| Full name: AT-hook containing transcription factor 1 | Alias Symbol: ELYS | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 25909 | HGNC ID: HGNC:24618 | Ensembl Gene: ENSG00000153207 | OMIM ID: 610853 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of AHCTF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHCTF1 | 25909 | 214766_s_at | 1.1757 | 0.0193 | |
| GSE20347 | AHCTF1 | 25909 | 214766_s_at | 0.8443 | 0.0000 | |
| GSE23400 | AHCTF1 | 25909 | 214766_s_at | 0.4005 | 0.0000 | |
| GSE26886 | AHCTF1 | 25909 | 226115_at | 1.4219 | 0.0000 | |
| GSE29001 | AHCTF1 | 25909 | 214766_s_at | 0.7325 | 0.0438 | |
| GSE38129 | AHCTF1 | 25909 | 214766_s_at | 0.7505 | 0.0000 | |
| GSE45670 | AHCTF1 | 25909 | 214766_s_at | 0.3659 | 0.0234 | |
| GSE53622 | AHCTF1 | 25909 | 91112 | 0.4918 | 0.0000 | |
| GSE53624 | AHCTF1 | 25909 | 103259 | 0.8581 | 0.0000 | |
| GSE63941 | AHCTF1 | 25909 | 214766_s_at | 0.3157 | 0.3224 | |
| GSE77861 | AHCTF1 | 25909 | 214766_s_at | 0.8070 | 0.0032 | |
| GSE97050 | AHCTF1 | 25909 | A_33_P3666346 | 0.2997 | 0.3116 | |
| SRP007169 | AHCTF1 | 25909 | RNAseq | 1.5284 | 0.0004 | |
| SRP008496 | AHCTF1 | 25909 | RNAseq | 1.5171 | 0.0000 | |
| SRP064894 | AHCTF1 | 25909 | RNAseq | 0.3054 | 0.2336 | |
| SRP133303 | AHCTF1 | 25909 | RNAseq | 0.6262 | 0.0001 | |
| SRP159526 | AHCTF1 | 25909 | RNAseq | 0.6787 | 0.0133 | |
| SRP193095 | AHCTF1 | 25909 | RNAseq | 0.6022 | 0.0000 | |
| SRP219564 | AHCTF1 | 25909 | RNAseq | 0.7146 | 0.1055 | |
| TCGA | AHCTF1 | 25909 | RNAseq | 0.0572 | 0.2220 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by AHCTF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHCTF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHCTF1 | 25909 | 7 | 1 | 22 | |
| GSE20123 | AHCTF1 | 25909 | 7 | 1 | 22 | |
| GSE43470 | AHCTF1 | 25909 | 4 | 3 | 36 | |
| GSE46452 | AHCTF1 | 25909 | 4 | 2 | 53 | |
| GSE47630 | AHCTF1 | 25909 | 15 | 1 | 24 | |
| GSE54993 | AHCTF1 | 25909 | 0 | 6 | 64 | |
| GSE54994 | AHCTF1 | 25909 | 18 | 0 | 35 | |
| GSE60625 | AHCTF1 | 25909 | 0 | 0 | 11 | |
| GSE74703 | AHCTF1 | 25909 | 4 | 1 | 31 | |
| GSE74704 | AHCTF1 | 25909 | 2 | 0 | 18 | |
| TCGA | AHCTF1 | 25909 | 47 | 5 | 44 |
Total number of gains: 108; Total number of losses: 20; Total Number of normals: 360.
Somatic mutations of AHCTF1:
Generating mutation plots.
Highly correlated genes for AHCTF1:
Showing top 20/2021 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHCTF1 | PPP1R16A | 0.805253 | 3 | 0 | 3 |
| AHCTF1 | MTERF3 | 0.770997 | 8 | 0 | 8 |
| AHCTF1 | SGTB | 0.769438 | 3 | 0 | 3 |
| AHCTF1 | UCKL1 | 0.766278 | 3 | 0 | 3 |
| AHCTF1 | C20orf194 | 0.765977 | 3 | 0 | 3 |
| AHCTF1 | U2SURP | 0.765962 | 9 | 0 | 9 |
| AHCTF1 | C1orf131 | 0.763809 | 8 | 0 | 8 |
| AHCTF1 | COLEC11 | 0.76353 | 3 | 0 | 3 |
| AHCTF1 | GATAD2B | 0.760066 | 3 | 0 | 3 |
| AHCTF1 | ZBTB37 | 0.758709 | 3 | 0 | 3 |
| AHCTF1 | GEMIN5 | 0.745745 | 4 | 0 | 4 |
| AHCTF1 | FLVCR1 | 0.744348 | 8 | 0 | 8 |
| AHCTF1 | GMCL1 | 0.744032 | 3 | 0 | 3 |
| AHCTF1 | RICTOR | 0.741012 | 3 | 0 | 3 |
| AHCTF1 | ZNF397 | 0.740865 | 3 | 0 | 3 |
| AHCTF1 | SEC22C | 0.740451 | 3 | 0 | 3 |
| AHCTF1 | ANP32E | 0.739873 | 11 | 0 | 11 |
| AHCTF1 | NACC1 | 0.738772 | 4 | 0 | 4 |
| AHCTF1 | HEATR1 | 0.73867 | 13 | 0 | 12 |
| AHCTF1 | SAMD1 | 0.736418 | 4 | 0 | 4 |
For details and further investigation, click here
