| Full name: peroxisomal biogenesis factor 14 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 5195 | HGNC ID: HGNC:8856 | Ensembl Gene: ENSG00000142655 | OMIM ID: 601791 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PEX14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX14 | 5195 | 33760_at | -0.2363 | 0.6089 | |
| GSE20347 | PEX14 | 5195 | 33760_at | -0.1960 | 0.0754 | |
| GSE23400 | PEX14 | 5195 | 203503_s_at | -0.0812 | 0.0621 | |
| GSE26886 | PEX14 | 5195 | 33760_at | 0.8427 | 0.0000 | |
| GSE29001 | PEX14 | 5195 | 203503_s_at | -0.1393 | 0.3536 | |
| GSE38129 | PEX14 | 5195 | 33760_at | -0.1700 | 0.0829 | |
| GSE45670 | PEX14 | 5195 | 33760_at | -0.1197 | 0.2819 | |
| GSE53622 | PEX14 | 5195 | 30902 | 0.1406 | 0.3947 | |
| GSE53624 | PEX14 | 5195 | 30902 | 0.1246 | 0.2393 | |
| GSE63941 | PEX14 | 5195 | 33760_at | 0.6207 | 0.1048 | |
| GSE77861 | PEX14 | 5195 | 33760_at | -0.2316 | 0.0626 | |
| GSE97050 | PEX14 | 5195 | A_23_P160787 | -0.2092 | 0.3764 | |
| SRP007169 | PEX14 | 5195 | RNAseq | -0.0449 | 0.9390 | |
| SRP064894 | PEX14 | 5195 | RNAseq | -0.1275 | 0.5379 | |
| SRP133303 | PEX14 | 5195 | RNAseq | -0.1801 | 0.1608 | |
| SRP159526 | PEX14 | 5195 | RNAseq | -0.3682 | 0.2387 | |
| SRP193095 | PEX14 | 5195 | RNAseq | 0.1109 | 0.1344 | |
| SRP219564 | PEX14 | 5195 | RNAseq | -0.6046 | 0.0522 | |
| TCGA | PEX14 | 5195 | RNAseq | 0.0743 | 0.1962 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PEX14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX14 | 5195 | 0 | 5 | 25 | |
| GSE20123 | PEX14 | 5195 | 0 | 3 | 27 | |
| GSE43470 | PEX14 | 5195 | 7 | 5 | 31 | |
| GSE46452 | PEX14 | 5195 | 7 | 1 | 51 | |
| GSE47630 | PEX14 | 5195 | 8 | 4 | 28 | |
| GSE54993 | PEX14 | 5195 | 3 | 1 | 66 | |
| GSE54994 | PEX14 | 5195 | 11 | 4 | 38 | |
| GSE60625 | PEX14 | 5195 | 0 | 0 | 11 | |
| GSE74703 | PEX14 | 5195 | 6 | 3 | 27 | |
| GSE74704 | PEX14 | 5195 | 0 | 0 | 20 | |
| TCGA | PEX14 | 5195 | 10 | 25 | 61 |
Total number of gains: 52; Total number of losses: 51; Total Number of normals: 385.
Somatic mutations of PEX14:
Generating mutation plots.
Highly correlated genes for PEX14:
Showing top 20/234 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX14 | SAG | 0.82224 | 4 | 0 | 4 |
| PEX14 | ZZEF1 | 0.814509 | 3 | 0 | 3 |
| PEX14 | ZNF358 | 0.788962 | 3 | 0 | 3 |
| PEX14 | TRIM3 | 0.781758 | 3 | 0 | 3 |
| PEX14 | C9orf85 | 0.759761 | 3 | 0 | 3 |
| PEX14 | MYSM1 | 0.750226 | 3 | 0 | 3 |
| PEX14 | POLR2A | 0.748002 | 3 | 0 | 3 |
| PEX14 | PAN3 | 0.739888 | 3 | 0 | 3 |
| PEX14 | MIER2 | 0.730509 | 4 | 0 | 4 |
| PEX14 | MVP | 0.727448 | 3 | 0 | 3 |
| PEX14 | PHRF1 | 0.725371 | 3 | 0 | 3 |
| PEX14 | FAM193A | 0.723742 | 3 | 0 | 3 |
| PEX14 | CCDC12 | 0.723419 | 3 | 0 | 3 |
| PEX14 | ZC3H3 | 0.715322 | 4 | 0 | 4 |
| PEX14 | NADK | 0.715052 | 3 | 0 | 3 |
| PEX14 | TACC2 | 0.714849 | 3 | 0 | 3 |
| PEX14 | ZNF287 | 0.713784 | 3 | 0 | 3 |
| PEX14 | C2orf76 | 0.700858 | 3 | 0 | 3 |
| PEX14 | TTC39B | 0.700619 | 3 | 0 | 3 |
| PEX14 | ZNF70 | 0.697624 | 3 | 0 | 3 |
For details and further investigation, click here
