| Full name: family with sequence similarity 50 member B | Alias Symbol: D6S2654E|X5L | ||
| Type: protein-coding gene | Cytoband: 6p25.2 | ||
| Entrez ID: 26240 | HGNC ID: HGNC:18789 | Ensembl Gene: ENSG00000145945 | OMIM ID: 614686 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM50B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM50B | 26240 | 205775_at | -0.2935 | 0.7225 | |
| GSE20347 | FAM50B | 26240 | 205775_at | 0.2274 | 0.1864 | |
| GSE23400 | FAM50B | 26240 | 205775_at | 0.1230 | 0.0250 | |
| GSE26886 | FAM50B | 26240 | 205775_at | -0.0118 | 0.9759 | |
| GSE29001 | FAM50B | 26240 | 205775_at | 0.1570 | 0.6789 | |
| GSE38129 | FAM50B | 26240 | 205775_at | 0.0139 | 0.9483 | |
| GSE45670 | FAM50B | 26240 | 205775_at | 0.1866 | 0.4161 | |
| GSE53622 | FAM50B | 26240 | 51844 | -0.4227 | 0.0127 | |
| GSE53624 | FAM50B | 26240 | 51844 | -0.1314 | 0.3404 | |
| GSE63941 | FAM50B | 26240 | 205775_at | -0.8340 | 0.2423 | |
| GSE77861 | FAM50B | 26240 | 205775_at | -0.0387 | 0.8577 | |
| GSE97050 | FAM50B | 26240 | A_23_P8240 | -0.5795 | 0.2248 | |
| SRP007169 | FAM50B | 26240 | RNAseq | 0.4063 | 0.5780 | |
| SRP064894 | FAM50B | 26240 | RNAseq | 0.1623 | 0.5461 | |
| SRP133303 | FAM50B | 26240 | RNAseq | -0.2942 | 0.1882 | |
| SRP159526 | FAM50B | 26240 | RNAseq | 0.3310 | 0.3533 | |
| SRP193095 | FAM50B | 26240 | RNAseq | 0.1258 | 0.4489 | |
| SRP219564 | FAM50B | 26240 | RNAseq | 0.1710 | 0.7874 | |
| TCGA | FAM50B | 26240 | RNAseq | -0.0785 | 0.6464 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM50B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM50B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM50B | 26240 | 4 | 5 | 21 | |
| GSE20123 | FAM50B | 26240 | 4 | 5 | 21 | |
| GSE43470 | FAM50B | 26240 | 8 | 2 | 33 | |
| GSE46452 | FAM50B | 26240 | 1 | 10 | 48 | |
| GSE47630 | FAM50B | 26240 | 7 | 8 | 25 | |
| GSE54993 | FAM50B | 26240 | 1 | 1 | 68 | |
| GSE54994 | FAM50B | 26240 | 10 | 3 | 40 | |
| GSE60625 | FAM50B | 26240 | 0 | 1 | 10 | |
| GSE74703 | FAM50B | 26240 | 7 | 2 | 27 | |
| GSE74704 | FAM50B | 26240 | 2 | 2 | 16 | |
| TCGA | FAM50B | 26240 | 16 | 29 | 51 |
Total number of gains: 60; Total number of losses: 68; Total Number of normals: 360.
Somatic mutations of FAM50B:
Generating mutation plots.
Highly correlated genes for FAM50B:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM50B | REPS2 | 0.663037 | 3 | 0 | 3 |
| FAM50B | ZNF605 | 0.639233 | 4 | 0 | 3 |
| FAM50B | ACSL6 | 0.634716 | 3 | 0 | 3 |
| FAM50B | ISCU | 0.625558 | 5 | 0 | 3 |
| FAM50B | ZNF227 | 0.625242 | 3 | 0 | 3 |
| FAM50B | RAI2 | 0.621466 | 5 | 0 | 3 |
| FAM50B | RYR2 | 0.61129 | 4 | 0 | 3 |
| FAM50B | ZNF606 | 0.602063 | 4 | 0 | 3 |
| FAM50B | ZNF84 | 0.593454 | 4 | 0 | 3 |
| FAM50B | CAND2 | 0.586463 | 4 | 0 | 3 |
| FAM50B | RANBP3 | 0.580251 | 4 | 0 | 3 |
| FAM50B | EPM2A | 0.571438 | 4 | 0 | 3 |
| FAM50B | CSRP1 | 0.570183 | 3 | 0 | 3 |
| FAM50B | USP20 | 0.566231 | 4 | 0 | 4 |
| FAM50B | ARHGEF26 | 0.561373 | 5 | 0 | 4 |
| FAM50B | RBM4B | 0.560397 | 3 | 0 | 3 |
| FAM50B | ZNF415 | 0.549204 | 5 | 0 | 3 |
| FAM50B | DCLK1 | 0.548015 | 4 | 0 | 3 |
| FAM50B | GNA11 | 0.546315 | 4 | 0 | 3 |
| FAM50B | ZNF32 | 0.54404 | 6 | 0 | 3 |
For details and further investigation, click here
