ZAN

 

Full name: zonadhesin (gene/pseudogene) Alias Symbol: 
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 7455 HGNC ID: HGNC:12857 Ensembl Gene: ENSG00000146839 OMIM ID: 602372
Drug and gene relationship at DGIdb

 

Expression of ZAN:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZAN 7455 224264_x_at 0.0769 0.7382
GSE26886 ZAN 7455 224264_x_at 0.4456 0.0123
GSE45670 ZAN 7455 224264_x_at 0.1360 0.2201
GSE53622 ZAN 7455 65601 0.2163 0.0042
GSE53624 ZAN 7455 65601 0.1131 0.2285
GSE63941 ZAN 7455 224264_x_at -0.0840 0.6059
GSE77861 ZAN 7455 224264_x_at -0.0906 0.4730
GSE97050 ZAN 7455 A_23_P82286 -0.0216 0.9369
TCGA ZAN 7455 RNAseq 1.7619 0.0190

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by ZAN expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZAN:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZAN 7455 13 0 17
GSE20123 ZAN 7455 13 0 17
GSE43470 ZAN 7455 7 2 34
GSE46452 ZAN 7455 11 1 47
GSE47630 ZAN 7455 7 3 30
GSE54993 ZAN 7455 1 9 60
GSE54994 ZAN 7455 16 3 34
GSE60625 ZAN 7455 0 0 11
GSE74703 ZAN 7455 7 1 28
GSE74704 ZAN 7455 9 0 11
TCGA ZAN 7455 53 6 37

Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.  


 

Somatic mutations of ZAN:

 

Generating mutation plots.

 

Highly correlated genes for ZAN:

 

Showing top 20/348 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZANYY20.85499303
ZANST8SIA10.828306303
ZANGPR1820.818829404
ZANPRSS380.809807303
ZANNKX6-30.808862303
ZANSRCIN10.80785303
ZANMRGPRG0.807488303
ZANTNFRSF250.803139303
ZANC1QL20.79584303
ZANCPLX20.794305303
ZANOR2B110.784341303
ZANOR2T10.780414303
ZANSERPINA100.774572303
ZANDCDC10.77131303
ZANPAX60.770484404
ZANBSX0.768073303
ZANSORCS30.763046303
ZANABTB10.760196303
ZANSLC18A30.759336303
ZANOR2A50.758216303

For details and further investigation, click here