| Full name: glucose-6-phosphatase catalytic subunit 2 | Alias Symbol: IGRP | ||
| Type: protein-coding gene | Cytoband: 2q31.1 | ||
| Entrez ID: 57818 | HGNC ID: HGNC:28906 | Ensembl Gene: ENSG00000152254 | OMIM ID: 608058 |
| Drug and gene relationship at DGIdb | |||
G6PC2 involved pathways:
Expression of G6PC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | G6PC2 | 57818 | 221453_at | -0.1724 | 0.4448 | |
| GSE20347 | G6PC2 | 57818 | 221453_at | -0.0454 | 0.6332 | |
| GSE23400 | G6PC2 | 57818 | 221453_at | -0.1440 | 0.0011 | |
| GSE26886 | G6PC2 | 57818 | 221453_at | -0.1192 | 0.3129 | |
| GSE29001 | G6PC2 | 57818 | 221453_at | -0.2253 | 0.1805 | |
| GSE38129 | G6PC2 | 57818 | 221453_at | -0.1244 | 0.2215 | |
| GSE45670 | G6PC2 | 57818 | 221453_at | -0.0487 | 0.6743 | |
| GSE53622 | G6PC2 | 57818 | 59918 | -0.0216 | 0.8996 | |
| GSE53624 | G6PC2 | 57818 | 59918 | -0.1293 | 0.1167 | |
| GSE63941 | G6PC2 | 57818 | 221453_at | 0.1590 | 0.2726 | |
| GSE77861 | G6PC2 | 57818 | 221453_at | -0.1216 | 0.3278 | |
| SRP133303 | G6PC2 | 57818 | RNAseq | -0.1412 | 0.5555 | |
| TCGA | G6PC2 | 57818 | RNAseq | -4.2151 | 0.0064 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by G6PC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of G6PC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | G6PC2 | 57818 | 6 | 0 | 24 | |
| GSE20123 | G6PC2 | 57818 | 6 | 0 | 24 | |
| GSE43470 | G6PC2 | 57818 | 5 | 1 | 37 | |
| GSE46452 | G6PC2 | 57818 | 1 | 4 | 54 | |
| GSE47630 | G6PC2 | 57818 | 5 | 3 | 32 | |
| GSE54993 | G6PC2 | 57818 | 0 | 5 | 65 | |
| GSE54994 | G6PC2 | 57818 | 11 | 2 | 40 | |
| GSE60625 | G6PC2 | 57818 | 0 | 3 | 8 | |
| GSE74703 | G6PC2 | 57818 | 4 | 1 | 31 | |
| GSE74704 | G6PC2 | 57818 | 3 | 0 | 17 | |
| TCGA | G6PC2 | 57818 | 24 | 10 | 62 |
Total number of gains: 65; Total number of losses: 29; Total Number of normals: 394.
Somatic mutations of G6PC2:
Generating mutation plots.
Highly correlated genes for G6PC2:
Showing top 20/1352 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| G6PC2 | DAB1 | 0.776367 | 4 | 0 | 4 |
| G6PC2 | EPOR | 0.763666 | 6 | 0 | 6 |
| G6PC2 | AQP6 | 0.753122 | 4 | 0 | 4 |
| G6PC2 | SAG | 0.74608 | 4 | 0 | 4 |
| G6PC2 | KHDRBS2 | 0.743424 | 4 | 0 | 4 |
| G6PC2 | GABRR2 | 0.741388 | 4 | 0 | 4 |
| G6PC2 | GRM6 | 0.738373 | 6 | 0 | 6 |
| G6PC2 | EPX | 0.734901 | 4 | 0 | 4 |
| G6PC2 | CYP19A1 | 0.732951 | 4 | 0 | 4 |
| G6PC2 | KRT38 | 0.72443 | 4 | 0 | 4 |
| G6PC2 | HAND1 | 0.723384 | 7 | 0 | 7 |
| G6PC2 | CCDC7 | 0.716784 | 5 | 0 | 5 |
| G6PC2 | EDA2R | 0.71651 | 6 | 0 | 5 |
| G6PC2 | JAK3 | 0.714063 | 5 | 0 | 5 |
| G6PC2 | DRD5 | 0.712071 | 5 | 0 | 5 |
| G6PC2 | CAMK2B | 0.711675 | 7 | 0 | 6 |
| G6PC2 | MVK | 0.709453 | 7 | 0 | 6 |
| G6PC2 | CCDC13 | 0.704514 | 4 | 0 | 4 |
| G6PC2 | FAM163A | 0.704152 | 4 | 0 | 4 |
| G6PC2 | PDE5A | 0.704127 | 3 | 0 | 3 |
For details and further investigation, click here
