| Full name: alkylglycerone phosphate synthase | Alias Symbol: ADHAPS|ADAS|ALDHPSY|ADPS|ADAP-S | ||
| Type: protein-coding gene | Cytoband: 2q31.2 | ||
| Entrez ID: 8540 | HGNC ID: HGNC:327 | Ensembl Gene: ENSG00000018510 | OMIM ID: 603051 |
| Drug and gene relationship at DGIdb | |||
Expression of AGPS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGPS | 8540 | 225114_at | 0.6396 | 0.3648 | |
| GSE20347 | AGPS | 8540 | 205401_at | 0.7255 | 0.0126 | |
| GSE23400 | AGPS | 8540 | 205401_at | 0.9916 | 0.0000 | |
| GSE26886 | AGPS | 8540 | 225108_at | 0.5295 | 0.0301 | |
| GSE29001 | AGPS | 8540 | 205401_at | 0.7880 | 0.0230 | |
| GSE38129 | AGPS | 8540 | 205401_at | 0.8976 | 0.0000 | |
| GSE45670 | AGPS | 8540 | 225114_at | 0.6933 | 0.0005 | |
| GSE53622 | AGPS | 8540 | 66661 | 0.5410 | 0.0000 | |
| GSE53624 | AGPS | 8540 | 66661 | 0.9629 | 0.0000 | |
| GSE63941 | AGPS | 8540 | 225114_at | 0.0549 | 0.9302 | |
| GSE77861 | AGPS | 8540 | 205401_at | 0.3679 | 0.2526 | |
| GSE97050 | AGPS | 8540 | A_23_P368645 | 0.2735 | 0.4516 | |
| SRP007169 | AGPS | 8540 | RNAseq | 1.0017 | 0.0061 | |
| SRP008496 | AGPS | 8540 | RNAseq | 1.0822 | 0.0000 | |
| SRP064894 | AGPS | 8540 | RNAseq | 0.6425 | 0.0004 | |
| SRP133303 | AGPS | 8540 | RNAseq | 0.6834 | 0.0000 | |
| SRP159526 | AGPS | 8540 | RNAseq | 0.1034 | 0.7925 | |
| SRP193095 | AGPS | 8540 | RNAseq | 0.1876 | 0.3097 | |
| SRP219564 | AGPS | 8540 | RNAseq | 0.2285 | 0.5039 | |
| TCGA | AGPS | 8540 | RNAseq | 0.1282 | 0.0220 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by AGPS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGPS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGPS | 8540 | 11 | 0 | 19 | |
| GSE20123 | AGPS | 8540 | 11 | 0 | 19 | |
| GSE43470 | AGPS | 8540 | 5 | 1 | 37 | |
| GSE46452 | AGPS | 8540 | 1 | 4 | 54 | |
| GSE47630 | AGPS | 8540 | 4 | 4 | 32 | |
| GSE54993 | AGPS | 8540 | 0 | 5 | 65 | |
| GSE54994 | AGPS | 8540 | 11 | 4 | 38 | |
| GSE60625 | AGPS | 8540 | 0 | 3 | 8 | |
| GSE74703 | AGPS | 8540 | 4 | 1 | 31 | |
| GSE74704 | AGPS | 8540 | 6 | 0 | 14 | |
| TCGA | AGPS | 8540 | 29 | 7 | 60 |
Total number of gains: 82; Total number of losses: 29; Total Number of normals: 377.
Somatic mutations of AGPS:
Generating mutation plots.
Highly correlated genes for AGPS:
Showing top 20/1232 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGPS | SENP1 | 0.768684 | 3 | 0 | 3 |
| AGPS | CCDC14 | 0.732748 | 3 | 0 | 3 |
| AGPS | ZNF766 | 0.731182 | 3 | 0 | 3 |
| AGPS | MTHFD1L | 0.722928 | 3 | 0 | 3 |
| AGPS | ZNF700 | 0.720178 | 3 | 0 | 3 |
| AGPS | ZBTB34 | 0.716949 | 3 | 0 | 3 |
| AGPS | ZNF808 | 0.714752 | 3 | 0 | 3 |
| AGPS | MZT1 | 0.710931 | 4 | 0 | 4 |
| AGPS | ERLEC1 | 0.707907 | 3 | 0 | 3 |
| AGPS | ASAP2 | 0.697282 | 3 | 0 | 3 |
| AGPS | LACTB | 0.692104 | 4 | 0 | 4 |
| AGPS | BOD1 | 0.6899 | 4 | 0 | 4 |
| AGPS | RNF6 | 0.687722 | 3 | 0 | 3 |
| AGPS | RABEP1 | 0.682735 | 5 | 0 | 5 |
| AGPS | SLC38A9 | 0.681991 | 3 | 0 | 3 |
| AGPS | EME1 | 0.680172 | 4 | 0 | 3 |
| AGPS | ADNP | 0.67977 | 3 | 0 | 3 |
| AGPS | DIS3 | 0.679751 | 4 | 0 | 3 |
| AGPS | ANLN | 0.679726 | 7 | 0 | 6 |
| AGPS | TMEM17 | 0.674209 | 4 | 0 | 3 |
For details and further investigation, click here
