| Full name: keratin associated protein 2-1 | Alias Symbol: KAP2.1A | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 81872 | HGNC ID: HGNC:16775 | Ensembl Gene: ENSG00000212725 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRTAP2-1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTAP2-1 | 81872 | 234691_at | 0.1142 | 0.6386 | |
| GSE26886 | KRTAP2-1 | 81872 | 234691_at | -0.0872 | 0.3082 | |
| GSE45670 | KRTAP2-1 | 81872 | 234691_at | 0.0766 | 0.3626 | |
| GSE53622 | KRTAP2-1 | 81872 | 67165 | 0.2818 | 0.0002 | |
| GSE53624 | KRTAP2-1 | 81872 | 67165 | -0.0899 | 0.3525 | |
| GSE63941 | KRTAP2-1 | 81872 | 234691_at | -0.0733 | 0.5891 | |
| GSE77861 | KRTAP2-1 | 81872 | 234691_at | -0.1221 | 0.2315 | |
| GSE97050 | KRTAP2-1 | 81872 | A_24_P76854 | -0.2092 | 0.2812 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP2-1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP2-1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP2-1 | 81872 | 7 | 1 | 22 | |
| GSE20123 | KRTAP2-1 | 81872 | 7 | 1 | 22 | |
| GSE43470 | KRTAP2-1 | 81872 | 1 | 2 | 40 | |
| GSE46452 | KRTAP2-1 | 81872 | 34 | 0 | 25 | |
| GSE47630 | KRTAP2-1 | 81872 | 8 | 1 | 31 | |
| GSE54993 | KRTAP2-1 | 81872 | 3 | 4 | 63 | |
| GSE54994 | KRTAP2-1 | 81872 | 8 | 5 | 40 | |
| GSE60625 | KRTAP2-1 | 81872 | 4 | 0 | 7 | |
| GSE74703 | KRTAP2-1 | 81872 | 1 | 1 | 34 | |
| GSE74704 | KRTAP2-1 | 81872 | 4 | 1 | 15 |
Total number of gains: 77; Total number of losses: 16; Total Number of normals: 299.
Somatic mutations of KRTAP2-1:
Generating mutation plots.
Highly correlated genes for KRTAP2-1:
Showing top 20/336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP2-1 | FOXE3 | 0.830213 | 3 | 0 | 3 |
| KRTAP2-1 | DCDC1 | 0.808563 | 3 | 0 | 3 |
| KRTAP2-1 | YY2 | 0.794 | 3 | 0 | 3 |
| KRTAP2-1 | CPLX2 | 0.793588 | 3 | 0 | 3 |
| KRTAP2-1 | STRC | 0.793399 | 3 | 0 | 3 |
| KRTAP2-1 | NKX6-3 | 0.791723 | 3 | 0 | 3 |
| KRTAP2-1 | LINC00632 | 0.781264 | 3 | 0 | 3 |
| KRTAP2-1 | OR2T1 | 0.776479 | 3 | 0 | 3 |
| KRTAP2-1 | OR2A5 | 0.77481 | 3 | 0 | 3 |
| KRTAP2-1 | OR10AD1 | 0.773494 | 3 | 0 | 3 |
| KRTAP2-1 | TOR2A | 0.772136 | 3 | 0 | 3 |
| KRTAP2-1 | SPRED3 | 0.770053 | 3 | 0 | 3 |
| KRTAP2-1 | PLA2G2C | 0.769834 | 3 | 0 | 3 |
| KRTAP2-1 | OR2T27 | 0.758112 | 3 | 0 | 3 |
| KRTAP2-1 | CLTCL1 | 0.75767 | 4 | 0 | 4 |
| KRTAP2-1 | SPACA3 | 0.757206 | 3 | 0 | 3 |
| KRTAP2-1 | BBC3 | 0.756417 | 3 | 0 | 3 |
| KRTAP2-1 | SHISA8 | 0.756318 | 3 | 0 | 3 |
| KRTAP2-1 | ABTB1 | 0.755573 | 3 | 0 | 3 |
| KRTAP2-1 | PRSS38 | 0.755112 | 3 | 0 | 3 |
For details and further investigation, click here
