| Full name: zinc finger protein 853 | Alias Symbol: DKFZp434J1015 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 54753 | HGNC ID: HGNC:21767 | Ensembl Gene: ENSG00000236609 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF853:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF853 | 54753 | 228270_at | -0.2226 | 0.3893 | |
| GSE26886 | ZNF853 | 54753 | 228270_at | 0.0141 | 0.9411 | |
| GSE45670 | ZNF853 | 54753 | 228270_at | -0.0380 | 0.6813 | |
| GSE53622 | ZNF853 | 54753 | 3884 | -0.0936 | 0.4175 | |
| GSE53624 | ZNF853 | 54753 | 3884 | 0.2946 | 0.0003 | |
| GSE63941 | ZNF853 | 54753 | 228270_at | 0.1226 | 0.7036 | |
| GSE77861 | ZNF853 | 54753 | 228270_at | -0.0850 | 0.5495 | |
| SRP007169 | ZNF853 | 54753 | RNAseq | 0.7368 | 0.3665 | |
| SRP064894 | ZNF853 | 54753 | RNAseq | 0.1800 | 0.6744 | |
| SRP133303 | ZNF853 | 54753 | RNAseq | -0.5201 | 0.1600 | |
| SRP159526 | ZNF853 | 54753 | RNAseq | 1.1442 | 0.0019 | |
| SRP219564 | ZNF853 | 54753 | RNAseq | -0.5125 | 0.5006 | |
| TCGA | ZNF853 | 54753 | RNAseq | -0.4654 | 0.0291 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZNF853 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF853:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF853 | 54753 | 14 | 1 | 15 | |
| GSE20123 | ZNF853 | 54753 | 14 | 1 | 15 | |
| GSE43470 | ZNF853 | 54753 | 7 | 1 | 35 | |
| GSE46452 | ZNF853 | 54753 | 13 | 1 | 45 | |
| GSE47630 | ZNF853 | 54753 | 9 | 1 | 30 | |
| GSE54993 | ZNF853 | 54753 | 0 | 6 | 64 | |
| GSE54994 | ZNF853 | 54753 | 20 | 1 | 32 | |
| GSE60625 | ZNF853 | 54753 | 0 | 0 | 11 | |
| GSE74703 | ZNF853 | 54753 | 7 | 0 | 29 | |
| GSE74704 | ZNF853 | 54753 | 9 | 0 | 11 | |
| TCGA | ZNF853 | 54753 | 56 | 4 | 36 |
Total number of gains: 149; Total number of losses: 16; Total Number of normals: 323.
Somatic mutations of ZNF853:
Generating mutation plots.
Highly correlated genes for ZNF853:
Showing top 20/171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF853 | DNAI1 | 0.737797 | 3 | 0 | 3 |
| ZNF853 | RBAKDN | 0.693064 | 3 | 0 | 3 |
| ZNF853 | G6PC2 | 0.688361 | 3 | 0 | 3 |
| ZNF853 | IQCJ-SCHIP1-AS1 | 0.686459 | 3 | 0 | 3 |
| ZNF853 | MPL | 0.683519 | 4 | 0 | 3 |
| ZNF853 | ZBTB10 | 0.68073 | 3 | 0 | 3 |
| ZNF853 | RNF150 | 0.673023 | 3 | 0 | 3 |
| ZNF853 | VWA5B1 | 0.672187 | 3 | 0 | 3 |
| ZNF853 | RETN | 0.670751 | 3 | 0 | 3 |
| ZNF853 | ADARB1 | 0.669501 | 3 | 0 | 3 |
| ZNF853 | LINGO3 | 0.665997 | 3 | 0 | 3 |
| ZNF853 | KLHL17 | 0.665108 | 3 | 0 | 3 |
| ZNF853 | MUC8 | 0.664773 | 3 | 0 | 3 |
| ZNF853 | NACAD | 0.662135 | 4 | 0 | 4 |
| ZNF853 | HRH2 | 0.662127 | 3 | 0 | 3 |
| ZNF853 | C9orf50 | 0.658704 | 3 | 0 | 3 |
| ZNF853 | PKD2L1 | 0.655695 | 3 | 0 | 3 |
| ZNF853 | INSL3 | 0.655384 | 4 | 0 | 4 |
| ZNF853 | LINC00544 | 0.65528 | 4 | 0 | 3 |
| ZNF853 | LONRF2 | 0.653096 | 3 | 0 | 3 |
For details and further investigation, click here
