| Full name: solute carrier family 22 member 7 | Alias Symbol: NLT|OAT2 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 10864 | HGNC ID: HGNC:10971 | Ensembl Gene: ENSG00000137204 | OMIM ID: 604995 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC22A7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC22A7 | 10864 | 221662_s_at | -0.0812 | 0.7483 | |
| GSE20347 | SLC22A7 | 10864 | 221662_s_at | -0.0336 | 0.7277 | |
| GSE23400 | SLC22A7 | 10864 | 220554_at | -0.2215 | 0.0000 | |
| GSE26886 | SLC22A7 | 10864 | 221662_s_at | 0.0692 | 0.5957 | |
| GSE29001 | SLC22A7 | 10864 | 221662_s_at | -0.0579 | 0.7024 | |
| GSE38129 | SLC22A7 | 10864 | 221662_s_at | -0.1008 | 0.1352 | |
| GSE45670 | SLC22A7 | 10864 | 221662_s_at | -0.0213 | 0.8584 | |
| GSE53622 | SLC22A7 | 10864 | 23349 | -0.0662 | 0.3517 | |
| GSE53624 | SLC22A7 | 10864 | 23349 | -0.1814 | 0.0616 | |
| GSE63941 | SLC22A7 | 10864 | 221662_s_at | 0.0533 | 0.7354 | |
| GSE77861 | SLC22A7 | 10864 | 221661_at | -0.0491 | 0.6136 | |
| GSE97050 | SLC22A7 | 10864 | A_23_P93217 | -0.2327 | 0.3051 | |
| TCGA | SLC22A7 | 10864 | RNAseq | 1.8922 | 0.2676 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC22A7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC22A7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC22A7 | 10864 | 7 | 0 | 23 | |
| GSE20123 | SLC22A7 | 10864 | 7 | 0 | 23 | |
| GSE43470 | SLC22A7 | 10864 | 6 | 0 | 37 | |
| GSE46452 | SLC22A7 | 10864 | 2 | 9 | 48 | |
| GSE47630 | SLC22A7 | 10864 | 8 | 4 | 28 | |
| GSE54993 | SLC22A7 | 10864 | 3 | 2 | 65 | |
| GSE54994 | SLC22A7 | 10864 | 11 | 4 | 38 | |
| GSE60625 | SLC22A7 | 10864 | 0 | 1 | 10 | |
| GSE74703 | SLC22A7 | 10864 | 6 | 0 | 30 | |
| GSE74704 | SLC22A7 | 10864 | 3 | 0 | 17 | |
| TCGA | SLC22A7 | 10864 | 20 | 13 | 63 |
Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.
Somatic mutations of SLC22A7:
Generating mutation plots.
Highly correlated genes for SLC22A7:
Showing top 20/955 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC22A7 | YY2 | 0.889425 | 3 | 0 | 3 |
| SLC22A7 | GDF7 | 0.879252 | 3 | 0 | 3 |
| SLC22A7 | SHISA8 | 0.847447 | 3 | 0 | 3 |
| SLC22A7 | RNF180 | 0.841863 | 3 | 0 | 3 |
| SLC22A7 | FAM131A | 0.841778 | 3 | 0 | 3 |
| SLC22A7 | SPRED3 | 0.838693 | 3 | 0 | 3 |
| SLC22A7 | ANKRD33B | 0.837966 | 3 | 0 | 3 |
| SLC22A7 | RBM43 | 0.837632 | 3 | 0 | 3 |
| SLC22A7 | TOR2A | 0.827354 | 3 | 0 | 3 |
| SLC22A7 | DCDC1 | 0.821814 | 3 | 0 | 3 |
| SLC22A7 | ABTB1 | 0.820644 | 3 | 0 | 3 |
| SLC22A7 | OR10AD1 | 0.807914 | 3 | 0 | 3 |
| SLC22A7 | INSC | 0.807713 | 3 | 0 | 3 |
| SLC22A7 | PRSS38 | 0.804991 | 3 | 0 | 3 |
| SLC22A7 | KCP | 0.801797 | 3 | 0 | 3 |
| SLC22A7 | C1QL2 | 0.800581 | 3 | 0 | 3 |
| SLC22A7 | STAC3 | 0.79685 | 3 | 0 | 3 |
| SLC22A7 | MAGEA8 | 0.796539 | 3 | 0 | 3 |
| SLC22A7 | MRGPRG | 0.795744 | 3 | 0 | 3 |
| SLC22A7 | STRC | 0.791723 | 3 | 0 | 3 |
For details and further investigation, click here
