| Full name: family with sequence similarity 221 member A | Alias Symbol: FLJ45875|MGC72075|DKFZp686F0810 | ||
| Type: protein-coding gene | Cytoband: 7p15.3 | ||
| Entrez ID: 340277 | HGNC ID: HGNC:27977 | Ensembl Gene: ENSG00000188732 | OMIM ID: |
Expression of FAM221A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM221A | 340277 | 228600_x_at | -0.8740 | 0.3310 | |
| GSE26886 | FAM221A | 340277 | 228600_x_at | -1.7648 | 0.0001 | |
| GSE45670 | FAM221A | 340277 | 228600_x_at | -1.5340 | 0.0036 | |
| GSE53622 | FAM221A | 340277 | 89636 | -1.3172 | 0.0000 | |
| GSE53624 | FAM221A | 340277 | 89636 | -1.7424 | 0.0000 | |
| GSE63941 | FAM221A | 340277 | 228600_x_at | -0.0561 | 0.9697 | |
| GSE77861 | FAM221A | 340277 | 228600_x_at | -1.5305 | 0.0027 | |
| SRP007169 | FAM221A | 340277 | RNAseq | -1.8986 | 0.0003 | |
| SRP064894 | FAM221A | 340277 | RNAseq | -1.5839 | 0.0000 | |
| SRP133303 | FAM221A | 340277 | RNAseq | -1.3082 | 0.0004 | |
| SRP159526 | FAM221A | 340277 | RNAseq | -1.8164 | 0.0000 | |
| SRP193095 | FAM221A | 340277 | RNAseq | -1.2320 | 0.0004 | |
| SRP219564 | FAM221A | 340277 | RNAseq | -1.8821 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by FAM221A expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of FAM221A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM221A | 340277 | 17 | 1 | 12 | |
| GSE20123 | FAM221A | 340277 | 17 | 1 | 12 | |
| GSE43470 | FAM221A | 340277 | 4 | 0 | 39 | |
| GSE46452 | FAM221A | 340277 | 10 | 2 | 47 | |
| GSE47630 | FAM221A | 340277 | 9 | 1 | 30 | |
| GSE54993 | FAM221A | 340277 | 0 | 6 | 64 | |
| GSE54994 | FAM221A | 340277 | 20 | 2 | 31 | |
| GSE60625 | FAM221A | 340277 | 0 | 0 | 11 | |
| GSE74703 | FAM221A | 340277 | 4 | 0 | 32 | |
| GSE74704 | FAM221A | 340277 | 11 | 1 | 8 | |
| TCGA | FAM221A | 340277 | 56 | 4 | 36 |
Total number of gains: 148; Total number of losses: 18; Total Number of normals: 322.
Somatic mutations of FAM221A:
Generating mutation plots.
Highly correlated genes for FAM221A:
Showing top 20/1187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM221A | GPD1L | 0.780601 | 6 | 0 | 6 |
| FAM221A | ZNF93 | 0.779501 | 4 | 0 | 4 |
| FAM221A | SASH1 | 0.762859 | 6 | 0 | 6 |
| FAM221A | ZNF675 | 0.762856 | 4 | 0 | 4 |
| FAM221A | C5orf66-AS1 | 0.760847 | 6 | 0 | 6 |
| FAM221A | VSIG2 | 0.758124 | 6 | 0 | 6 |
| FAM221A | EPB41L4A | 0.757022 | 4 | 0 | 4 |
| FAM221A | STRADB | 0.757015 | 6 | 0 | 6 |
| FAM221A | IKZF2 | 0.756046 | 6 | 0 | 6 |
| FAM221A | EXPH5 | 0.75394 | 6 | 0 | 6 |
| FAM221A | CAB39L | 0.75384 | 6 | 0 | 6 |
| FAM221A | UBL3 | 0.751243 | 6 | 0 | 6 |
| FAM221A | SMIM14 | 0.750021 | 5 | 0 | 5 |
| FAM221A | FAM3B | 0.749263 | 6 | 0 | 6 |
| FAM221A | MPC1 | 0.747916 | 6 | 0 | 6 |
| FAM221A | HPGD | 0.746379 | 6 | 0 | 6 |
| FAM221A | SPSB3 | 0.742903 | 6 | 0 | 6 |
| FAM221A | KIAA1211L | 0.740368 | 6 | 0 | 6 |
| FAM221A | NT5C2 | 0.740083 | 6 | 0 | 6 |
| FAM221A | SCP2 | 0.739381 | 6 | 0 | 6 |
For details and further investigation, click here
