| Full name: NAC alpha domain containing | Alias Symbol: KIAA0363 | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 23148 | HGNC ID: HGNC:22196 | Ensembl Gene: ENSG00000136274 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NACAD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NACAD | 23148 | 213630_at | -0.4549 | 0.4554 | |
| GSE20347 | NACAD | 23148 | 213630_at | -0.0037 | 0.9700 | |
| GSE23400 | NACAD | 23148 | 213630_at | -0.2743 | 0.0000 | |
| GSE26886 | NACAD | 23148 | 213630_at | 0.4352 | 0.0019 | |
| GSE29001 | NACAD | 23148 | 213630_at | -0.0039 | 0.9832 | |
| GSE38129 | NACAD | 23148 | 213630_at | -0.3051 | 0.0741 | |
| GSE45670 | NACAD | 23148 | 213630_at | -0.3661 | 0.0037 | |
| GSE53622 | NACAD | 23148 | 18543 | 0.1194 | 0.3106 | |
| GSE53624 | NACAD | 23148 | 18543 | 0.1646 | 0.0194 | |
| GSE63941 | NACAD | 23148 | 213630_at | -0.8559 | 0.0108 | |
| GSE77861 | NACAD | 23148 | 213630_at | -0.1685 | 0.1892 | |
| GSE97050 | NACAD | 23148 | A_23_P93938 | -0.3072 | 0.5458 | |
| SRP064894 | NACAD | 23148 | RNAseq | 1.0119 | 0.0200 | |
| SRP133303 | NACAD | 23148 | RNAseq | 0.0603 | 0.8892 | |
| SRP159526 | NACAD | 23148 | RNAseq | 0.3028 | 0.5930 | |
| SRP219564 | NACAD | 23148 | RNAseq | -0.5374 | 0.4882 | |
| TCGA | NACAD | 23148 | RNAseq | -0.5902 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NACAD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NACAD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NACAD | 23148 | 13 | 0 | 17 | |
| GSE20123 | NACAD | 23148 | 12 | 0 | 18 | |
| GSE43470 | NACAD | 23148 | 4 | 0 | 39 | |
| GSE46452 | NACAD | 23148 | 11 | 1 | 47 | |
| GSE47630 | NACAD | 23148 | 8 | 1 | 31 | |
| GSE54993 | NACAD | 23148 | 0 | 8 | 62 | |
| GSE54994 | NACAD | 23148 | 16 | 3 | 34 | |
| GSE60625 | NACAD | 23148 | 0 | 0 | 11 | |
| GSE74703 | NACAD | 23148 | 4 | 0 | 32 | |
| GSE74704 | NACAD | 23148 | 6 | 0 | 14 | |
| TCGA | NACAD | 23148 | 50 | 7 | 39 |
Total number of gains: 124; Total number of losses: 20; Total Number of normals: 344.
Somatic mutations of NACAD:
Generating mutation plots.
Highly correlated genes for NACAD:
Showing top 20/738 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NACAD | SPATA2L | 0.768993 | 3 | 0 | 3 |
| NACAD | SHROOM1 | 0.746817 | 3 | 0 | 3 |
| NACAD | HSD17B14 | 0.732642 | 3 | 0 | 3 |
| NACAD | GRIN2A | 0.727728 | 4 | 0 | 4 |
| NACAD | MAGEE1 | 0.724464 | 3 | 0 | 3 |
| NACAD | GRK4 | 0.718586 | 4 | 0 | 4 |
| NACAD | TTLL9 | 0.718257 | 3 | 0 | 3 |
| NACAD | SNX21 | 0.713699 | 3 | 0 | 3 |
| NACAD | JSRP1 | 0.7134 | 3 | 0 | 3 |
| NACAD | MYOC | 0.712523 | 4 | 0 | 4 |
| NACAD | ITGA2B | 0.711148 | 4 | 0 | 4 |
| NACAD | SFRP5 | 0.708571 | 3 | 0 | 3 |
| NACAD | PGM5-AS1 | 0.706607 | 3 | 0 | 3 |
| NACAD | TCEAL7 | 0.706533 | 5 | 0 | 5 |
| NACAD | TBXA2R | 0.706344 | 4 | 0 | 4 |
| NACAD | ZNF524 | 0.70576 | 4 | 0 | 3 |
| NACAD | CCDC89 | 0.705163 | 3 | 0 | 3 |
| NACAD | CARNS1 | 0.704661 | 3 | 0 | 3 |
| NACAD | MGAT5B | 0.699711 | 3 | 0 | 3 |
| NACAD | ALKBH5 | 0.696816 | 3 | 0 | 3 |
For details and further investigation, click here
