| Full name: zinc finger ZZ-type and EF-hand domain containing 1 | Alias Symbol: KIAA0399|ZZZ4|FLJ10821 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 23140 | HGNC ID: HGNC:29027 | Ensembl Gene: ENSG00000074755 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZZEF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZZEF1 | 23140 | 212601_at | -0.2103 | 0.5211 | |
| GSE20347 | ZZEF1 | 23140 | 212601_at | -0.2786 | 0.0078 | |
| GSE23400 | ZZEF1 | 23140 | 212601_at | -0.2084 | 0.0002 | |
| GSE26886 | ZZEF1 | 23140 | 212601_at | 0.9210 | 0.0000 | |
| GSE29001 | ZZEF1 | 23140 | 212601_at | -0.1119 | 0.6977 | |
| GSE38129 | ZZEF1 | 23140 | 212601_at | -0.4084 | 0.0001 | |
| GSE45670 | ZZEF1 | 23140 | 212601_at | -0.2345 | 0.0404 | |
| GSE53622 | ZZEF1 | 23140 | 49294 | -0.6931 | 0.0000 | |
| GSE53624 | ZZEF1 | 23140 | 49294 | -0.4450 | 0.0000 | |
| GSE63941 | ZZEF1 | 23140 | 212601_at | -0.2623 | 0.4525 | |
| GSE77861 | ZZEF1 | 23140 | 212601_at | 0.1084 | 0.7683 | |
| GSE97050 | ZZEF1 | 23140 | A_24_P282108 | -0.6121 | 0.1372 | |
| SRP007169 | ZZEF1 | 23140 | RNAseq | -0.3569 | 0.3573 | |
| SRP008496 | ZZEF1 | 23140 | RNAseq | -0.1850 | 0.4096 | |
| SRP064894 | ZZEF1 | 23140 | RNAseq | -0.6045 | 0.0022 | |
| SRP133303 | ZZEF1 | 23140 | RNAseq | -0.5534 | 0.0001 | |
| SRP159526 | ZZEF1 | 23140 | RNAseq | -0.6137 | 0.0001 | |
| SRP193095 | ZZEF1 | 23140 | RNAseq | -0.2760 | 0.0824 | |
| SRP219564 | ZZEF1 | 23140 | RNAseq | 0.0013 | 0.9973 | |
| TCGA | ZZEF1 | 23140 | RNAseq | -0.2494 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZZEF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZZEF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZZEF1 | 23140 | 5 | 2 | 23 | |
| GSE20123 | ZZEF1 | 23140 | 5 | 3 | 22 | |
| GSE43470 | ZZEF1 | 23140 | 1 | 6 | 36 | |
| GSE46452 | ZZEF1 | 23140 | 34 | 1 | 24 | |
| GSE47630 | ZZEF1 | 23140 | 7 | 1 | 32 | |
| GSE54993 | ZZEF1 | 23140 | 4 | 3 | 63 | |
| GSE54994 | ZZEF1 | 23140 | 5 | 9 | 39 | |
| GSE60625 | ZZEF1 | 23140 | 4 | 0 | 7 | |
| GSE74703 | ZZEF1 | 23140 | 1 | 3 | 32 | |
| GSE74704 | ZZEF1 | 23140 | 3 | 1 | 16 | |
| TCGA | ZZEF1 | 23140 | 18 | 21 | 57 |
Total number of gains: 87; Total number of losses: 50; Total Number of normals: 351.
Somatic mutations of ZZEF1:
Generating mutation plots.
Highly correlated genes for ZZEF1:
Showing top 20/309 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZZEF1 | PEX14 | 0.814509 | 3 | 0 | 3 |
| ZZEF1 | RIMKLB | 0.790133 | 3 | 0 | 3 |
| ZZEF1 | GLI3 | 0.7827 | 3 | 0 | 3 |
| ZZEF1 | ZNF438 | 0.769517 | 3 | 0 | 3 |
| ZZEF1 | PIP4K2B | 0.755475 | 3 | 0 | 3 |
| ZZEF1 | C11orf49 | 0.755138 | 3 | 0 | 3 |
| ZZEF1 | CHD3 | 0.753526 | 4 | 0 | 4 |
| ZZEF1 | TTLL1 | 0.740402 | 3 | 0 | 3 |
| ZZEF1 | PREX2 | 0.732456 | 3 | 0 | 3 |
| ZZEF1 | STARD3NL | 0.726954 | 3 | 0 | 3 |
| ZZEF1 | SRGAP2 | 0.722112 | 4 | 0 | 3 |
| ZZEF1 | TTF1 | 0.720503 | 3 | 0 | 3 |
| ZZEF1 | ZNF747 | 0.718688 | 3 | 0 | 3 |
| ZZEF1 | PPIG | 0.70846 | 3 | 0 | 3 |
| ZZEF1 | ZNF814 | 0.705337 | 3 | 0 | 3 |
| ZZEF1 | SERPINF2 | 0.704064 | 3 | 0 | 3 |
| ZZEF1 | BVES | 0.700263 | 4 | 0 | 4 |
| ZZEF1 | COMMD7 | 0.699601 | 3 | 0 | 3 |
| ZZEF1 | TMEM181 | 0.698536 | 3 | 0 | 3 |
| ZZEF1 | ERVW-1 | 0.694722 | 3 | 0 | 3 |
For details and further investigation, click here
