| Full name: activity dependent neuroprotector homeobox | Alias Symbol: KIAA0784|ADNP1 | ||
| Type: protein-coding gene | Cytoband: 20q13.13 | ||
| Entrez ID: 23394 | HGNC ID: HGNC:15766 | Ensembl Gene: ENSG00000101126 | OMIM ID: 611386 |
| Drug and gene relationship at DGIdb | |||
Expression of ADNP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADNP | 23394 | 201773_at | 0.4776 | 0.2787 | |
| GSE20347 | ADNP | 23394 | 201773_at | 0.2852 | 0.0616 | |
| GSE23400 | ADNP | 23394 | 201773_at | 0.5890 | 0.0000 | |
| GSE26886 | ADNP | 23394 | 201773_at | -0.1548 | 0.5504 | |
| GSE29001 | ADNP | 23394 | 201773_at | 0.4566 | 0.1893 | |
| GSE38129 | ADNP | 23394 | 201773_at | 0.3601 | 0.0055 | |
| GSE45670 | ADNP | 23394 | 201773_at | 0.2399 | 0.0916 | |
| GSE53622 | ADNP | 23394 | 11750 | 0.4767 | 0.0000 | |
| GSE53624 | ADNP | 23394 | 122051 | 0.2957 | 0.0001 | |
| GSE63941 | ADNP | 23394 | 201773_at | 0.4787 | 0.1218 | |
| GSE77861 | ADNP | 23394 | 201773_at | 0.2137 | 0.4201 | |
| GSE97050 | ADNP | 23394 | A_23_P254179 | 0.2207 | 0.4880 | |
| SRP007169 | ADNP | 23394 | RNAseq | 1.1335 | 0.0005 | |
| SRP008496 | ADNP | 23394 | RNAseq | 1.2647 | 0.0000 | |
| SRP064894 | ADNP | 23394 | RNAseq | 0.1408 | 0.3592 | |
| SRP133303 | ADNP | 23394 | RNAseq | 0.3710 | 0.0012 | |
| SRP159526 | ADNP | 23394 | RNAseq | 0.0959 | 0.5840 | |
| SRP193095 | ADNP | 23394 | RNAseq | 0.1773 | 0.0190 | |
| SRP219564 | ADNP | 23394 | RNAseq | 0.2860 | 0.2385 | |
| TCGA | ADNP | 23394 | RNAseq | 0.0330 | 0.4316 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ADNP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADNP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADNP | 23394 | 16 | 2 | 12 | |
| GSE20123 | ADNP | 23394 | 16 | 2 | 12 | |
| GSE43470 | ADNP | 23394 | 13 | 0 | 30 | |
| GSE46452 | ADNP | 23394 | 29 | 0 | 30 | |
| GSE47630 | ADNP | 23394 | 24 | 1 | 15 | |
| GSE54993 | ADNP | 23394 | 0 | 17 | 53 | |
| GSE54994 | ADNP | 23394 | 27 | 0 | 26 | |
| GSE60625 | ADNP | 23394 | 0 | 0 | 11 | |
| GSE74703 | ADNP | 23394 | 11 | 0 | 25 | |
| GSE74704 | ADNP | 23394 | 12 | 0 | 8 | |
| TCGA | ADNP | 23394 | 46 | 3 | 47 |
Total number of gains: 194; Total number of losses: 25; Total Number of normals: 269.
Somatic mutations of ADNP:
Generating mutation plots.
Highly correlated genes for ADNP:
Showing top 20/1038 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADNP | HMBOX1 | 0.784036 | 3 | 0 | 3 |
| ADNP | ZNF496 | 0.75651 | 3 | 0 | 3 |
| ADNP | B3GALT6 | 0.752463 | 3 | 0 | 3 |
| ADNP | NFKB1 | 0.743879 | 3 | 0 | 3 |
| ADNP | PUS10 | 0.742319 | 3 | 0 | 3 |
| ADNP | CDC42SE2 | 0.739414 | 3 | 0 | 3 |
| ADNP | PDE7A | 0.738177 | 3 | 0 | 3 |
| ADNP | USE1 | 0.735484 | 3 | 0 | 3 |
| ADNP | UTP23 | 0.723755 | 4 | 0 | 4 |
| ADNP | NUDT3 | 0.717007 | 3 | 0 | 3 |
| ADNP | ZNF567 | 0.708803 | 3 | 0 | 3 |
| ADNP | PET117 | 0.707146 | 3 | 0 | 3 |
| ADNP | DHX33 | 0.703152 | 3 | 0 | 3 |
| ADNP | KLHL20 | 0.699179 | 3 | 0 | 3 |
| ADNP | AZIN1 | 0.698132 | 7 | 0 | 6 |
| ADNP | GPI | 0.697062 | 3 | 0 | 3 |
| ADNP | SLC39A10 | 0.694043 | 4 | 0 | 4 |
| ADNP | SLC7A6OS | 0.69334 | 3 | 0 | 3 |
| ADNP | LRRC58 | 0.686132 | 4 | 0 | 4 |
| ADNP | ZNF397 | 0.685255 | 4 | 0 | 4 |
For details and further investigation, click here
