ZNF823

 

Full name: zinc finger protein 823 Alias Symbol: HSZFP36
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 55552 HGNC ID: HGNC:30936 Ensembl Gene: ENSG00000197933 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of ZNF823:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF823 55552 229732_at -1.2055 0.1683
GSE26886 ZNF823 55552 229732_at -1.3823 0.0000
GSE45670 ZNF823 55552 229732_at -0.4889 0.0682
GSE53622 ZNF823 55552 18142 -0.6502 0.0000
GSE53624 ZNF823 55552 18142 -0.8895 0.0000
GSE63941 ZNF823 55552 229732_at -0.0475 0.9523
GSE77861 ZNF823 55552 229732_at -1.3800 0.0032
GSE97050 ZNF823 55552 A_23_P39050 -0.1900 0.5667
SRP007169 ZNF823 55552 RNAseq -2.0869 0.0000
SRP008496 ZNF823 55552 RNAseq -2.1671 0.0000
SRP064894 ZNF823 55552 RNAseq -1.4393 0.0000
SRP133303 ZNF823 55552 RNAseq -1.3012 0.0000
SRP159526 ZNF823 55552 RNAseq -1.6009 0.0000
SRP193095 ZNF823 55552 RNAseq -1.7586 0.0000
SRP219564 ZNF823 55552 RNAseq -1.4239 0.0104
TCGA ZNF823 55552 RNAseq -0.1873 0.0160

Upregulated datasets: 0; Downregulated datasets: 9.  


 

Survival by ZNF823 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZNF823:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF823 55552 4 2 24
GSE20123 ZNF823 55552 3 1 26
GSE43470 ZNF823 55552 2 6 35
GSE46452 ZNF823 55552 47 1 11
GSE47630 ZNF823 55552 4 7 29
GSE54993 ZNF823 55552 16 3 51
GSE54994 ZNF823 55552 6 13 34
GSE60625 ZNF823 55552 9 0 2
GSE74703 ZNF823 55552 2 4 30
GSE74704 ZNF823 55552 0 1 19
TCGA ZNF823 55552 16 12 68

Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.  


 

Somatic mutations of ZNF823:

 

Generating mutation plots.

 

Highly correlated genes for ZNF823:

 

Showing top 20/1775 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF823GBP60.830686404
ZNF823ABHD50.816734707
ZNF823ACPP0.810526606
ZNF823C12orf290.807896606
ZNF823SPTLC10.798446707
ZNF823CCNYL10.795757505
ZNF823SCP20.792878707
ZNF823NEBL0.787881606
ZNF823MNS10.784944303
ZNF823FRMD4B0.784164707
ZNF823SOCS60.783828505
ZNF823PADI10.78243404
ZNF823SASH10.781577707
ZNF823VPS4B0.781186707
ZNF823GOLGA40.779799505
ZNF823CCDC60.778493706
ZNF823MFSD50.778151707
ZNF823RBM200.777534404
ZNF823ZFC3H10.777284303
ZNF823PPFIBP20.776377707

For details and further investigation, click here