| Full name: ankyrin repeat and BTB domain containing 1 | Alias Symbol: BPOZ|EF1ABP|Btb3|BTBD21 | ||
| Type: protein-coding gene | Cytoband: 3q21.3 | ||
| Entrez ID: 80325 | HGNC ID: HGNC:18275 | Ensembl Gene: ENSG00000114626 | OMIM ID: 608308 |
| Drug and gene relationship at DGIdb | |||
Expression of ABTB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABTB1 | 80325 | 229164_s_at | 0.3914 | 0.3483 | |
| GSE26886 | ABTB1 | 80325 | 229164_s_at | 0.2567 | 0.1154 | |
| GSE45670 | ABTB1 | 80325 | 229164_s_at | 0.0118 | 0.9400 | |
| GSE53622 | ABTB1 | 80325 | 19942 | 0.0793 | 0.3257 | |
| GSE53624 | ABTB1 | 80325 | 19942 | 0.1134 | 0.1274 | |
| GSE63941 | ABTB1 | 80325 | 229164_s_at | 0.3522 | 0.3932 | |
| GSE77861 | ABTB1 | 80325 | 229164_s_at | 0.3219 | 0.0374 | |
| GSE97050 | ABTB1 | 80325 | A_33_P3297444 | -0.1458 | 0.4638 | |
| SRP007169 | ABTB1 | 80325 | RNAseq | 0.9989 | 0.0298 | |
| SRP008496 | ABTB1 | 80325 | RNAseq | 0.5192 | 0.1192 | |
| SRP064894 | ABTB1 | 80325 | RNAseq | 0.6987 | 0.0135 | |
| SRP133303 | ABTB1 | 80325 | RNAseq | -0.0109 | 0.9624 | |
| SRP159526 | ABTB1 | 80325 | RNAseq | 0.3393 | 0.3658 | |
| SRP193095 | ABTB1 | 80325 | RNAseq | 0.6408 | 0.0158 | |
| SRP219564 | ABTB1 | 80325 | RNAseq | -0.0663 | 0.8994 | |
| TCGA | ABTB1 | 80325 | RNAseq | -0.1977 | 0.0026 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABTB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABTB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABTB1 | 80325 | 17 | 0 | 13 | |
| GSE20123 | ABTB1 | 80325 | 17 | 0 | 13 | |
| GSE43470 | ABTB1 | 80325 | 19 | 0 | 24 | |
| GSE46452 | ABTB1 | 80325 | 14 | 5 | 40 | |
| GSE47630 | ABTB1 | 80325 | 17 | 4 | 19 | |
| GSE54993 | ABTB1 | 80325 | 2 | 7 | 61 | |
| GSE54994 | ABTB1 | 80325 | 31 | 3 | 19 | |
| GSE60625 | ABTB1 | 80325 | 0 | 6 | 5 | |
| GSE74703 | ABTB1 | 80325 | 17 | 0 | 19 | |
| GSE74704 | ABTB1 | 80325 | 13 | 0 | 7 | |
| TCGA | ABTB1 | 80325 | 56 | 6 | 34 |
Total number of gains: 203; Total number of losses: 31; Total Number of normals: 254.
Somatic mutations of ABTB1:
Generating mutation plots.
Highly correlated genes for ABTB1:
Showing top 20/268 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABTB1 | YY2 | 0.850497 | 3 | 0 | 3 |
| ABTB1 | INSC | 0.845092 | 3 | 0 | 3 |
| ABTB1 | OR2T27 | 0.835234 | 3 | 0 | 3 |
| ABTB1 | GPR182 | 0.825669 | 3 | 0 | 3 |
| ABTB1 | SLC22A7 | 0.820644 | 3 | 0 | 3 |
| ABTB1 | FFAR1 | 0.818449 | 3 | 0 | 3 |
| ABTB1 | DCDC1 | 0.802379 | 3 | 0 | 3 |
| ABTB1 | RETN | 0.798445 | 3 | 0 | 3 |
| ABTB1 | BBC3 | 0.79823 | 3 | 0 | 3 |
| ABTB1 | PRSS38 | 0.797724 | 3 | 0 | 3 |
| ABTB1 | OR2T1 | 0.785563 | 3 | 0 | 3 |
| ABTB1 | OR2B11 | 0.773897 | 3 | 0 | 3 |
| ABTB1 | TATDN3 | 0.769602 | 3 | 0 | 3 |
| ABTB1 | CIB3 | 0.769122 | 3 | 0 | 3 |
| ABTB1 | ZAN | 0.760196 | 3 | 0 | 3 |
| ABTB1 | F2RL3 | 0.75722 | 3 | 0 | 3 |
| ABTB1 | SLC22A31 | 0.75715 | 3 | 0 | 3 |
| ABTB1 | C9orf153 | 0.756063 | 3 | 0 | 3 |
| ABTB1 | KRTAP2-1 | 0.755573 | 3 | 0 | 3 |
| ABTB1 | TMEM229A | 0.755157 | 3 | 0 | 3 |
For details and further investigation, click here
