| Full name: coiled-coil domain containing 14 | Alias Symbol: FLJ12892|DKFZp434L1050 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 64770 | HGNC ID: HGNC:25766 | Ensembl Gene: ENSG00000175455 | OMIM ID: 617147 |
| Drug and gene relationship at DGIdb | |||
Expression of CCDC14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC14 | 64770 | 225017_at | 0.6854 | 0.1120 | |
| GSE26886 | CCDC14 | 64770 | 225017_at | 0.8367 | 0.0423 | |
| GSE45670 | CCDC14 | 64770 | 225017_at | 0.4551 | 0.0326 | |
| GSE53622 | CCDC14 | 64770 | 38668 | 0.8357 | 0.0000 | |
| GSE53624 | CCDC14 | 64770 | 38668 | 0.8343 | 0.0000 | |
| GSE63941 | CCDC14 | 64770 | 225017_at | -0.7980 | 0.1544 | |
| GSE77861 | CCDC14 | 64770 | 225017_at | 0.5503 | 0.2371 | |
| GSE97050 | CCDC14 | 64770 | A_23_P384056 | 0.1716 | 0.3989 | |
| SRP007169 | CCDC14 | 64770 | RNAseq | 1.6646 | 0.0001 | |
| SRP008496 | CCDC14 | 64770 | RNAseq | 1.8359 | 0.0000 | |
| SRP064894 | CCDC14 | 64770 | RNAseq | 0.9223 | 0.0000 | |
| SRP133303 | CCDC14 | 64770 | RNAseq | 0.8653 | 0.0000 | |
| SRP159526 | CCDC14 | 64770 | RNAseq | 1.0620 | 0.0460 | |
| SRP193095 | CCDC14 | 64770 | RNAseq | 0.8433 | 0.0000 | |
| SRP219564 | CCDC14 | 64770 | RNAseq | 0.7339 | 0.0142 | |
| TCGA | CCDC14 | 64770 | RNAseq | 0.1353 | 0.0407 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CCDC14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC14 | 64770 | 17 | 0 | 13 | |
| GSE20123 | CCDC14 | 64770 | 17 | 0 | 13 | |
| GSE43470 | CCDC14 | 64770 | 20 | 0 | 23 | |
| GSE46452 | CCDC14 | 64770 | 14 | 5 | 40 | |
| GSE47630 | CCDC14 | 64770 | 17 | 4 | 19 | |
| GSE54993 | CCDC14 | 64770 | 2 | 7 | 61 | |
| GSE54994 | CCDC14 | 64770 | 30 | 4 | 19 | |
| GSE60625 | CCDC14 | 64770 | 0 | 6 | 5 | |
| GSE74703 | CCDC14 | 64770 | 16 | 0 | 20 | |
| GSE74704 | CCDC14 | 64770 | 13 | 0 | 7 | |
| TCGA | CCDC14 | 64770 | 54 | 6 | 36 |
Total number of gains: 200; Total number of losses: 32; Total Number of normals: 256.
Somatic mutations of CCDC14:
Generating mutation plots.
Highly correlated genes for CCDC14:
Showing top 20/772 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC14 | ZNF451 | 0.821273 | 4 | 0 | 4 |
| CCDC14 | UPF1 | 0.784105 | 3 | 0 | 3 |
| CCDC14 | CD3EAP | 0.777254 | 3 | 0 | 3 |
| CCDC14 | FUBP1 | 0.776536 | 3 | 0 | 3 |
| CCDC14 | TP53I11 | 0.76902 | 3 | 0 | 3 |
| CCDC14 | TGFBRAP1 | 0.768256 | 3 | 0 | 3 |
| CCDC14 | ZNF32 | 0.766179 | 3 | 0 | 3 |
| CCDC14 | PRMT1 | 0.763379 | 3 | 0 | 3 |
| CCDC14 | GLO1 | 0.761862 | 3 | 0 | 3 |
| CCDC14 | C9orf64 | 0.75589 | 3 | 0 | 3 |
| CCDC14 | ZNF266 | 0.753146 | 3 | 0 | 3 |
| CCDC14 | CORO1C | 0.745952 | 3 | 0 | 3 |
| CCDC14 | PILRA | 0.745861 | 3 | 0 | 3 |
| CCDC14 | PDE6D | 0.745546 | 3 | 0 | 3 |
| CCDC14 | MAP1S | 0.743139 | 3 | 0 | 3 |
| CCDC14 | WDR70 | 0.739929 | 3 | 0 | 3 |
| CCDC14 | MBD4 | 0.738196 | 6 | 0 | 6 |
| CCDC14 | AGPS | 0.732748 | 3 | 0 | 3 |
| CCDC14 | HELZ | 0.730363 | 3 | 0 | 3 |
| CCDC14 | TOPBP1 | 0.729207 | 8 | 0 | 8 |
For details and further investigation, click here
