| Full name: rabaptin, RAB GTPase binding effector protein 1 | Alias Symbol: neurocrescin|RAB5EP|RABPT5|rabaptin-5 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 9135 | HGNC ID: HGNC:17677 | Ensembl Gene: ENSG00000029725 | OMIM ID: 603616 |
| Drug and gene relationship at DGIdb | |||
Expression of RABEP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RABEP1 | 9135 | 225064_at | 0.0730 | 0.8983 | |
| GSE20347 | RABEP1 | 9135 | 214552_s_at | 0.0606 | 0.3866 | |
| GSE23400 | RABEP1 | 9135 | 214552_s_at | 0.0604 | 0.1112 | |
| GSE26886 | RABEP1 | 9135 | 225064_at | 0.8152 | 0.0155 | |
| GSE29001 | RABEP1 | 9135 | 214552_s_at | 0.2270 | 0.4168 | |
| GSE38129 | RABEP1 | 9135 | 214552_s_at | 0.0404 | 0.6081 | |
| GSE45670 | RABEP1 | 9135 | 225064_at | 0.2582 | 0.2739 | |
| GSE53622 | RABEP1 | 9135 | 40533 | 0.3479 | 0.0000 | |
| GSE53624 | RABEP1 | 9135 | 19084 | 0.0772 | 0.2755 | |
| GSE63941 | RABEP1 | 9135 | 225064_at | 0.1411 | 0.8147 | |
| GSE77861 | RABEP1 | 9135 | 231002_s_at | 0.0062 | 0.9638 | |
| GSE97050 | RABEP1 | 9135 | A_33_P3275998 | 0.1770 | 0.3803 | |
| SRP007169 | RABEP1 | 9135 | RNAseq | 1.9149 | 0.0000 | |
| SRP008496 | RABEP1 | 9135 | RNAseq | 2.1923 | 0.0000 | |
| SRP064894 | RABEP1 | 9135 | RNAseq | 0.3946 | 0.0694 | |
| SRP133303 | RABEP1 | 9135 | RNAseq | 0.1301 | 0.2693 | |
| SRP159526 | RABEP1 | 9135 | RNAseq | 0.7699 | 0.0176 | |
| SRP193095 | RABEP1 | 9135 | RNAseq | 0.2602 | 0.0006 | |
| SRP219564 | RABEP1 | 9135 | RNAseq | 0.7599 | 0.0825 | |
| TCGA | RABEP1 | 9135 | RNAseq | -0.0975 | 0.0437 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RABEP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RABEP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RABEP1 | 9135 | 5 | 2 | 23 | |
| GSE20123 | RABEP1 | 9135 | 5 | 3 | 22 | |
| GSE43470 | RABEP1 | 9135 | 1 | 6 | 36 | |
| GSE46452 | RABEP1 | 9135 | 34 | 1 | 24 | |
| GSE47630 | RABEP1 | 9135 | 7 | 1 | 32 | |
| GSE54993 | RABEP1 | 9135 | 4 | 3 | 63 | |
| GSE54994 | RABEP1 | 9135 | 5 | 8 | 40 | |
| GSE60625 | RABEP1 | 9135 | 4 | 0 | 7 | |
| GSE74703 | RABEP1 | 9135 | 1 | 3 | 32 | |
| GSE74704 | RABEP1 | 9135 | 3 | 1 | 16 | |
| TCGA | RABEP1 | 9135 | 18 | 20 | 58 |
Total number of gains: 87; Total number of losses: 48; Total Number of normals: 353.
Somatic mutations of RABEP1:
Generating mutation plots.
Highly correlated genes for RABEP1:
Showing top 20/473 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RABEP1 | TMEM65 | 0.805996 | 3 | 0 | 3 |
| RABEP1 | HSF2 | 0.783221 | 3 | 0 | 3 |
| RABEP1 | ZNF627 | 0.742831 | 3 | 0 | 3 |
| RABEP1 | NIPA2 | 0.741325 | 3 | 0 | 3 |
| RABEP1 | DDHD1 | 0.713771 | 4 | 0 | 4 |
| RABEP1 | DLGAP4 | 0.712744 | 3 | 0 | 3 |
| RABEP1 | TEX261 | 0.711762 | 3 | 0 | 3 |
| RABEP1 | SNRPG | 0.711562 | 3 | 0 | 3 |
| RABEP1 | AMZ2 | 0.704434 | 3 | 0 | 3 |
| RABEP1 | CNTLN | 0.703489 | 3 | 0 | 3 |
| RABEP1 | ORC3 | 0.701488 | 3 | 0 | 3 |
| RABEP1 | FAM49A | 0.699526 | 4 | 0 | 4 |
| RABEP1 | CHAMP1 | 0.69487 | 3 | 0 | 3 |
| RABEP1 | TCP11L1 | 0.691019 | 3 | 0 | 3 |
| RABEP1 | DAP3 | 0.68982 | 3 | 0 | 3 |
| RABEP1 | ABHD15 | 0.689473 | 3 | 0 | 3 |
| RABEP1 | CBX1 | 0.685704 | 5 | 0 | 4 |
| RABEP1 | CD44 | 0.685493 | 3 | 0 | 3 |
| RABEP1 | VPS37A | 0.684668 | 3 | 0 | 3 |
| RABEP1 | AGPS | 0.682735 | 5 | 0 | 5 |
For details and further investigation, click here
