| Full name: lactamase beta | Alias Symbol: FLJ14902 | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 114294 | HGNC ID: HGNC:16468 | Ensembl Gene: ENSG00000103642 | OMIM ID: 608440 |
| Drug and gene relationship at DGIdb | |||
Expression of LACTB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LACTB | 114294 | 226354_at | 0.2909 | 0.4825 | |
| GSE26886 | LACTB | 114294 | 226354_at | -0.5519 | 0.0231 | |
| GSE45670 | LACTB | 114294 | 226354_at | -0.0790 | 0.6343 | |
| GSE53622 | LACTB | 114294 | 56963 | 0.4351 | 0.0000 | |
| GSE53624 | LACTB | 114294 | 56963 | 0.1295 | 0.2776 | |
| GSE63941 | LACTB | 114294 | 226354_at | -2.4020 | 0.0014 | |
| GSE77861 | LACTB | 114294 | 226354_at | -0.0363 | 0.8390 | |
| GSE97050 | LACTB | 114294 | A_24_P53051 | 0.3163 | 0.3233 | |
| SRP007169 | LACTB | 114294 | RNAseq | -0.0826 | 0.8465 | |
| SRP008496 | LACTB | 114294 | RNAseq | -0.3617 | 0.1715 | |
| SRP064894 | LACTB | 114294 | RNAseq | 0.5275 | 0.0082 | |
| SRP133303 | LACTB | 114294 | RNAseq | 0.4598 | 0.0094 | |
| SRP159526 | LACTB | 114294 | RNAseq | -0.2176 | 0.6073 | |
| SRP193095 | LACTB | 114294 | RNAseq | -0.0686 | 0.6007 | |
| SRP219564 | LACTB | 114294 | RNAseq | 0.3241 | 0.3832 | |
| TCGA | LACTB | 114294 | RNAseq | 0.0487 | 0.4776 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LACTB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LACTB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LACTB | 114294 | 8 | 2 | 20 | |
| GSE20123 | LACTB | 114294 | 8 | 2 | 20 | |
| GSE43470 | LACTB | 114294 | 4 | 6 | 33 | |
| GSE46452 | LACTB | 114294 | 3 | 7 | 49 | |
| GSE47630 | LACTB | 114294 | 8 | 10 | 22 | |
| GSE54993 | LACTB | 114294 | 5 | 6 | 59 | |
| GSE54994 | LACTB | 114294 | 6 | 8 | 39 | |
| GSE60625 | LACTB | 114294 | 4 | 0 | 7 | |
| GSE74703 | LACTB | 114294 | 4 | 3 | 29 | |
| GSE74704 | LACTB | 114294 | 4 | 2 | 14 | |
| TCGA | LACTB | 114294 | 10 | 17 | 69 |
Total number of gains: 64; Total number of losses: 63; Total Number of normals: 361.
Somatic mutations of LACTB:
Generating mutation plots.
Highly correlated genes for LACTB:
Showing top 20/538 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LACTB | ADCY7 | 0.820124 | 3 | 0 | 3 |
| LACTB | PDLIM2 | 0.815678 | 3 | 0 | 3 |
| LACTB | RNF149 | 0.796738 | 3 | 0 | 3 |
| LACTB | MVP | 0.793665 | 3 | 0 | 3 |
| LACTB | DOK1 | 0.78469 | 3 | 0 | 3 |
| LACTB | TGDS | 0.781023 | 3 | 0 | 3 |
| LACTB | NXT2 | 0.775403 | 3 | 0 | 3 |
| LACTB | REST | 0.775097 | 3 | 0 | 3 |
| LACTB | NUDT5 | 0.774561 | 3 | 0 | 3 |
| LACTB | SFPQ | 0.769985 | 3 | 0 | 3 |
| LACTB | SGMS2 | 0.766453 | 3 | 0 | 3 |
| LACTB | NAT1 | 0.759991 | 3 | 0 | 3 |
| LACTB | SGSH | 0.75182 | 3 | 0 | 3 |
| LACTB | FAF2 | 0.751211 | 4 | 0 | 4 |
| LACTB | LRRC17 | 0.749236 | 3 | 0 | 3 |
| LACTB | EIF4G3 | 0.746662 | 3 | 0 | 3 |
| LACTB | SLC24A1 | 0.745236 | 3 | 0 | 3 |
| LACTB | RNF6 | 0.739289 | 3 | 0 | 3 |
| LACTB | SPIN4 | 0.738356 | 3 | 0 | 3 |
| LACTB | MGAT4B | 0.738206 | 4 | 0 | 4 |
For details and further investigation, click here
