| Full name: endoplasmic reticulum lectin 1 | Alias Symbol: CL25084|XTP3TPB|XTP3-B|ERLECTIN | ||
| Type: protein-coding gene | Cytoband: 2p16.2 | ||
| Entrez ID: 27248 | HGNC ID: HGNC:25222 | Ensembl Gene: ENSG00000068912 | OMIM ID: 611229 |
| Drug and gene relationship at DGIdb | |||
Expression of ERLEC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERLEC1 | 27248 | 224628_at | -0.0197 | 0.9646 | |
| GSE26886 | ERLEC1 | 27248 | 224628_at | 0.1333 | 0.5719 | |
| GSE45670 | ERLEC1 | 27248 | 224628_at | -0.2159 | 0.1799 | |
| GSE53622 | ERLEC1 | 27248 | 49748 | 0.1226 | 0.0923 | |
| GSE53624 | ERLEC1 | 27248 | 49748 | 0.0863 | 0.2237 | |
| GSE63941 | ERLEC1 | 27248 | 224628_at | -1.8419 | 0.0006 | |
| GSE77861 | ERLEC1 | 27248 | 224630_at | 0.1711 | 0.1178 | |
| GSE97050 | ERLEC1 | 27248 | A_33_P3325018 | 0.2530 | 0.3131 | |
| SRP007169 | ERLEC1 | 27248 | RNAseq | -0.0053 | 0.9900 | |
| SRP008496 | ERLEC1 | 27248 | RNAseq | 0.1276 | 0.6201 | |
| SRP064894 | ERLEC1 | 27248 | RNAseq | 0.1424 | 0.4019 | |
| SRP133303 | ERLEC1 | 27248 | RNAseq | 0.5005 | 0.0007 | |
| SRP159526 | ERLEC1 | 27248 | RNAseq | 0.6238 | 0.0017 | |
| SRP193095 | ERLEC1 | 27248 | RNAseq | 0.0115 | 0.9469 | |
| SRP219564 | ERLEC1 | 27248 | RNAseq | 0.3844 | 0.2041 | |
| TCGA | ERLEC1 | 27248 | RNAseq | -0.1294 | 0.0052 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ERLEC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERLEC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERLEC1 | 27248 | 8 | 0 | 22 | |
| GSE20123 | ERLEC1 | 27248 | 7 | 0 | 23 | |
| GSE43470 | ERLEC1 | 27248 | 5 | 0 | 38 | |
| GSE46452 | ERLEC1 | 27248 | 2 | 4 | 53 | |
| GSE47630 | ERLEC1 | 27248 | 8 | 0 | 32 | |
| GSE54993 | ERLEC1 | 27248 | 0 | 5 | 65 | |
| GSE54994 | ERLEC1 | 27248 | 12 | 2 | 39 | |
| GSE60625 | ERLEC1 | 27248 | 0 | 3 | 8 | |
| GSE74703 | ERLEC1 | 27248 | 5 | 0 | 31 | |
| GSE74704 | ERLEC1 | 27248 | 8 | 0 | 12 | |
| TCGA | ERLEC1 | 27248 | 36 | 2 | 58 |
Total number of gains: 91; Total number of losses: 16; Total Number of normals: 381.
Somatic mutations of ERLEC1:
Generating mutation plots.
Highly correlated genes for ERLEC1:
Showing top 20/598 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERLEC1 | C9orf78 | 0.808602 | 3 | 0 | 3 |
| ERLEC1 | ZMYM6 | 0.807079 | 3 | 0 | 3 |
| ERLEC1 | HNRNPA0 | 0.763303 | 3 | 0 | 3 |
| ERLEC1 | FZD6 | 0.756466 | 3 | 0 | 3 |
| ERLEC1 | SNX19 | 0.738652 | 4 | 0 | 4 |
| ERLEC1 | TSNAX | 0.737431 | 5 | 0 | 4 |
| ERLEC1 | MAP4K4 | 0.736409 | 3 | 0 | 3 |
| ERLEC1 | STRAP | 0.735563 | 4 | 0 | 4 |
| ERLEC1 | CCDC3 | 0.734261 | 3 | 0 | 3 |
| ERLEC1 | C11orf96 | 0.733757 | 3 | 0 | 3 |
| ERLEC1 | IMPAD1 | 0.733624 | 3 | 0 | 3 |
| ERLEC1 | STAMBPL1 | 0.729827 | 3 | 0 | 3 |
| ERLEC1 | CREB3L2 | 0.728681 | 4 | 0 | 3 |
| ERLEC1 | ENG | 0.727222 | 4 | 0 | 4 |
| ERLEC1 | SENP1 | 0.724863 | 3 | 0 | 3 |
| ERLEC1 | UBFD1 | 0.723841 | 3 | 0 | 3 |
| ERLEC1 | C11orf24 | 0.721409 | 3 | 0 | 3 |
| ERLEC1 | HERC2 | 0.718586 | 3 | 0 | 3 |
| ERLEC1 | SH3RF3 | 0.716716 | 4 | 0 | 4 |
| ERLEC1 | GLS | 0.715222 | 3 | 0 | 3 |
For details and further investigation, click here
