAseq 0.2589 0.0084
SRP219564 TMEM260 54916 RNAseq 0.7378 0.0104

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by TMEM260 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of TMEM260:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM260 54916 8 3 19
GSE20123 TMEM260 54916 8 3 19
GSE43470 TMEM260 54916 9 2 32
GSE46452 TMEM260 54916 16 3 40
GSE47630 TMEM260 54916 11 10 19
GSE54993 TMEM260 54916 3 8 59
GSE54994 TMEM260 54916 19 4 30
GSE60625 TMEM260 54916 0 2 9
GSE74703 TMEM260 54916 8 2 26
GSE74704 TMEM260 54916 3 2 15
TCGA TMEM260 54916 32 14 50

Total number of gains: 117; Total number of losses: 53; Total Number of normals: 318.  

 

Somatic mutations of TMEM260:

 

Generating mutation plots.

 

Highly correlated genes for TMEM260:

 

Showing top 20/829 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM260GNPNAT10.760507303
TMEM260TNFAIP8L10.721306404
TMEM260SPATA170.711749303
TMEM260WDR50.705671404
TMEM260ZNF2840.697746303
TMEM260LRRC580.695124303
TMEM260BCL11A0.691589303
TMEM260TIGD10.682464404
TMEM260TMTC40.678181404
TMEM260COG20.671561706
TMEM260KBTBD70.670872404
TMEM260ACBD60.669928503
TMEM260TWSG10.668212303
TMEM260GORAB0.667066605
TMEM260RNF40.666884303
TMEM260ZNF7860.66335303
TMEM260ZNF5670.6617303
TMEM260AMMECR1L0.657534404
TMEM260FZD60.656302808
TMEM260DFFA0.655408303

For details and further investigation, click here