| Full name: anillin actin binding protein | Alias Symbol: ANILLIN|Scraps|scra | ||
| Type: protein-coding gene | Cytoband: 7p14.2 | ||
| Entrez ID: 54443 | HGNC ID: HGNC:14082 | Ensembl Gene: ENSG00000011426 | OMIM ID: 616027 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ANLN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANLN | 54443 | 222608_s_at | 1.3850 | 0.0584 | |
| GSE26886 | ANLN | 54443 | 222608_s_at | 0.5338 | 0.1617 | |
| GSE45670 | ANLN | 54443 | 222608_s_at | 1.4380 | 0.0000 | |
| GSE53622 | ANLN | 54443 | 49019 | 1.6462 | 0.0000 | |
| GSE53624 | ANLN | 54443 | 49019 | 1.9814 | 0.0000 | |
| GSE63941 | ANLN | 54443 | 222608_s_at | 2.2713 | 0.0138 | |
| GSE77861 | ANLN | 54443 | 222608_s_at | 1.2458 | 0.1046 | |
| GSE97050 | ANLN | 54443 | A_23_P356684 | 0.9711 | 0.1189 | |
| SRP007169 | ANLN | 54443 | RNAseq | 1.8380 | 0.0001 | |
| SRP008496 | ANLN | 54443 | RNAseq | 1.7404 | 0.0000 | |
| SRP064894 | ANLN | 54443 | RNAseq | 1.6104 | 0.0001 | |
| SRP133303 | ANLN | 54443 | RNAseq | 1.7393 | 0.0000 | |
| SRP159526 | ANLN | 54443 | RNAseq | 0.9411 | 0.0003 | |
| SRP193095 | ANLN | 54443 | RNAseq | 1.1620 | 0.0000 | |
| TCGA | ANLN | 54443 | RNAseq | 0.9579 | 0.0000 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by ANLN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANLN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANLN | 54443 | 16 | 0 | 14 | |
| GSE20123 | ANLN | 54443 | 16 | 0 | 14 | |
| GSE43470 | ANLN | 54443 | 4 | 0 | 39 | |
| GSE46452 | ANLN | 54443 | 11 | 1 | 47 | |
| GSE47630 | ANLN | 54443 | 8 | 1 | 31 | |
| GSE54993 | ANLN | 54443 | 0 | 7 | 63 | |
| GSE54994 | ANLN | 54443 | 18 | 3 | 32 | |
| GSE60625 | ANLN | 54443 | 0 | 0 | 11 | |
| GSE74703 | ANLN | 54443 | 4 | 0 | 32 | |
| GSE74704 | ANLN | 54443 | 9 | 0 | 11 | |
| TCGA | ANLN | 54443 | 53 | 6 | 37 |
Total number of gains: 139; Total number of losses: 18; Total Number of normals: 331.
Somatic mutations of ANLN:
Generating mutation plots.
Highly correlated genes for ANLN:
Showing top 20/1889 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANLN | TTK | 0.854719 | 8 | 0 | 8 |
| ANLN | KIF23 | 0.852306 | 9 | 0 | 9 |
| ANLN | RACGAP1 | 0.844752 | 7 | 0 | 7 |
| ANLN | DEPDC1B | 0.830762 | 7 | 0 | 7 |
| ANLN | BORA | 0.825764 | 6 | 0 | 6 |
| ANLN | MMS22L | 0.825083 | 3 | 0 | 3 |
| ANLN | CLSPN | 0.824236 | 6 | 0 | 6 |
| ANLN | SLC9A1 | 0.822254 | 3 | 0 | 3 |
| ANLN | BUB1 | 0.818313 | 9 | 0 | 9 |
| ANLN | HJURP | 0.818158 | 8 | 0 | 8 |
| ANLN | DLGAP5 | 0.816724 | 8 | 0 | 8 |
| ANLN | KIF14 | 0.812037 | 9 | 0 | 9 |
| ANLN | CEP55 | 0.811199 | 9 | 0 | 9 |
| ANLN | NDC80 | 0.807914 | 9 | 0 | 8 |
| ANLN | CENPE | 0.807887 | 9 | 0 | 9 |
| ANLN | CDCA2 | 0.804329 | 7 | 0 | 7 |
| ANLN | PRC1 | 0.804191 | 9 | 0 | 9 |
| ANLN | CENPF | 0.801842 | 8 | 0 | 8 |
| ANLN | CDKN3 | 0.800792 | 9 | 0 | 9 |
| ANLN | FAM89A | 0.795868 | 3 | 0 | 3 |
For details and further investigation, click here
