| Full name: protein phosphatase 1 regulatory subunit 16A | Alias Symbol: MGC14333|MYPT3 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 84988 | HGNC ID: HGNC:14941 | Ensembl Gene: ENSG00000160972 | OMIM ID: 609172 |
| Drug and gene relationship at DGIdb | |||
Expression of PPP1R16A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPP1R16A | 84988 | 225203_at | 1.0433 | 0.1227 | |
| GSE26886 | PPP1R16A | 84988 | 225203_at | 0.9131 | 0.0006 | |
| GSE45670 | PPP1R16A | 84988 | 225203_at | -0.2569 | 0.2089 | |
| GSE53622 | PPP1R16A | 84988 | 47270 | 0.1634 | 0.1200 | |
| GSE53624 | PPP1R16A | 84988 | 47270 | 0.0427 | 0.6153 | |
| GSE63941 | PPP1R16A | 84988 | 225203_at | 1.2584 | 0.0846 | |
| GSE77861 | PPP1R16A | 84988 | 225203_at | 0.1100 | 0.7978 | |
| GSE97050 | PPP1R16A | 84988 | A_23_P157715 | 0.1994 | 0.5817 | |
| SRP007169 | PPP1R16A | 84988 | RNAseq | -0.2475 | 0.6167 | |
| SRP064894 | PPP1R16A | 84988 | RNAseq | 0.7808 | 0.0070 | |
| SRP133303 | PPP1R16A | 84988 | RNAseq | 0.3022 | 0.1609 | |
| SRP159526 | PPP1R16A | 84988 | RNAseq | 0.5162 | 0.0357 | |
| SRP193095 | PPP1R16A | 84988 | RNAseq | 0.1750 | 0.4195 | |
| SRP219564 | PPP1R16A | 84988 | RNAseq | 0.8944 | 0.1407 | |
| TCGA | PPP1R16A | 84988 | RNAseq | -0.0274 | 0.6511 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PPP1R16A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPP1R16A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPP1R16A | 84988 | 17 | 1 | 12 | |
| GSE20123 | PPP1R16A | 84988 | 17 | 1 | 12 | |
| GSE43470 | PPP1R16A | 84988 | 16 | 2 | 25 | |
| GSE46452 | PPP1R16A | 84988 | 28 | 0 | 31 | |
| GSE47630 | PPP1R16A | 84988 | 25 | 1 | 14 | |
| GSE54993 | PPP1R16A | 84988 | 0 | 25 | 45 | |
| GSE54994 | PPP1R16A | 84988 | 39 | 1 | 13 | |
| GSE60625 | PPP1R16A | 84988 | 3 | 4 | 4 | |
| GSE74703 | PPP1R16A | 84988 | 14 | 1 | 21 | |
| GSE74704 | PPP1R16A | 84988 | 10 | 0 | 10 | |
| TCGA | PPP1R16A | 84988 | 63 | 2 | 31 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of PPP1R16A:
Generating mutation plots.
Highly correlated genes for PPP1R16A:
Showing top 20/651 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPP1R16A | C12orf45 | 0.863331 | 3 | 0 | 3 |
| PPP1R16A | UBQLN4 | 0.845736 | 3 | 0 | 3 |
| PPP1R16A | RPL35A | 0.839531 | 3 | 0 | 3 |
| PPP1R16A | SLC41A1 | 0.839463 | 3 | 0 | 3 |
| PPP1R16A | CLK2 | 0.834971 | 3 | 0 | 3 |
| PPP1R16A | CCS | 0.823566 | 3 | 0 | 3 |
| PPP1R16A | FANCL | 0.814428 | 3 | 0 | 3 |
| PPP1R16A | ALKBH6 | 0.813649 | 3 | 0 | 3 |
| PPP1R16A | DHX36 | 0.812446 | 3 | 0 | 3 |
| PPP1R16A | TMEM185B | 0.81202 | 3 | 0 | 3 |
| PPP1R16A | PFDN2 | 0.810845 | 3 | 0 | 3 |
| PPP1R16A | AHCTF1 | 0.805253 | 3 | 0 | 3 |
| PPP1R16A | AGO2 | 0.803562 | 3 | 0 | 3 |
| PPP1R16A | SSB | 0.801585 | 3 | 0 | 3 |
| PPP1R16A | FLVCR1 | 0.800942 | 3 | 0 | 3 |
| PPP1R16A | GMPS | 0.796973 | 3 | 0 | 3 |
| PPP1R16A | RNF4 | 0.791857 | 3 | 0 | 3 |
| PPP1R16A | NAF1 | 0.788903 | 3 | 0 | 3 |
| PPP1R16A | DDX55 | 0.786621 | 3 | 0 | 3 |
| PPP1R16A | CCDC59 | 0.785587 | 3 | 0 | 3 |
For details and further investigation, click here
