| Full name: SEC22 homolog C, vesicle trafficking protein | Alias Symbol: MGC13261|MGC5373 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 9117 | HGNC ID: HGNC:16828 | Ensembl Gene: ENSG00000093183 | OMIM ID: 604028 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC22C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC22C | 9117 | 225460_at | -0.0940 | 0.8865 | |
| GSE26886 | SEC22C | 9117 | 225460_at | 1.1179 | 0.0000 | |
| GSE45670 | SEC22C | 9117 | 225460_at | -0.5907 | 0.0038 | |
| GSE53622 | SEC22C | 9117 | 41344 | 0.0499 | 0.5475 | |
| GSE53624 | SEC22C | 9117 | 41344 | 0.1600 | 0.1548 | |
| GSE63941 | SEC22C | 9117 | 225460_at | -1.2609 | 0.0009 | |
| GSE77861 | SEC22C | 9117 | 225460_at | 0.1929 | 0.3999 | |
| GSE97050 | SEC22C | 9117 | A_33_P3258702 | 0.2460 | 0.3932 | |
| SRP007169 | SEC22C | 9117 | RNAseq | 1.2267 | 0.0744 | |
| SRP008496 | SEC22C | 9117 | RNAseq | 1.6825 | 0.0006 | |
| SRP064894 | SEC22C | 9117 | RNAseq | 0.1364 | 0.4741 | |
| SRP133303 | SEC22C | 9117 | RNAseq | -0.0418 | 0.7516 | |
| SRP159526 | SEC22C | 9117 | RNAseq | -0.1987 | 0.4824 | |
| SRP193095 | SEC22C | 9117 | RNAseq | -0.0418 | 0.8227 | |
| SRP219564 | SEC22C | 9117 | RNAseq | 0.1317 | 0.7596 | |
| TCGA | SEC22C | 9117 | RNAseq | -0.2798 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by SEC22C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC22C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC22C | 9117 | 0 | 19 | 11 | |
| GSE20123 | SEC22C | 9117 | 0 | 19 | 11 | |
| GSE43470 | SEC22C | 9117 | 0 | 21 | 22 | |
| GSE46452 | SEC22C | 9117 | 2 | 17 | 40 | |
| GSE47630 | SEC22C | 9117 | 1 | 24 | 15 | |
| GSE54993 | SEC22C | 9117 | 7 | 2 | 61 | |
| GSE54994 | SEC22C | 9117 | 1 | 34 | 18 | |
| GSE60625 | SEC22C | 9117 | 5 | 0 | 6 | |
| GSE74703 | SEC22C | 9117 | 0 | 17 | 19 | |
| GSE74704 | SEC22C | 9117 | 0 | 13 | 7 | |
| TCGA | SEC22C | 9117 | 1 | 71 | 24 |
Total number of gains: 17; Total number of losses: 237; Total Number of normals: 234.
Somatic mutations of SEC22C:
Generating mutation plots.
Highly correlated genes for SEC22C:
Showing top 20/1222 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC22C | NOL9 | 0.827173 | 3 | 0 | 3 |
| SEC22C | STOML1 | 0.821568 | 3 | 0 | 3 |
| SEC22C | SGTB | 0.799168 | 6 | 0 | 6 |
| SEC22C | USP42 | 0.795055 | 3 | 0 | 3 |
| SEC22C | TSNAX | 0.79084 | 3 | 0 | 3 |
| SEC22C | DGKH | 0.790767 | 3 | 0 | 3 |
| SEC22C | CHAMP1 | 0.78775 | 3 | 0 | 3 |
| SEC22C | TMEM173 | 0.777919 | 3 | 0 | 3 |
| SEC22C | NCOR2 | 0.773992 | 3 | 0 | 3 |
| SEC22C | SLC38A10 | 0.767185 | 3 | 0 | 3 |
| SEC22C | C9orf78 | 0.764611 | 4 | 0 | 4 |
| SEC22C | THEM4 | 0.764387 | 3 | 0 | 3 |
| SEC22C | ZCCHC3 | 0.762943 | 3 | 0 | 3 |
| SEC22C | GRB10 | 0.761916 | 4 | 0 | 4 |
| SEC22C | TCTN3 | 0.761179 | 5 | 0 | 5 |
| SEC22C | TP53I13 | 0.760165 | 3 | 0 | 3 |
| SEC22C | ITIH5 | 0.759729 | 3 | 0 | 3 |
| SEC22C | HSD11B1 | 0.755767 | 4 | 0 | 4 |
| SEC22C | CCNB1IP1 | 0.755478 | 4 | 0 | 4 |
| SEC22C | CXCL12 | 0.752704 | 3 | 0 | 3 |
For details and further investigation, click here
