| Full name: serpin family F member 2 | Alias Symbol: API|ALPHA-2-PI|A2AP|AAP | ||
| Type: protein-coding gene | Cytoband: 17p13.3 | ||
| Entrez ID: 5345 | HGNC ID: HGNC:9075 | Ensembl Gene: ENSG00000167711 | OMIM ID: 613168 |
| Drug and gene relationship at DGIdb | |||
SERPINF2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04610 | Complement and coagulation cascades |
Expression of SERPINF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINF2 | 5345 | 205075_at | -0.0005 | 0.9988 | |
| GSE20347 | SERPINF2 | 5345 | 205075_at | 0.1620 | 0.0538 | |
| GSE23400 | SERPINF2 | 5345 | 205075_at | 0.0052 | 0.9096 | |
| GSE26886 | SERPINF2 | 5345 | 205075_at | 1.1882 | 0.0000 | |
| GSE29001 | SERPINF2 | 5345 | 205075_at | 0.1346 | 0.6751 | |
| GSE38129 | SERPINF2 | 5345 | 205075_at | 0.0744 | 0.3399 | |
| GSE45670 | SERPINF2 | 5345 | 205075_at | 0.0528 | 0.6341 | |
| GSE53622 | SERPINF2 | 5345 | 18948 | 0.3096 | 0.0814 | |
| GSE53624 | SERPINF2 | 5345 | 18948 | 0.4426 | 0.0011 | |
| GSE63941 | SERPINF2 | 5345 | 205075_at | 0.2980 | 0.2618 | |
| GSE77861 | SERPINF2 | 5345 | 205075_at | 0.0742 | 0.6125 | |
| GSE97050 | SERPINF2 | 5345 | A_23_P89270 | 0.5502 | 0.0885 | |
| SRP007169 | SERPINF2 | 5345 | RNAseq | 3.5873 | 0.0009 | |
| SRP064894 | SERPINF2 | 5345 | RNAseq | 0.7759 | 0.0590 | |
| SRP133303 | SERPINF2 | 5345 | RNAseq | 0.0246 | 0.9313 | |
| SRP159526 | SERPINF2 | 5345 | RNAseq | 0.4608 | 0.2157 | |
| SRP219564 | SERPINF2 | 5345 | RNAseq | 0.8466 | 0.1719 | |
| TCGA | SERPINF2 | 5345 | RNAseq | 0.4871 | 0.0116 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SERPINF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINF2 | 5345 | 4 | 2 | 24 | |
| GSE20123 | SERPINF2 | 5345 | 4 | 3 | 23 | |
| GSE43470 | SERPINF2 | 5345 | 3 | 6 | 34 | |
| GSE46452 | SERPINF2 | 5345 | 34 | 1 | 24 | |
| GSE47630 | SERPINF2 | 5345 | 8 | 1 | 31 | |
| GSE54993 | SERPINF2 | 5345 | 9 | 3 | 58 | |
| GSE54994 | SERPINF2 | 5345 | 8 | 8 | 37 | |
| GSE60625 | SERPINF2 | 5345 | 4 | 0 | 7 | |
| GSE74703 | SERPINF2 | 5345 | 2 | 3 | 31 | |
| GSE74704 | SERPINF2 | 5345 | 2 | 1 | 17 | |
| TCGA | SERPINF2 | 5345 | 20 | 21 | 55 |
Total number of gains: 98; Total number of losses: 49; Total Number of normals: 341.
Somatic mutations of SERPINF2:
Generating mutation plots.
Highly correlated genes for SERPINF2:
Showing top 20/467 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINF2 | SLC39A3 | 0.82022 | 3 | 0 | 3 |
| SERPINF2 | ZNF827 | 0.793918 | 3 | 0 | 3 |
| SERPINF2 | DGCR2 | 0.770972 | 3 | 0 | 3 |
| SERPINF2 | SSBP4 | 0.757283 | 3 | 0 | 3 |
| SERPINF2 | ROPN1 | 0.755685 | 3 | 0 | 3 |
| SERPINF2 | TRIM47 | 0.753623 | 3 | 0 | 3 |
| SERPINF2 | ADSL | 0.752923 | 3 | 0 | 3 |
| SERPINF2 | ATG2A | 0.747922 | 3 | 0 | 3 |
| SERPINF2 | KDM6B | 0.744792 | 4 | 0 | 4 |
| SERPINF2 | PPP6R3 | 0.740291 | 3 | 0 | 3 |
| SERPINF2 | FAF2 | 0.738446 | 3 | 0 | 3 |
| SERPINF2 | RHBDF2 | 0.738083 | 4 | 0 | 4 |
| SERPINF2 | TPCN2 | 0.736502 | 3 | 0 | 3 |
| SERPINF2 | DERL1 | 0.734319 | 3 | 0 | 3 |
| SERPINF2 | OCIAD2 | 0.732281 | 3 | 0 | 3 |
| SERPINF2 | CCDC86 | 0.731074 | 3 | 0 | 3 |
| SERPINF2 | SDF4 | 0.730021 | 4 | 0 | 3 |
| SERPINF2 | ZNF343 | 0.728592 | 3 | 0 | 3 |
| SERPINF2 | GMCL1 | 0.725121 | 3 | 0 | 3 |
| SERPINF2 | DNAJC11 | 0.723757 | 3 | 0 | 3 |
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