| Full name: pre-mRNA processing factor 18 | Alias Symbol: hPrp18 | ||
| Type: protein-coding gene | Cytoband: 10p13 | ||
| Entrez ID: 8559 | HGNC ID: HGNC:17351 | Ensembl Gene: ENSG00000165630 | OMIM ID: 604993 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPF18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPF18 | 8559 | 221547_at | -0.4101 | 0.2492 | |
| GSE20347 | PRPF18 | 8559 | 221547_at | -0.1109 | 0.6186 | |
| GSE23400 | PRPF18 | 8559 | 221546_at | -0.1594 | 0.0008 | |
| GSE26886 | PRPF18 | 8559 | 221547_at | -0.4396 | 0.0363 | |
| GSE29001 | PRPF18 | 8559 | 221547_at | 0.1219 | 0.7609 | |
| GSE38129 | PRPF18 | 8559 | 221547_at | 0.0870 | 0.6362 | |
| GSE45670 | PRPF18 | 8559 | 221547_at | -0.0941 | 0.5551 | |
| GSE53622 | PRPF18 | 8559 | 39387 | -0.2819 | 0.0000 | |
| GSE53624 | PRPF18 | 8559 | 39387 | -0.0713 | 0.3750 | |
| GSE63941 | PRPF18 | 8559 | 221547_at | -0.4466 | 0.2807 | |
| GSE77861 | PRPF18 | 8559 | 221547_at | -0.3858 | 0.2178 | |
| GSE97050 | PRPF18 | 8559 | A_32_P59811 | -0.8286 | 0.0903 | |
| SRP007169 | PRPF18 | 8559 | RNAseq | -0.6077 | 0.1098 | |
| SRP008496 | PRPF18 | 8559 | RNAseq | -0.4881 | 0.0171 | |
| SRP064894 | PRPF18 | 8559 | RNAseq | -0.2095 | 0.0960 | |
| SRP133303 | PRPF18 | 8559 | RNAseq | -0.1605 | 0.2426 | |
| SRP159526 | PRPF18 | 8559 | RNAseq | -0.2201 | 0.5105 | |
| SRP193095 | PRPF18 | 8559 | RNAseq | -0.3579 | 0.0004 | |
| SRP219564 | PRPF18 | 8559 | RNAseq | -0.4050 | 0.2966 | |
| TCGA | PRPF18 | 8559 | RNAseq | -0.0364 | 0.5221 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRPF18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPF18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPF18 | 8559 | 3 | 8 | 19 | |
| GSE20123 | PRPF18 | 8559 | 3 | 7 | 20 | |
| GSE43470 | PRPF18 | 8559 | 3 | 5 | 35 | |
| GSE46452 | PRPF18 | 8559 | 1 | 14 | 44 | |
| GSE47630 | PRPF18 | 8559 | 6 | 14 | 20 | |
| GSE54993 | PRPF18 | 8559 | 11 | 0 | 59 | |
| GSE54994 | PRPF18 | 8559 | 4 | 9 | 40 | |
| GSE60625 | PRPF18 | 8559 | 0 | 0 | 11 | |
| GSE74703 | PRPF18 | 8559 | 2 | 3 | 31 | |
| GSE74704 | PRPF18 | 8559 | 0 | 6 | 14 | |
| TCGA | PRPF18 | 8559 | 20 | 24 | 52 |
Total number of gains: 53; Total number of losses: 90; Total Number of normals: 345.
Somatic mutations of PRPF18:
Generating mutation plots.
Highly correlated genes for PRPF18:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPF18 | TRAPPC11 | 0.668213 | 5 | 0 | 5 |
| PRPF18 | TMEM14C | 0.654615 | 4 | 0 | 4 |
| PRPF18 | EMC2 | 0.626563 | 4 | 0 | 3 |
| PRPF18 | SDHD | 0.61918 | 5 | 0 | 5 |
| PRPF18 | AHNAK | 0.616983 | 4 | 0 | 3 |
| PRPF18 | ATP6V1G1 | 0.61556 | 4 | 0 | 3 |
| PRPF18 | KRT4 | 0.614305 | 4 | 0 | 3 |
| PRPF18 | TMEM251 | 0.614237 | 3 | 0 | 3 |
| PRPF18 | ZSCAN18 | 0.607511 | 3 | 0 | 3 |
| PRPF18 | SLK | 0.604637 | 5 | 0 | 4 |
| PRPF18 | EPC1 | 0.60166 | 5 | 0 | 5 |
| PRPF18 | EMP1 | 0.601605 | 5 | 0 | 3 |
| PRPF18 | SERAC1 | 0.601158 | 4 | 0 | 3 |
| PRPF18 | ZNF84 | 0.596562 | 3 | 0 | 3 |
| PRPF18 | CCDC186 | 0.591252 | 5 | 0 | 4 |
| PRPF18 | GHITM | 0.590031 | 8 | 0 | 6 |
| PRPF18 | CDKN2AIP | 0.586786 | 4 | 0 | 3 |
| PRPF18 | ETFA | 0.576667 | 8 | 0 | 6 |
| PRPF18 | RNF170 | 0.574462 | 5 | 0 | 5 |
| PRPF18 | KRBOX1 | 0.574364 | 3 | 0 | 3 |
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