| Full name: adenosine deaminase RNA specific B1 | Alias Symbol: ADAR2|DRADA2|ADAR2g|DRABA2|RED1|hRED1|ADAR2a-L1|ADAR2a-L2|ADAR2a-L3|ADAR2a|ADAR2b|ADAR2c|ADAR2d | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 104 | HGNC ID: HGNC:226 | Ensembl Gene: ENSG00000197381 | OMIM ID: 601218 |
| Drug and gene relationship at DGIdb | |||
Expression of ADARB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADARB1 | 104 | 203865_s_at | -1.2076 | 0.2662 | |
| GSE20347 | ADARB1 | 104 | 207999_s_at | 0.0234 | 0.7745 | |
| GSE23400 | ADARB1 | 104 | 203865_s_at | -0.5390 | 0.0087 | |
| GSE26886 | ADARB1 | 104 | 209979_at | 0.3570 | 0.0076 | |
| GSE29001 | ADARB1 | 104 | 203865_s_at | 0.3680 | 0.4673 | |
| GSE38129 | ADARB1 | 104 | 203865_s_at | -0.8324 | 0.0704 | |
| GSE45670 | ADARB1 | 104 | 203865_s_at | -0.9660 | 0.0050 | |
| GSE53622 | ADARB1 | 104 | 92327 | -0.5677 | 0.0007 | |
| GSE53624 | ADARB1 | 104 | 144278 | -0.4252 | 0.0003 | |
| GSE63941 | ADARB1 | 104 | 203865_s_at | -0.3226 | 0.6525 | |
| GSE77861 | ADARB1 | 104 | 209979_at | -0.0453 | 0.8550 | |
| GSE97050 | ADARB1 | 104 | A_23_P211207 | -1.2071 | 0.1657 | |
| SRP007169 | ADARB1 | 104 | RNAseq | 0.9755 | 0.0929 | |
| SRP064894 | ADARB1 | 104 | RNAseq | 0.6560 | 0.0119 | |
| SRP133303 | ADARB1 | 104 | RNAseq | -0.8219 | 0.0044 | |
| SRP159526 | ADARB1 | 104 | RNAseq | -0.1085 | 0.8225 | |
| SRP193095 | ADARB1 | 104 | RNAseq | 1.0316 | 0.0000 | |
| SRP219564 | ADARB1 | 104 | RNAseq | -1.2644 | 0.2110 | |
| TCGA | ADARB1 | 104 | RNAseq | -0.3605 | 0.0018 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ADARB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADARB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADARB1 | 104 | 2 | 8 | 20 | |
| GSE20123 | ADARB1 | 104 | 2 | 8 | 20 | |
| GSE43470 | ADARB1 | 104 | 0 | 13 | 30 | |
| GSE46452 | ADARB1 | 104 | 1 | 21 | 37 | |
| GSE47630 | ADARB1 | 104 | 6 | 17 | 17 | |
| GSE54993 | ADARB1 | 104 | 8 | 1 | 61 | |
| GSE54994 | ADARB1 | 104 | 5 | 8 | 40 | |
| GSE60625 | ADARB1 | 104 | 0 | 0 | 11 | |
| GSE74703 | ADARB1 | 104 | 0 | 10 | 26 | |
| GSE74704 | ADARB1 | 104 | 1 | 4 | 15 | |
| TCGA | ADARB1 | 104 | 9 | 38 | 49 |
Total number of gains: 34; Total number of losses: 128; Total Number of normals: 326.
Somatic mutations of ADARB1:
Generating mutation plots.
Highly correlated genes for ADARB1:
Showing top 20/1033 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADARB1 | CHADL | 0.860341 | 3 | 0 | 3 |
| ADARB1 | FIBIN | 0.822058 | 3 | 0 | 3 |
| ADARB1 | DDR2 | 0.796166 | 7 | 0 | 7 |
| ADARB1 | PLN | 0.794758 | 7 | 0 | 7 |
| ADARB1 | SLIT2 | 0.790912 | 7 | 0 | 7 |
| ADARB1 | FLNA | 0.787126 | 7 | 0 | 7 |
| ADARB1 | ARHGAP6 | 0.786265 | 7 | 0 | 7 |
| ADARB1 | AFF3 | 0.783889 | 3 | 0 | 3 |
| ADARB1 | TLN1 | 0.782529 | 6 | 0 | 6 |
| ADARB1 | ILK | 0.780279 | 8 | 0 | 7 |
| ADARB1 | COX7A1 | 0.776216 | 8 | 0 | 8 |
| ADARB1 | PKIG | 0.773632 | 8 | 0 | 7 |
| ADARB1 | TMOD1 | 0.770588 | 6 | 0 | 6 |
| ADARB1 | ADAMTS5 | 0.769899 | 7 | 0 | 7 |
| ADARB1 | MRVI1 | 0.769353 | 5 | 0 | 5 |
| ADARB1 | DMD | 0.768473 | 7 | 0 | 7 |
| ADARB1 | CFL2 | 0.768377 | 5 | 0 | 5 |
| ADARB1 | GPM6A | 0.767013 | 5 | 0 | 5 |
| ADARB1 | ARMC9 | 0.762408 | 4 | 0 | 4 |
| ADARB1 | CACNA1C | 0.760519 | 5 | 0 | 4 |
For details and further investigation, click here
